Recent

  • Show all results for ""

🎧 New: AI-Generated Podcasts Turn your study notes into engaging audio conversations. Learn more

GERD and PUD Pathophysiology Quiz
54 Questions
0 Views

GERD and PUD Pathophysiology Quiz

Created by
@SmootherTiger

Podcast Beta

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a risk factor for Peptic Ulcer Disease (PUD)?

  • Hypertension
  • Diabetes mellitus
  • Asthma
  • Stress-related mucosal damage (correct)

    • What is a common cause of Peptic Ulcer Disease (PUD) extending deep into the gastrointestinal mucosa?

  • NSAID use (correct)
  • Hormonal imbalance
  • Bacterial infection
  • Excessive fiber intake

    • Which of the following is NOT a risk factor for Peptic Ulcer Disease (PUD)?

  • NSAID use
  • Fruit and vegetable intake (correct)
  • H. pylori infection
  • Alcohol consumption

    • What is the main bacterial cause associated with Peptic Ulcer Disease (PUD)?

    <p>H. pylori</p> Signup and view all the answers

    How can Stress-Related Mucosal Damage (SRMD) occur?

    <p>By taking NSAIDs</p> Signup and view all the answers

    Which diagnostic method is commonly used for Gastroesophageal Reflux Disease (GERD)?

    <p>Endoscopy</p> Signup and view all the answers

    What is the main mechanism through which NSAIDs contribute to peptic ulcer disease (PUD)?

    <p>Inhibition of prostaglandin synthesis</p> Signup and view all the answers

    Which of the following risk factors is NOT associated with peptic ulcer disease (PUD)?

    <p>Regular exercise routine</p> Signup and view all the answers

    What is one of the key risk factors for Stress Related Mucosal Damage (SRMD) in an ICU setting?

    <p>Mechanical ventilation for more than 48 hours</p> Signup and view all the answers

    How is Helicobacter pylori typically transmitted?

    <p>Contaminated water</p> Signup and view all the answers

    Which of the following statements about GERD diagnosis is TRUE?

    <p>ALARMD symptoms should be present for endoscopy to be warranted.</p> Signup and view all the answers

    What is a common way in which H. pylori contributes to peptic ulcer disease?

    <p>Producing urease, lipases, and proteases</p> Signup and view all the answers

    What is the main defense mechanism against reflux in Gastroesophageal Reflux Disease (GERD)?

    <p>Lower Esophageal Sphincter (LES) relaxation during swallowing</p> Signup and view all the answers

    Which of the following is NOT a risk factor for Gastroesophageal Reflux Disease (GERD)?

    <p>Recent onset of symptoms (&lt;3 months)</p> Signup and view all the answers

    Which cell type secretes histamine in the stomach and contributes to gastric acid secretion?

    <p>Enterochromaffin-Like (ECL) Cells</p> Signup and view all the answers

    What is the main role of Parietal Cells in the stomach?

    <p>Secretion of gastric acid via H-K-ATPase</p> Signup and view all the answers

    Which of the following medications is NOT listed as a risk factor for Gastroesophageal Reflux Disease (GERD)?

    <p>Potassium Chloride</p> Signup and view all the answers

    What is the acid pH range that activates pepsin from its inactive precursor, pepsinogen?

    <p>$1.5-3.5$</p> Signup and view all the answers

    What is the main function of Surface Mucus Cells in the stomach?

    <p>Secretion of bicarbonate and mucus</p> Signup and view all the answers

    What is the main risk factor for Stress Related Mucosal Damage (SRMD) in an ICU setting?

    <p>Mechanical ventilation over 48 hours</p> Signup and view all the answers

    What is a common method of transmission for H. pylori?

    <p>Fecal-oral transmission</p> Signup and view all the answers

    Which factor contributes to NSAID-induced Peptic Ulcer Disease (PUD)?

    <p>Decreased bicarbonate secretion</p> Signup and view all the answers

    What is a key feature of Helicobacter pylori that aids in its pathogenesis?

    <p>Production of urease</p> Signup and view all the answers

    What is a significant risk factor for Gastroesophageal Reflux Disease (GERD)?

    <p>High alcohol consumption</p> Signup and view all the answers

    Which characteristic is associated with Stress Related Mucosal Damage (SRMD) in an ICU setting?

    <p>High dose steroids use</p> Signup and view all the answers

    What is the main difference between Symptomatic heart burn without injury and with injury?

    <p>The development of esophagitis</p> Signup and view all the answers

    Which condition is characterized by symptoms like cough, laryngitis, and wheezing?

    <p>Barrett’s Esophagus</p> Signup and view all the answers

    What is the underlying cause of Upper GI bleed in Peptic Ulcer Disease (PUD)?

    <p>Ulcerous erosion into an artery</p> Signup and view all the answers

    What contributes to the development of Gastric outlet obstruction in Peptic Ulcer Disease (PUD)?

