Glomerular Disorders Quiz
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Questions and Answers

What is the primary cause of acute glomerulonephritis?

  • Antibodies directed against the glomerular basement membrane
  • Deposition of circulating immune complexes (correct)
  • Inflammatory damage due to infection
  • Complement activation

    • What characterizes the urine sediment in nephrotic sediment?

  • Presence of antibodies
  • Complement activation
  • Large amounts of protein (correct)
  • Red and white blood cells and protein

    • What causes lupus nephritis?

  • Complement activation
  • Inflammatory damage due to infection
  • Deposition of circulating immune complexes
  • Formation of autoantibodies against double-stranded DNA (dsDNA) and nucleosomes in the glomerulus (correct)

    • What is the primary cause of IgA nephropathy?

    <p>Binding of abnormal IgA to mesangial cells in the glomerulus</p> Signup and view all the answers

    What characterizes focal segmental glomerulosclerosis?

    <p>It involves some but not all glomeruli and glomerular capillaries</p> Signup and view all the answers

    What is the primary cause of membranous nephropathy?

    <p>Complement-mediated glomerular injury with increased glomerular permeability and glomerulosclerosis</p> Signup and view all the answers

    What is a primary cause of glomerular disorders?

    <p>Immune injury, infection, ischemia, toxins or drugs, or vascular disorders</p> Signup and view all the answers

    What is the primary cause of nephrotic syndrome?

    <p>Increased capillary permeability and loss of membrane negative charge</p> Signup and view all the answers

    What is the characteristic sign of nephritic syndrome?

    <p>Hematuria and red blood cell casts in the urine</p> Signup and view all the answers

    Which type of glomerulonephritis involves complement deposition and crescent formation?

    <p>Membranoproliferative glomerulonephritis</p> Signup and view all the answers

    What is the cause of lupus nephritis?

    <p>Autoantibodies against dsDNA and nucleosomes in the glomerulus</p> Signup and view all the answers

    What is the characteristic feature of chronic glomerulonephritis?

    <p>Deterioration of the glomerulus and progressive loss of renal function</p> Signup and view all the answers

    What is the characteristic of mesangial proliferative glomerulonephritis?

    <p>Involves deposits of immune complex in the mesangium with mesangial cell proliferation</p> Signup and view all the answers

    What is the development of diabetic nephropathy associated with?

    <p>Chronic hyperglycemia</p> Signup and view all the answers

    What is the result of RPGN (Rapidly Progressive Glomerulonephritis)?

    <p>Proliferation of glomerular capillary endothelial cells and a rapid loss of renal function</p> Signup and view all the answers

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