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Glomerular Disorders Quiz

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Questions and Answers

What is the primary cause of acute glomerulonephritis?

Antibodies directed against the glomerular basement membrane
Deposition of circulating immune complexes (correct)
Inflammatory damage due to infection
Complement activation

What characterizes the urine sediment in nephrotic sediment?

Presence of antibodies
Complement activation
Large amounts of protein (correct)
Red and white blood cells and protein

What causes lupus nephritis?

Complement activation
Inflammatory damage due to infection
Deposition of circulating immune complexes
Formation of autoantibodies against double-stranded DNA (dsDNA) and nucleosomes in the glomerulus (correct)

What is the primary cause of IgA nephropathy?

Binding of abnormal IgA to mesangial cells in the glomerulus (D) Signup and view all the answers

What characterizes focal segmental glomerulosclerosis?

It involves some but not all glomeruli and glomerular capillaries (D) Signup and view all the answers

What is the primary cause of membranous nephropathy?

Complement-mediated glomerular injury with increased glomerular permeability and glomerulosclerosis (A) Signup and view all the answers

What is a primary cause of glomerular disorders?

Immune injury, infection, ischemia, toxins or drugs, or vascular disorders (C) Signup and view all the answers

What is the primary cause of nephrotic syndrome?

Increased capillary permeability and loss of membrane negative charge (A) Signup and view all the answers

What is the characteristic sign of nephritic syndrome?

Hematuria and red blood cell casts in the urine (B) Signup and view all the answers

Which type of glomerulonephritis involves complement deposition and crescent formation?

Membranoproliferative glomerulonephritis (A) Signup and view all the answers

What is the cause of lupus nephritis?

Autoantibodies against dsDNA and nucleosomes in the glomerulus (A) Signup and view all the answers

What is the characteristic feature of chronic glomerulonephritis?

Deterioration of the glomerulus and progressive loss of renal function (B) Signup and view all the answers

What is the characteristic of mesangial proliferative glomerulonephritis?

Involves deposits of immune complex in the mesangium with mesangial cell proliferation (D) Signup and view all the answers

What is the development of diabetic nephropathy associated with?

Chronic hyperglycemia (D) Signup and view all the answers

What is the result of RPGN (Rapidly Progressive Glomerulonephritis)?

Proliferation of glomerular capillary endothelial cells and a rapid loss of renal function (D) Signup and view all the answers

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