Questions and Answers
What is the drug class for glipizide?
What is a key drug for glipizide?
Glucotrol
What is the mechanism of action for glipizide?
Lowers blood glucose levels by stimulating the release of insulin from the pancreas and increasing sensitivity of insulin at receptor sites, decreases hepatic glucose production.
Common adverse reactions for glipizide include ______.
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How is glipizide metabolized?
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What are some drug interactions for glipizide?
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What nursing care should be taken for glipizide?
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Glipizide is prescribed for ______.
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Study Notes
Glipizide Overview
- Classified as an antidiabetic medication within the sulfonylureas category.
- Common brand name is Glucotrol.
Mechanism of Action
- Reduces blood glucose by stimulating insulin release from the pancreas.
- Enhances sensitivity to insulin at receptor sites.
- Decreases glucose production in the liver.
Adverse Reactions
- Common side effects include dizziness, drowsiness, headache, weakness, and gastrointestinal issues (constipation, cramps, diarrhea).
- Serious adverse effects may include drug-induced hepatitis, hypoglycemia, and various blood disorders (aplastic anemia, agranulocytosis, hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia).
- Possible reactions include increased appetite, nausea, vomiting, photosensitivity, and rash.
Pharmacokinetics
- Primarily metabolized by the liver.
Drug Interactions
- Potential interactions with oral contraceptives, thyroid preparations, androgens, MAO inhibitors, and beta-adrenergics.
Nursing Care Considerations
- Monitor for hypoglycemia.
- Assess for allergies to sulfonamides.
- Regularly check complete blood count (CBC).
Indications for Use
- Prescribed mainly for the management of Type II diabetes.
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Description
This quiz provides an overview of Glipizide, an antidiabetic medication classified under sulfonylureas. It explores its mechanism of action, common and serious adverse reactions, pharmacokinetics, and potential drug interactions. Test your knowledge on this important medication used for managing diabetes.
