23 Questions
What is the role of germ cells?
To give rise to gametes
What molecules are localized in the cytoplasm and give rise to the germ cells in fish, frogs, and flies?
Germplasm
What environmental factor can affect the likelihood of sex determination in reptiles?
Temperature
Which gene affects the maleness of an organism and is found on the Y chromosome?
Sry
What triggers an autoregulatory mechanism to continue the process for male development?
SOX9 induced by SRY
Which factor is needed to ensure the repression of SOX9 for ovarian development?
Foxl2
What process do germ cells undergo to move to the gonads and be stored until the organism reaches adult stage?
Primordial germ cell migration (PGC migration)
Which process is regulated by the suppression of testis development?
Ovarian development
Which factor is needed to ensure the repression of SOX9 for ovarian development?
Foxl2
What environmental factor can affect the likelihood of sex determination in reptiles?
Temperature
What is the role of germ cells?
Move to the gonads and be stored until adult stage
Which gene affects the maleness of an organism and is found on the Y chromosome?
SRY gene
What triggers an autoregulatory mechanism to continue the process for male development?
SRY gene presence inducing SOX9
What process do germ cells undergo to move to the gonads and be stored until the organism reaches adult stage?
Primordial germ cell migration
Which process is regulated by the suppression of testis development?
Ovarian development
What molecules are localized in the cytoplasm and give rise to germ cells in fish, frogs, and flies?
Germplasm
What is the role of the Sry gene in sex determination?
It triggers an autoregulatory mechanism for male development
In which animal is sex determination affected by temperature?
Reptiles
What is the function of the g-protein CXCR4 in primordial germ cell migration?
It targets the gonad and expresses ligand SDF1
Which gene is associated with stem cell pluripotency?
Oct4
What process do germ cells undergo to be stored in the gonads until the organism reaches adult stage?
Primordial germ cell migration
What is the effect of the absence of Foxl2 on ovarian development?
Expression of SOX9 and presence of oocytes
Which molecule(s) localized in the cytoplasm give rise to germ cells in fish, frogs, and flies?
Germplasm
This quiz covers the characteristics and production of germ cells, which give rise to gametes and are totipotent. It also includes information on the molecular processes involved in germ cell production in different organisms.
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