Podcast
Questions and Answers
Which gene mutation accounts for approximately half of early-onset Alzheimer Disease cases?
Which gene mutation accounts for approximately half of early-onset Alzheimer Disease cases?
- Hepatocyte nuclear factor 1-α (HNF1α)
- Insulin promoter factor 1 (IPF1)
- Presenilin 1 (correct)
- KCNJ11
Which of the following genes is involved in adipocyte differentiation and increases the risk of Type II Diabetes by 25%?
Which of the following genes is involved in adipocyte differentiation and increases the risk of Type II Diabetes by 25%?
- Hepatic nuclear factor 1-ß (HNF1ß)
- PPAR-gamma (correct)
- Neurogenic differentiation 1 (NEUROD1)
- TCF7L2
What is the recurrence risk of Type I diabetes if a sibling shares the HLA DR3 or DR4 gene?
What is the recurrence risk of Type I diabetes if a sibling shares the HLA DR3 or DR4 gene?
- 20% (correct)
- 10-15%
- 50%
- 100%
What is the heritability range for obesity, as mentioned in the text?
What is the heritability range for obesity, as mentioned in the text?
Which gene mutation is responsible for approximately 50% of MODY cases?
Which gene mutation is responsible for approximately 50% of MODY cases?
What is the most significant transcription factor involved in secreting insulin and linked to a 50% increase in risk of Type II Diabetes?
What is the most significant transcription factor involved in secreting insulin and linked to a 50% increase in risk of Type II Diabetes?
What is the approximate percentage of Type II Diabetes cases that are increasing in younger people in affluent areas?
What is the approximate percentage of Type II Diabetes cases that are increasing in younger people in affluent areas?
What is the risk of Alzheimer Disease if a person has an affected first-degree relative, according to the text?
What is the risk of Alzheimer Disease if a person has an affected first-degree relative, according to the text?
Which gene mutation is implicated in clearance of amyloid from the brain and can increase the risk of Alzheimer Disease in certain populations?
Which gene mutation is implicated in clearance of amyloid from the brain and can increase the risk of Alzheimer Disease in certain populations?
