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Questions and Answers
What is the basic unit of inheritance passed from parents to offspring?
What is the basic unit of inheritance passed from parents to offspring?
Which of the following is NOT a base found in DNA?
Which of the following is NOT a base found in DNA?
What is the shape of a DNA molecule?
What is the shape of a DNA molecule?
What are the two components that make up the backbone of a DNA molecule?
What are the two components that make up the backbone of a DNA molecule?
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Which of the following scientists is considered the "Father of Genetics"?
Which of the following scientists is considered the "Father of Genetics"?
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What is the significance of Chargaff's rule in DNA structure?
What is the significance of Chargaff's rule in DNA structure?
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What is the approximate number of protein-coding genes in the human genome?
What is the approximate number of protein-coding genes in the human genome?
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Which of the following is NOT a characteristic typically observed in humans and used for inheritance studies?
Which of the following is NOT a characteristic typically observed in humans and used for inheritance studies?
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What is the genotype of a rabbit that is heterozygous for fur color and homozygous dominant for ear length?
What is the genotype of a rabbit that is heterozygous for fur color and homozygous dominant for ear length?
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When a heterozygous pea plant for both traits is crossed with another heterozygous pea plant, what is the probability of obtaining round seeds?
When a heterozygous pea plant for both traits is crossed with another heterozygous pea plant, what is the probability of obtaining round seeds?
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In the cross between a homozygous recessive rabbit for fur color and a heterozygous rabbit for ear length, what trait cannot be determined?
In the cross between a homozygous recessive rabbit for fur color and a heterozygous rabbit for ear length, what trait cannot be determined?
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Which alleles represent the dominant traits in pea plants according to Mendelian inheritance?
Which alleles represent the dominant traits in pea plants according to Mendelian inheritance?
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What field can genetics be applied to for improving food security?
What field can genetics be applied to for improving food security?
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What is the significance of the Law of Dominance in Mendelian genetics?
What is the significance of the Law of Dominance in Mendelian genetics?
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According to the Law of Segregation, what happens to alleles during gamete formation?
According to the Law of Segregation, what happens to alleles during gamete formation?
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What does the Law of Independent Assortment imply?
What does the Law of Independent Assortment imply?
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What is the genotype of a heterozygous tall pea plant?
What is the genotype of a heterozygous tall pea plant?
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In a monohybrid cross, what does a Punnett square represent?
In a monohybrid cross, what does a Punnett square represent?
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If a homozygous black-haired father (AA) and a heterozygous black-haired mother (Aa) have children, which phenotype will be the least likely among the offspring?
If a homozygous black-haired father (AA) and a heterozygous black-haired mother (Aa) have children, which phenotype will be the least likely among the offspring?
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Which of the following correctly identifies the genotypic ratio from a monohybrid cross involving two heterozygous parents?
Which of the following correctly identifies the genotypic ratio from a monohybrid cross involving two heterozygous parents?
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In a case where a mother has genotype Bb for eye color and a father has genotype bb, what are the possible genotypes for their child?
In a case where a mother has genotype Bb for eye color and a father has genotype bb, what are the possible genotypes for their child?
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What phenotype ratio can be expected from a monohybrid cross between two heterozygous yellow (Yy) flower plants?
What phenotype ratio can be expected from a monohybrid cross between two heterozygous yellow (Yy) flower plants?
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When performing a dihybrid cross, what is the first step?
When performing a dihybrid cross, what is the first step?
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How are dominant and recessive alleles represented in a Punnett square?
How are dominant and recessive alleles represented in a Punnett square?
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What is the phenotypic ratio expected when crossing a heterozygous tall plant with a short plant?
What is the phenotypic ratio expected when crossing a heterozygous tall plant with a short plant?
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Which of the following traits is considered dominant in the described mouse traits?
Which of the following traits is considered dominant in the described mouse traits?
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What does a homozygous genotype imply about the alleles present?
What does a homozygous genotype imply about the alleles present?
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Which of the following describes a dihybrid cross?
Which of the following describes a dihybrid cross?
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In the context of fur color in rabbits, which genotype will produce white-furred offspring?
In the context of fur color in rabbits, which genotype will produce white-furred offspring?
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What would be the result if a homozygous running mouse is crossed with a heterozygous running mouse?
What would be the result if a homozygous running mouse is crossed with a heterozygous running mouse?
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If a child has a genotype of dd for hair color, what must one parent’s genotype be?
If a child has a genotype of dd for hair color, what must one parent’s genotype be?
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Which step follows after determining the possible gamete combinations in a dihybrid cross?
Which step follows after determining the possible gamete combinations in a dihybrid cross?
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Flashcards
Heterozygous
Heterozygous
An organism with two different alleles for a trait (e.g., Rr).
Homozygous
Homozygous
An organism with two identical alleles for a trait (e.g., RR or rr).
Mendelian inheritance
Mendelian inheritance
The patterns of inheritance first described by Gregor Mendel, explaining how traits are passed from parents to offspring.
Probability of offspring traits
Probability of offspring traits
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Dominant and recessive alleles
Dominant and recessive alleles
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Law of Dominance
Law of Dominance
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Law of Segregation
Law of Segregation
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Law of Independent Assortment
Law of Independent Assortment
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Monohybrid Cross
Monohybrid Cross
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Punnett Square
Punnett Square
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Genotypic Ratio (GR)
Genotypic Ratio (GR)
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Phenotypic Ratio (PR)
Phenotypic Ratio (PR)
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Homozygous Allele
Homozygous Allele
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Heterozygous Allele
Heterozygous Allele
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Dihybrid Experiment
Dihybrid Experiment
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Dominant allele
Dominant allele
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Recessive allele
Recessive allele
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Genotypic ratio
Genotypic ratio
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Phenotypic ratio
Phenotypic ratio
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Dihybrid cross
Dihybrid cross
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Gamete combinations
Gamete combinations
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Trait inheritance
Trait inheritance
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Genetics
Genetics
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Gene
Gene
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DNA
DNA
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Base pairs
Base pairs
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Nucleotide
Nucleotide
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Double helix
Double helix
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Mendelian Laws of Inheritance
Mendelian Laws of Inheritance
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Erwin Chargaff
Erwin Chargaff
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Study Notes
Introduction to Genetics
- Genetics is the scientific study of genes and heredity, exploring how DNA variations influence traits passed down.
- It's a branch of biology, focusing on the DNA of organisms, its expression as genes, and inheritance patterns.
Learning Targets
- Students will understand Mendelian Laws of Inheritance.
- The process of predicting offspring genotypes and phenotypes will be demonstrated.
Preliminary Activity
- Students should check with their seatmates on traits, for example, tongue rolling ability, earlobe attachment, hair line type, and dimples presence.
Traits
- Ability to roll tongue
- Attached or detached earlobes
- Straight hair line or widow’s peak
- Dimples or no dimples
What is Genetics?
- Genetics examines how variations in DNA sequence lead to specific traits.
- These passed-down traits are often the result of DNA sequence variations.
Vocabulary
- The slides show examples of relevant vocabulary words related to genetics.
Genetics
- Genetics is the study of genes and how they play a role in heredity.
Genes
- Genes are units of heredity, composed of DNA molecules that pass traits from parents to offspring.
- The human genome comprises approximately 20,000 protein-coding genes.
Gene
- A gene is the fundamental unit of inheritance.
- It is passed from parents to offspring, carrying instructions for physical and biological traits.
- Genes, part of the genome, encode the information necessary for protein synthesis.
- Genes are made up of DNA.
DNA
- DNA is primarily located in the cell nucleus.
- DNA serves as a code composed of four chemical bases: adenine (A), guanine (G), cytosine (C), and thymine (T).
- Complementary base pairing links A to T, and C to G. Each base is attached to a sugar molecule.
- DNA's structure is a double helix made up of paired nucleotides.
DNA
- DNA's structure consists of an alternating sugar-phosphate backbone.
- Erwin Chargaff's findings in biochemistry show that adenine percentage equals thymine, and guanine equals cytosine.
DNA (continued)
- A nucleotide is a combined structure of a base, sugar, and phosphate.
- Nucleotides form paired strands creating a double helix.
Important Terms to Remember
- Allele: An alternative form of a gene.
- Dominant trait: A trait always expressed if present.
- F₁ generation: The first generation of offspring.
- F₂ generation: The second generation of offspring arising from interbreeding F₁ individuals.
- Gamete: A reproductive cell.
- Genotype: The genetic makeup of an individual.
- Heterozygous: Having different alleles for a given trait.
- Homozygous: Having identical alleles for a given trait.
- Phenotype: The observable characteristics of an individual.
- Punnett square: A diagram used to predict the outcome of a genetic cross.
- Recessive trait: A trait masked by a dominant trait.
Brief History of Genetics
- Gregor Mendel's experiments with peas over eight years (1856-1863) laid the foundation for genetics.
- He documented 10,000 pea plants, tracking generational traits.
Gregor Mendel
- Born in 1822 in Czechoslovakia, Mendel later became a monk.
- His studies encompassed biology and statistics.
- Mendel studied at the University of Vienna.
Mendel Continued
- Mendel's experiments involved approximately 28,000 pea plants.
Why Peas?
- Peas were chosen for Mendel's experiments due to their ease of growth.
- Observable traits made identification simple.
- A large sample size permitted comprehensive analysis.
Characteristics of Garden Peas Studied by Mendel
- Traits like seed color, seed shape, seed coat color, flower position, stem length, pod color, and pod shape were studied.
Gregor Johann Mendel
- Mendel's work formulated the laws of inheritance, including the Law of Dominance, Segregation, and Independent Assortment.
Law of Dominance
- A trait is considered dominant if its expression overrides another (recessive) allele.
- A dominant trait always manifests even if a recessive one is present.
- An organism expressing a dominant trait is always visible.
- Conversely, a recessive allele is only expressed if the dominant one isn't present.
Law of Segregation
- Each individual has a pair of alleles for each trait that separates during gamete formation.
- Each gamete receives just one allele from each trait.
- Allele allocation from parents to offspring is random.
- Separation of alleles occurs during gamete formation.
Law of Independent Assortment
- Alleles for different traits segregate independently during gamete formation.
- The inheritance of a trait isn't influenced by others.
Law of Independent Assortment
- Traits, such as freckles and curly hair, are inherited independently, not connected.
Law of Dominance
- Dominance signifies an allele's capacity to express itself in the presence of another allele for the same trait.
- Some alleles are dominant, prevailing over others that are recessive.
Law of Dominance (continued)
- An organism with a dominant allele for a specific trait always expresses that trait.
Law of Dominance (continued)
- Recessive traits express themselves only in the absence of a dominant allele.
Mendelian Laws Through Punnett Square
- A Punnett Square illustrates possible gene combinations in offspring.
- Dominant alleles are denoted by capital letters, while recessive ones are lowercase.
Monohybrid Cross
- A monohybrid cross examines the inheritance of a single trait.
- Each square represents a 25% chance for a specific genotype and phenotype of an offspring.
Example
- The allele for yellow flowers is dominant over the allele for green flowers.
Example (continued)
- Both parents in the example have heterozygous alleles for yellow flowers.
Example (continued)
- Ratios of genotypes and phenotypes in offspring will be identified, such as 1:2:1 for genotypes (YY, Yy, yy) and 3:1 for phenotypes (yellow, green).
Sample Problem
- A problem, likely involving pea plants or mice, is presented for determining genotypic and phenotypic ratios via Punnett Squares.
Dihybrid Cross
- A dihybrid cross investigates the inheritance of two traits.
- It analyzes how parents with contrasting traits influence their offspring's genotypes and phenotypes.
- An example would be observing traits like black hair vs blonde hair and blue eyes vs brown eyes.
Steps in Doing a Dihybrid Cross
- Identify the genotypes of the parents in a dihybrid cross.
- Determine possible gamete combinations from each parent for each trait.
- Create a Punnett Square to visualize possible combinations for the trait in the offspring.
- Determine genotypes and phenotypes of potential offspring.
- Calculate genotypic and phenotypic ratios for offspring.
Sample Problem (1)
- Scenarios on parentage disputes, examining if the child in question can be truly attributed to a declared father.
Sample Problem (2)
- Another case, focused on a child with a specific trait, determines if the child is biologically related to a declared parent.
Sample Problem (3)
- A problem involving mice and their color/running traits will determine the genotypic and phenotypic ratios based on their traits.
Sample Problem (4)
- A problem involving rabbits discusses their fur color and ear length characteristics, analyzing the likelihood of offspring inheriting these attributes.
Sample Problem (5)
- A pea plant example highlights the inheritance of seed traits, identifying offspring probabilities given particular parental traits.
Let's Apply It!
- This section demonstrates the application of Mendelian Laws across various fields relevant to genetics.
Instructions
- Guidance for tasks likely involving partner work, research, and infographic creation.
Mendelian Laws on Real-life / Social Context
- Different areas of application for Mendelian laws, such as healthcare, agricultural practices, and conservation biology.
Resource Page
- Examples include images or illustrations of a variety of situations and concepts related to the subject matter.
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Description
Test your understanding of fundamental genetics concepts in this quiz. Answer questions about inheritance, DNA structure, and key figures in genetics. This quiz will challenge your knowledge and deepen your understanding of genetic principles.