Genetic Lineage Markers Quiz

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Questions and Answers

In forensic casework on sexual assault evidence, what is the advantage of using male-specific amplification?

  • It leads to a higher power of discrimination due to genetic shuffling with recombination
  • It allows for the generation of rare random match probabilities using the product rule
  • Lower levels of male perpetrator DNA can be recovered due to concern about heterozygote allele loss
  • It can potentially recover results with lower levels of male perpetrator DNA without concern about heterozygote allele loss (correct)

Why is Y-specific DNA useful in deficiency paternity cases?

  • It provides a higher power of discrimination due to genetic shuffling with recombination
  • It allows for the determination of the number of male contributors quickly
  • It has a fairly high mutation rate similar to autosomes
  • It can be used to tie male children to fathers in motherless paternity cases (correct)

What is a disadvantage of Y-specific DNA in forensic kits with Y STR markers?

  • It allows for the determination of the number of male contributors quickly
  • Loci are independent of one another, allowing for rare random match probabilities
  • It cannot generate rare random match probabilities using the product rule (correct)
  • It provides a higher power of discrimination due to genetic shuffling with recombination

Why are family members likely to have indistinguishable haplotypes with Y-specific DNA?

<p>Unless mutations have occurred, leading to 'family' identification (A)</p> Signup and view all the answers

What is the potential benefit of using Y-specific DNA in missing persons investigations?

<p>Patrilineal male relatives may be used for reference samples (D)</p> Signup and view all the answers

In forensic casework on sexual assault evidence, what is a potential advantage of using male-specific amplification?

<p>To determine the number of male contributors quickly (B)</p> Signup and view all the answers

What is a disadvantage of Y-specific DNA in forensic kits with Y STR markers?

<p>Independence of loci, leading to rare random match probabilities (C)</p> Signup and view all the answers

What is the potential benefit of using Y-specific DNA in missing persons investigations?

<p>Ability to tie male children to fathers in motherless paternity cases (C)</p> Signup and view all the answers

Why is Y-specific DNA useful in deficiency paternity cases?

<p>To tie male children to fathers in motherless paternity cases (C)</p> Signup and view all the answers

Why are family members likely to have indistinguishable haplotypes with Y-specific DNA?

<p>Due to the ability to use haplotypes for family identification (C)</p> Signup and view all the answers

In forensic casework on sexual assault evidence, what is a potential disadvantage of using Y-specific DNA?

<p>Lower power of discrimination due to genetic shuffling with recombination (D)</p> Signup and view all the answers

What is a potential drawback of using male-specific amplification in forensic casework on sexual assault evidence?

<p>Concern about heterozygote allele loss via stochastic PCR amplification (B)</p> Signup and view all the answers

Why is Y-specific DNA useful in deficiency paternity cases?

<p>Tying male children to fathers in motherless paternity cases (A)</p> Signup and view all the answers

What is a potential benefit of using Y-specific DNA in missing persons investigations?

<p>Ability to use patrilineal male relatives for reference samples (C)</p> Signup and view all the answers

What is a potential drawback of Y-specific DNA in forensic kits with Y STR markers?

<p>Indistinguishable haplotypes among family members unless mutations have occurred (C)</p> Signup and view all the answers

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