Genetics of Sex Determination in Mammals
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Questions and Answers

What is the characteristic of the X and Y chromosomes during meiosis in male mammals?

  • They are identical and behave like autosomes.
  • They are fully homologous and undergo crossing-over freely.
  • They are partially homologous and crossing-over is restricted to pseudoautosomal regions. (correct)
  • They are completely non-homologous and do not pair during meiosis.

What is the sex determination system in birds and some reptiles?

  • XY system, where males are XX and females are XY.
  • XX system, where males are XY and females are XX.
  • YW system, where males are YY and females are YW.
  • ZW system, where males are ZZ and females are ZW. (correct)

In mammals, what is the percentage of male gametes that contain an X chromosome?

  • 100%
  • 50% (correct)
  • 25%
  • 75%

What is the behavior of the two X chromosomes in female mammals during meiosis?

<p>They are homologous and behave like autosomes. (D)</p> Signup and view all the answers

What is the term for the regions of the X and Y chromosomes where crossing-over occurs during prophase I of meiosis?

<p>Pseudoautosomal regions (B)</p> Signup and view all the answers

What is the primary function of the testis-determining factor TDF protein?

<p>To signal male development in mammals (A)</p> Signup and view all the answers

Which of the following statements about the X and Y chromosomes in mammals is TRUE?

<p>Short segments at either end of the Y chromosome are homologous with regions on the X chromosome (A)</p> Signup and view all the answers

During meiosis in the ovaries, what is the resulting number of sex chromosomes in each gamete?

<p>One X chromosome (C)</p> Signup and view all the answers

In mammals, which of the following is responsible for determining the sex of an individual?

<p>The presence of the Y chromosome (C)</p> Signup and view all the answers

What is the approximate length of the human X chromosome?

<p>156.0 Mb (C)</p> Signup and view all the answers

What is the primary function of the SRY gene in mammals?

<p>Encoding the testis-determining factor protein for male development (D)</p> Signup and view all the answers

What is the outcome of crossing-over between X and Y chromosomes in humans?

<p>Genetic variation in the offspring through recombination of PARs (D)</p> Signup and view all the answers

What is the significance of the pseudoautosomal regions (PARs) in sex determination?

<p>PARs facilitate synapsis and crossing-over between X and Y chromosomes (C)</p> Signup and view all the answers

What is the chromosomal composition of a zygote formed from a 44+ XY sperm and a 44+ XX ovum?

<p>44+ XY (B)</p> Signup and view all the answers

What is the result of introducing an SRY transgene into a chromosomally female mouse?

<p>A male mouse indistinguishable from a normal XY male (C)</p> Signup and view all the answers

What is the genotype of a male who expresses an X-linked recessive trait?

<p>Xa (D)</p> Signup and view all the answers

A female is a carrier of an X-linked recessive trait. What is the probability that her sons will express the trait?

<p>50% (D)</p> Signup and view all the answers

A male has an X-linked dominant trait. What is the probability that his daughters will inherit the trait?

<p>100% (C)</p> Signup and view all the answers

What is the genotype of a female who expresses an X-linked recessive trait?

<p>Xa Xa (A)</p> Signup and view all the answers

A female is homozygous for an X-linked dominant allele. What is the probability that her sons will inherit the dominant allele?

<p>50% (B)</p> Signup and view all the answers

What is the significance of sister chromatids forming chiasmata in the same homologous chromosome?

<p>It has no genetic consequences (C)</p> Signup and view all the answers

What is the purpose of determining the recombination rate in Drosophila melanogaster crosses?

<p>To produce a genetic map of genes on a chromosome (B)</p> Signup and view all the answers

What is the symbol 'b' representing in the given cross?

<p>A mutant allele for body colour (A)</p> Signup and view all the answers

What is the genetic consequence of recombination between linked genes?

<p>It produces recombinant offspring (A)</p> Signup and view all the answers

What is the relative position of the three genes on the chromosome?

<p>The order of the genes cannot be determined from the given data (D)</p> Signup and view all the answers

What is the fundamental concept underlying the chromosomal basis of inheritance?

<p>Genes are DNA sequence segments located on chromosomes (C)</p> Signup and view all the answers

Who is credited with providing the first solid evidence that genes are located on specific chromosomes?

<p>Thomas Hunt Morgan (A)</p> Signup and view all the answers

What is the relationship between genes and alleles?

<p>Alleles are variations of genes (A)</p> Signup and view all the answers

What is the significance of homologous chromosomes in the context of gene inheritance?

<p>They are involved in the transmission of genetic traits from one generation to the next (C)</p> Signup and view all the answers

What is the primary conclusion that can be drawn from the chromosomal basis of Mendel's laws?

<p>Genes are DNA sequence segments located on chromosomes (A)</p> Signup and view all the answers

What was the species of fruit fly used by Morgan in his experiments?

<p>Drosophila melanogaster (A)</p> Signup and view all the answers

What is the sex chromosome constitution of a male fruit fly?

<p>XY (A)</p> Signup and view all the answers

What is the total number of chromosomes in a fruit fly cell?

<p>8 (C)</p> Signup and view all the answers

Why are fruit flies used as an ideal experimental organism for genetics?

<p>All of the above (D)</p> Signup and view all the answers

What was the title of Morgan's 1915 publication?

<p>The Mechanism of Mendelian Heredity (C)</p> Signup and view all the answers

What was the significance of Morgan's experiments with Drosophila melanogaster?

<p>They showed that genes are located on chromosomes (C)</p> Signup and view all the answers

In what year was Morgan awarded the Nobel Prize in Physiology or Medicine?

<p>1933 (C)</p> Signup and view all the answers

What is the number of autosome pairs in a fruit fly?

<p>3 (C)</p> Signup and view all the answers

What is the sex chromosome constitution of a female fruit fly?

<p>XX (D)</p> Signup and view all the answers

How often can a new generation of fruit flies be bred?

<p>Every two weeks (B)</p> Signup and view all the answers

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