Glaucoma Management Quiz
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Questions and Answers

What is glaucoma characterized by?

  • Schlemm Canal resistance and ciliary muscle bypassing
  • ONH Atrophy and secondary induced programmed retinal ganglion cell death (correct)
  • Decreased Ocular Blood Flow and increased IOP
  • Increased Episcleral VP and decreased Diastolic BP
  • What are the primary mechanisms of damage (PMOD) in glaucoma?

  • Resistance to Trabecular Aqueous Outflow and resistance to Uveoscleral Aqueous Outflow
  • Elevated intraocular pressure and decreased ocular blood flow (correct)
  • Vasculospastic DX and hyperviscosity syndrome
  • Increased herniation of TM cytoskeleton and decreased inflammatory signaling to EC Schlemm Canal
  • What are the two outflow methods causing elevated intraocular pressure?

  • Vasculospastic DX and hyperviscosity syndrome
  • Decreased diastolic BP and increased episcleral VP
  • Increased herniation of TM cytoskeleton and decreased inflammatory signaling to EC Schlemm Canal
  • Resistance to Trabecular Aqueous Outflow and Resistance to Uveoscleral Aqueous Outflow (correct)
  • What is the mechanism of Uveoscleral Aqueous Outflow (USO)?

    <p>Goes back to ciliary body through CB Band, through ciliary muscle bypassing muscle fibers which are restricted by collagen</p> Signup and view all the answers

    What is the formula for Ocular Blood Flow (OBF)?

    <p>OBF = Perfusion Pressure of Artery - Perfusion Pressure of Vein</p> Signup and view all the answers

    What factors lead to decreased Ocular Blood Flow (DOBF)?

    <p>Decreased Diastolic BP/Elevated IOP and Vasculospastic DX/Hyperviscosity Syndrome/EIOP</p> Signup and view all the answers

    What concept is related to Ocular Biomechanical Properties (OBMP)?

    <p>Vascular Concept of OBF</p> Signup and view all the answers

    What is the role of Prostaglandin agonists in decreasing IOP?

    <p>Break down collagen between fibers, thus decreasing IOP</p> Signup and view all the answers

    What is the mechanism of Uveoscleral Aqueous Outflow (USO)?

    <p>Goes back to ciliary body through CB Band, through ciliary muscle bypassing muscle fibers which are restricted by collagen</p> Signup and view all the answers

    Which factor is viewed as a protective factor for corneal rigidity?

    <p>Central Corneal Thickness (CCT)</p> Signup and view all the answers

    What does an increase in Corneal Hysteresis (CH) value indicate?

    <p>Better biomechanics and more ability to hold pressure</p> Signup and view all the answers

    What does a higher Corneal Resistance Factor (CRF) imply?

    <p>More rigidity and higher IOP</p> Signup and view all the answers

    Which factor does the Ocular Response Analyzer (ORA) measure?

    <p>IOP by applanation of the cornea</p> Signup and view all the answers

    What does decreased Corneal Hysteresis (CH) lead to?

    <p>Increased IOP</p> Signup and view all the answers

    What is the relation of cupping in the optic disc size to glaucoma risk?

    <p>0.4/0.4-1.5mm: more risk</p> Signup and view all the answers

    Which factor is not a strong risk factor for glaucoma?

    <p>Diabetes</p> Signup and view all the answers

    What does long axial length in myopia lead to?

    <p>Decreased blood flow</p> Signup and view all the answers

    What is the primary race associated with primary open-angle glaucoma?

    <p>Black</p> Signup and view all the answers

    What is the goal of Pharmacological Medical Therapy for glaucoma?

    <p>Reduction in the mean IOP</p> Signup and view all the answers

    What does elevated IOP relate to in terms of glaucoma risk?

    <p>Increased risk of optic neuropathy</p> Signup and view all the answers

    What is the mechanism believed to lead to cell death in glaucoma due to glutamate excitotoxicity?

    <p>Increased Mg+ influx</p> Signup and view all the answers

    Which factor is related to the ability of the cornea to absorb energy?

    <p>Corneal Hysteresis (CH)</p> Signup and view all the answers

    What is the role of Nitric Oxide Synthesis in glaucoma?

    <p>Causing cell death</p> Signup and view all the answers

    What does an increase in Corneal Hysteresis (CH) value indicate?

    <p>Better biomechanics and more ability to hold pressure</p> Signup and view all the answers

    What does long axial length in myopia lead to?

    <p>Decreased blood flow</p> Signup and view all the answers

    What is the mechanism believed to lead to cell death in glaucoma due to glutamate excitotoxicity?

    <p>Increased Ca+ Influx</p> Signup and view all the answers

    What does elevated IOP relate to in terms of glaucoma risk?

    <p>Optic neuropathy</p> Signup and view all the answers

    What factors lead to decreased Ocular Blood Flow (DOBF)?

    <p>Myopia and diabetes</p> Signup and view all the answers

    What is the formula for Ocular Blood Flow (OBF)?

    <p>OBF = CRF - CCT</p> Signup and view all the answers

    What is the mechanism of Uveoscleral Aqueous Outflow (USO)?

    <p>Decreasing IOP through alternative outflow pathway</p> Signup and view all the answers

    What does a higher Corneal Resistance Factor (CRF) imply?

    <p>Increased IOP</p> Signup and view all the answers

    What is the primary role of Prostaglandin agonists in decreasing IOP?

    <p>Enhancing uveoscleral outflow</p> Signup and view all the answers

    What are the primary mechanisms of damage (PMOD) in glaucoma?

    <p>Elevated intraocular pressure (EIOP) and Decreased Ocular Blood Flow (DOBF)</p> Signup and view all the answers

    What causes EIOP in glaucoma?

    <p>Resistance to Trabecular Aqueous Outflow (TO) and Resistance to Uveoscleral Aqueous Outflow (USO)</p> Signup and view all the answers

    What is the relationship between Ocular Blood Flow (OBF) and Diastolic BP (DBP) in glaucoma?

    <p>Decreased DBP leads to Uncompensated DOPP and decreased Ocular Blood Flow (DOBF)</p> Signup and view all the answers

    What is the mechanism of Uveoscleral Aqueous Outflow (USO) and its relation to IOP?

    <p>USO Mechanism: Goes back to ciliary body through CB Band, through ciliary muscle bypassing muscle fibers which are restricted by collagen</p> Signup and view all the answers

    What is the role of Prostaglandin agonists in decreasing IOP in glaucoma?

    <p>Prostaglandin agonists break down collagen between fibers, thus decreasing IOP</p> Signup and view all the answers

    What concept is related to Ocular Biomechanical Properties (OBMP) in glaucoma?

    <p>Corneal Hysteresis (CH) and Corneal Resistance Factor (CRF)</p> Signup and view all the answers

    What does a higher Corneal Hysteresis (CH) value indicate in glaucoma?

    <p>Greater corneal viscoelastic properties and better prognosis</p> Signup and view all the answers

    What does an increase in Corneal Resistance Factor (CRF) imply in glaucoma?

    <p>Stiffer cornea and increased risk of progression</p> Signup and view all the answers

    What does long axial length in myopia lead to in terms of glaucoma risk?

    <p>Increased risk of glaucoma development</p> Signup and view all the answers

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