Genetic Variants Overview

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Questions and Answers

What characterizes inherited gene variants or mutations?

  • They can only be expressed if the individual is homozygous for the trait.
  • They result from errors during DNA replication in somatic cells.
  • They can be present from birth and passed from parent to child. (correct)
  • They occur during an individual's lifetime due to environmental factors.

Which statement is true regarding non-inherited gene variants?

  • They can be passed to the next generation if they occur in germ cells.
  • They are always expressed phenotypically regardless of the gene type.
  • They cannot be passed to children and occur in somatic cells. (correct)
  • They result from inherited mutations that manifest later in life.

What environmental factor can cause non-inherited gene variants?

  • Exposure to UV radiation from the sun. (correct)
  • A viral infection during childhood.
  • Genetic drift over several generations.
  • Inherited recessive traits from ancestors.

How can a recessive gene variant influence phenotype expression?

<p>The phenotype can be expressed in individuals with a dominant allele. (A)</p> Signup and view all the answers

Which of the following best describes a somatic variant?

<p>A variant that occurs after fertilization and affects somatic cells. (C)</p> Signup and view all the answers

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Study Notes

Genetic Variants

  • Genetic variants can be inherited or occur spontaneously.
  • Inherited variants are passed from a parent to their offspring.
  • Individuals may be carriers of a variant gene but not express the associated phenotype if the variant is recessive.
  • Non-inherited variants, also known as somatic variants, occur in somatic cells during an individual's lifetime.
  • Somatic variants cannot be passed down to offspring.
  • Environmental factors, such as exposure to radiation (X-rays or UV light), can contribute to non-inherited variants.
  • Errors during DNA replication during cell division can also lead to non-inherited variants.

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