Globulin & Glucose in Cerebrospinal Fluid

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Questions and Answers

What is Pandy test used for?

Detecting globulin in CSF.

Globulin concentration in CSF is decreased in multiple sclerosis and neurosyphilis.

False (B)

How is glucose estimated in CSF?

By glucose oxidase method or Folin-Wu method.

What is the normal concentration of glucose in CSF?

<p>50-80 mg%</p> Signup and view all the answers

The level of glucose is increased in pyogenic meningitis and tuberculous meningitis.

<p>False (B)</p> Signup and view all the answers

Flashcards

Globulin Test (Pandy Test)

Two drops of CSF are added to 2ml of phenol reagent (Pandy reagent). Globulins are precipitated if present in high concentration in CSF.

Increased Globulin Indicates

Globulin concentration is increased in multiple sclerosis and neurosyphilis.

CSF Glucose Methods

Glucose estimation in CSF is done by glucose oxidase method or Folin-Wu method.

Normal CSF Glucose Level

Normal glucose concentration in CSF is 50-80 mg%.

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Decreased Glucose Indicates

Glucose levels are decreased in pyogenic meningitis and tuberculous meningitis.

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Study Notes

  • The image is about Globulin (Pandy test) and Glucose

Globulin (Pandy Test)

  • Two drops of Cerebrospinal fluid (CSF) are added to 2ml of phenol reagent (Pandy reagent)
  • Globulins are precipitated if present in high concentration in CSF
  • Globulin is increased in multiple sclerosis and neurosyphilis

Glucose

  • The estimation of glucose is done by glucose oxidase method or Folin-Wu
  • Normally, the concentration of glucose in CSF is 50 - 80 mg%
  • The level of glucose is decreased in pyogenic meningitis and tuberculous meningitis

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