    <p>Mechanical obstruction caused by scarring</p> Signup and view all the answers

    How do Parietal cells affect ulcer healing in Peptic Ulcer Disease (PUD)?

    <p>Impedes ulcer healing</p> Signup and view all the answers

    Which factor leads to an increased risk of Gastrointestinal Bleeding (GIB) in Peptic Ulcer Disease (PUD)?

    <p>Platelet disaggregation and impaired clot formation</p> Signup and view all the answers

    What is the main defense mechanism that separates the gastric and esophageal lumens from each other?

    <p>Thickening of the smooth muscle lining of the distal esophagus</p> Signup and view all the answers

    Which of the following factors contributes to nocturnal Gastroesophageal Reflux Disease (GERD)?

    <p>Decreased saliva production while sleeping</p> Signup and view all the answers

    What is the main function of Chief Cells in the stomach?

    <p>Synthesizes and secretes pepsinogen</p> Signup and view all the answers

    Which of the following factors can directly irritate the stomach mucosa in Gastroesophageal Reflux Disease (GERD)?

    <p>High fat meals</p> Signup and view all the answers

    What is a common symptom associated with Gastroesophageal Reflux Disease (GERD) that differentiates it from typical symptoms?

    <p>Melena or hematemesis</p> Signup and view all the answers

    Which cell type secretes histamine in the stomach and contributes to gastric acid secretion?

    <p>ECL cells</p> Signup and view all the answers

    What is the main role of Surface Mucus Cells in the stomach?

    <p>Protects the epithelial cell surface with a mucus layer</p> Signup and view all the answers

    How do H2 receptor antagonists (H2RAs) reduce acid secretion?

    <p>By binding to H2 receptors on the basolateral surface of parietal cells</p> Signup and view all the answers

    What is the main therapeutic use of H2 antagonists?

    <p>Treatment of gastric, duodenal, and stress ulcers</p> Signup and view all the answers

    Which drug class blocks acid secretion by inhibiting the H+/K+ ATPase enzyme in parietal cells?

    <p>Proton pump inhibitors</p> Signup and view all the answers

    What is the mechanism of action of H2 receptor antagonists in reducing acid secretion?

    <p>Blocking histamine binding to H2 receptors on parietal cells</p> Signup and view all the answers

    What effect does more frequent initial dosing of proton pump inhibitors (PPIs) have on the time to achieve full inhibition?

    <p>Decreases the time to achieve full inhibition</p> Signup and view all the answers

    What is the main effect of PPIs on acid secretion in the stomach?

    <p>Acid secretion is suppressed for 24-48 hours</p> Signup and view all the answers

    Which ethnic group is more likely to have a CYP2C19 genotype associated with slow metabolism of PPIs?

    <p>Asians</p> Signup and view all the answers

    How do omeprazole and esomeprazole affect the elimination of phenytoin, diazepam, and warfarin in the body?

    <p>Decrease their elimination</p> Signup and view all the answers

    Which of the following is a contraindication for using bismuth subsalicylate?

    <p>Active bleeding ulcer</p> Signup and view all the answers

    What is a potential consequence of high usage of bismuth subsalicylate?

    <p>Salicylate toxicity</p> Signup and view all the answers

    Which medication's effectiveness may be decreased by bismuth subsalicylate?

    <p>Lisinopril</p> Signup and view all the answers

    What can cause harmless darkening of the tongue when using liquid formulations?

    <p>Allergic reaction</p> Signup and view all the answers

    What is the primary function of bismuth subsalicylate when used for the treatment of gastrointestinal symptoms?

    <p>To coat ulcers and erosions as a protective layer</p> Signup and view all the answers

    How is bismuth subsalicylate excreted from the body?

    <p>Minimally absorbed (less than 1%) and excreted in stool</p> Signup and view all the answers

    What warning is associated with bismuth subsalicylate regarding its use?

    <p>It can cause Reye's syndrome if overlapped with other salicylates</p> Signup and view all the answers

    Which of the following is NOT a known function of bismuth subsalicylate?

    <p>Enhance bile secretion</p> Signup and view all the answers

    More Quizzes Like This

    Classifying GERD Syndrome Subtypes
    15 questions

    Classifying GERD Syndrome Subtypes

    SalutaryMinneapolis avatar
    SalutaryMinneapolis
    GERD Symptoms and Patient Teaching
    30 questions

    GERD Symptoms and Patient Teaching

    ToughestAstronomy avatar
    ToughestAstronomy
    GERD Medications and Treatments
    10 questions

    GERD Medications and Treatments

    SustainableAntigorite1088 avatar
    SustainableAntigorite1088
    Understanding GERD
    22 questions

    Understanding GERD

    NeatestPalladium avatar
    NeatestPalladium
    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser