Genetics in Dental Education
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Questions and Answers

What genetic mutation is associated with familial tooth agenesis and colorectal cancer?

  • AXIN2 mutations (correct)
  • FGF3 mutations
  • TP53 mutations
  • BRCA1 mutations

    • Which publication discusses the implications of genetics for clinical dental practice?

  • American Journal of Human Genetics
  • BMC Medical Genetics
  • Journal of Dental Education (correct)
  • Genetics in Medicine

    • Which organization provided recommendations for enhancing oversight of genetic tests?

  • NIH
  • NCHPEG
  • CDC
  • SACGT (correct)

    • What year was the third edition of Core Competencies in Genetics for Health Care Professionals published?

    <p>2007</p> Signup and view all the answers

    Which genetic condition is indicated by variable expressivity in the context provided?

    <p>LAMM syndrome</p> Signup and view all the answers

    What is the primary reason for incorporating genetics into dental school curricula?

    <p>To assist in making accurate dental diagnoses</p> Signup and view all the answers

    As of 2014, how many dental schools in the United States required genetics prior to admission?

    <p>No schools</p> Signup and view all the answers

    Which disorder is NOT listed as a multifactorial trait associated with oral health?

    <p>Amelogenesis imperfecta</p> Signup and view all the answers

    What type of disorders did the authors mention as impacting oral health?

    <p>Cytogenetic disorders and multifactorial traits</p> Signup and view all the answers

    What notable change was observed in dental school curricula regarding human genetics by 2001?

    <p>Eight out of 53 schools had a formal genetics course.</p> Signup and view all the answers

    Why is taking a family history important in genetic assessment for dental health?

    <p>It aids in the diagnosis by constructing a three-generation pedigree.</p> Signup and view all the answers

    Which gene disorder associated with oral health is mentioned in the commentary?

    <p>Amelogenesis imperfecta</p> Signup and view all the answers

    What is the stance of professional organizations on teaching genetics in dental schools?

    <p>They advocate for its inclusion in the curriculum.</p> Signup and view all the answers

    What percentage of dental students correctly diagnosed the genetic condition after patient-educator teaching?

    <p>83%</p> Signup and view all the answers

    What is one proposed benefit of increased education in genetics for dental health professionals?

    <p>Improved diagnostic skills</p> Signup and view all the answers

    Which genetic condition is associated with the COL1A1 mutation (G559C)?

    <p>Mild osteogenesis imperfecta</p> Signup and view all the answers

    Which genetic disorder is referenced in the study regarding autosomal recessive mutations?

    <p>Nephrocalcinosis</p> Signup and view all the answers

    Which study emphasizes the impact of patient-educators on basic science courses in dental education?

    <p>Study of the impacts of patient-educators</p> Signup and view all the answers

    What is a suggested benefit of biannual dental visits in relation to genetic testing?

    <p>Prevention of tooth loss</p> Signup and view all the answers

    What is the main focus of the authors Collins and Tabak's 2004 report?

    <p>Importance of genetics education</p> Signup and view all the answers

    What does the article suggest about interprofessional collaboration in genetics?

    <p>It is essential for improved outcomes</p> Signup and view all the answers

    According to the study, what percentage of dental professionals may not have effectively utilized genetic tests?

    <p>83%</p> Signup and view all the answers

    What genetic condition has been associated with mutations in the ANIX2 gene?

    <p>Oligodontia</p> Signup and view all the answers

    Which professional should a dentist refer an oligodontia patient to if there is a family history of colorectal cancer?

    <p>Clinical geneticist</p> Signup and view all the answers

    Why is it important for dentists to have an understanding of genetics?

    <p>To interact effectively with the health care team</p> Signup and view all the answers

    What is a limitation of genetics education among dentists mentioned?

    <p>Isolation from other health care disciplines</p> Signup and view all the answers

    What type of genetic tests are considered neither clinically valid nor useful?

    <p>Tests for small effect SNP variants</p> Signup and view all the answers

    What is a requirement for dental graduates according to the provided information?

    <p>Possess basic genetics knowledge and skills</p> Signup and view all the answers

    Which aspect complicates the interaction between dentistry and other health care fields?

    <p>Separate health care records</p> Signup and view all the answers

    What is a primary reason for the integration of patient-educators in dental schools?

    <p>To enhance student interactions with patients</p> Signup and view all the answers

    What is the main objective of educating dentists about genetics?

    <p>To strengthen collaborative care with other health professionals</p> Signup and view all the answers

    How many genetic tests are currently available, encompassing various genetic disease types?

    <p>More than 3,000</p> Signup and view all the answers

    Which dental phenotype is associated with FAM20A mutations?

    <p>Amelogenesis imperfecta</p> Signup and view all the answers

    What type of inheritance pattern is associated with the FAM20A gene?

    <p>Autosomal Recessive</p> Signup and view all the answers

    Which of the following conditions can be associated with enamel defects?

    <p>Kidney disease</p> Signup and view all the answers

    What is the likely psychosocial impact of dental disorders?

    <p>Cosmetic concerns and stigmatization</p> Signup and view all the answers

    Nephrocalcinosis in children is typically described as:

    <p>Clinically asymptomatic</p> Signup and view all the answers

    What is an associated complication of colon cancer indicated by missing teeth?

    <p>Liver disease</p> Signup and view all the answers

    How does the involvement of patient-educators impact student learning?

    <p>Enhances empathy and learning speed</p> Signup and view all the answers

    Which condition is NOT linked with enamel defects according to recent studies?

    <p>Cardiovascular disease</p> Signup and view all the answers

    Which gene is primarily associated with renal syndrome related to dental features?

    <p>FAM20A</p> Signup and view all the answers

    Which genetic condition is indicated by microdontia and possibly linked to hearing impairment?

    <p>Microdeletion syndrome</p> Signup and view all the answers

    What is the primary role of DNA in living organisms?

    <p>To store genetic information.</p> Signup and view all the answers

    What is the main focus of genetics?

    <p>Study of genes</p> Signup and view all the answers

    All living organisms reproduce asexually.

    <p>False</p> Signup and view all the answers

    What project mapped every chromosome of humans?

    <p>The Human Genome Project.</p> Signup and view all the answers

    The process by which organisms inherit traits from their parents is called ______.

    <p>inheritance</p> Signup and view all the answers

    Which of these statements about reproduction is true?

    <p>Human beings reproduce sexually.</p> Signup and view all the answers

    The study of genetics has no impact on medical science.

    <p>False</p> Signup and view all the answers

    What type of inheritance includes traits linked to sex chromosomes?

    <p>Sex-linked inheritance.</p> Signup and view all the answers

    Study Notes

    Genetics and Genomics in Dental Curricula

    • The current dental school curriculum in the US lacks a sufficient focus on human genetics and genomics.
    • In 2001, only 8 of 53 U.S. dental schools had a formal course in human genetics.
    • Only one dental school, the University of Florida, mandates a semester of molecular biology or genetics for admission.
    • The authors advocate for incorporating genetics and genomics into dental education as it is relevant to diagnosis, treatment, and patient education.
    • Dental practitioners encounter patients with genetic disorders that can affect oral health.
    • Examples provided include: amelogenesis imperfecta, cystic fibrosis, Smith–Magenis syndrome, Williams syndrome, cleft lip/cleft palate, and diabetes.
    • Dental phenotypes can signal systemic manifestations, requiring referral to other specialists.
    • Understanding genetics helps dentists provide comprehensive patient care, including family history, genetic testing, and referral when necessary.
    • A strong understanding of genetics is crucial for interpreting genetic test results, particularly in the context of predicting risk for common, complex diseases.
    • The authors emphasize the need for dentists to be knowledgeable about genetic resources and be able to collaborate with other healthcare professionals in a personalized medicine approach.

    The Importance of Patient-Educators

    • Patient-educators play a vital role in conveying the psychosocial aspects of genetic disorders to dental students.
    • The use of patient-educators has been shown to improve student understanding and empathy.
    • Integrating patient-educators in dental schools is an essential part of promoting patient-centered care.

    The Need for Interprofessional Collaboration

    • Limited genetic education restricts dentists' ability to effectively interact with other healthcare professionals.
    • This isolation is further exacerbated by separate health care records and different reimbursement systems.
    • Integration of genetics into dental training enhances interprofessional communication and improves patient outcomes.

    Key Takeaway

    • Graduating dentists should possess basic genetics knowledge and skills to integrate genetic concepts into their practice.
    • The development of specific core competencies in genetics is necessary to achieve this goal.
    • Greater emphasis on genetics and genomics in dental school curricula is crucial for promoting evidence-based, comprehensive dental care.

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    Related Documents

    Hart and Hart (2016) Human Genetics in Dental School PDF
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    Description

    This quiz explores the integration of genetics and genomics in dental curricula. It highlights the current shortcomings in dental education regarding human genetics and emphasizes its importance for diagnosis and treatment of genetic disorders in patients. Understanding genetics enhances the capabilities of dental practitioners in providing comprehensive care.

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