Podcast
Questions and Answers
Which of the following is a characteristic of Osteogenesis Imperfecta?
Which of the following is a characteristic of Osteogenesis Imperfecta?
- Long arms and legs
- Multipl impacted teeth
- Brown or purple colored teeth (correct)
- Curvature of the spine
What is a potential issue during dental surgery for patients with Osteopetrosis?
What is a potential issue during dental surgery for patients with Osteopetrosis?
- Increased risk of bony fractures (correct)
- Inability to anesthetize
- Poor tooth alignment
- High risk of dental decay
Which of the following symptoms is associated with Marfan Syndrome?
Which of the following symptoms is associated with Marfan Syndrome?
- Persistent primary teeth
- Soft dentin
- Multiple supernumerary teeth
- Flexible joints (correct)
What dental issue may occur in Cleidocranial Dysostosis?
What dental issue may occur in Cleidocranial Dysostosis?
What characteristic change is typical in the bones of someone with Osteopetrosis?
What characteristic change is typical in the bones of someone with Osteopetrosis?
What are the classical deformities associated with rheumatoid arthritis?
What are the classical deformities associated with rheumatoid arthritis?
Which of the following is a common dermatological manifestation in rheumatoid arthritis?
Which of the following is a common dermatological manifestation in rheumatoid arthritis?
What complication can arise from the use of NSAIDs in rheumatoid arthritis treatment?
What complication can arise from the use of NSAIDs in rheumatoid arthritis treatment?
What is the duration of the 1st incubation period for syphilitic chancre after the spirochet introduction?
What is the duration of the 1st incubation period for syphilitic chancre after the spirochet introduction?
Which period follows the appearance of the chancre and lasts for 6 weeks?
Which period follows the appearance of the chancre and lasts for 6 weeks?
What syndrome may cause splenomegaly and leukopenia in rheumatoid arthritis?
What syndrome may cause splenomegaly and leukopenia in rheumatoid arthritis?
During which period do serological reactions become positive for the first time after chancre removal?
During which period do serological reactions become positive for the first time after chancre removal?
Which of the following is NOT a cardiovascular complication of rheumatoid arthritis?
Which of the following is NOT a cardiovascular complication of rheumatoid arthritis?
Which imaging technique is valuable for early diagnosis and follow-up of joint damage in rheumatoid arthritis?
Which imaging technique is valuable for early diagnosis and follow-up of joint damage in rheumatoid arthritis?
How long does the second cycle of acquired syphilis last on average?
How long does the second cycle of acquired syphilis last on average?
What is defined as Latent Syphilis?
What is defined as Latent Syphilis?
Which condition is described as an autoimmune disease that primarily affects the skin and muscles?
Which condition is described as an autoimmune disease that primarily affects the skin and muscles?
What is the most common type of lupus affecting multiple organ systems?
What is the most common type of lupus affecting multiple organ systems?
Which classification refers to early congenital syphilis?
Which classification refers to early congenital syphilis?
What is the average duration of the 3rd Period of acquired syphilis?
What is the average duration of the 3rd Period of acquired syphilis?
What type of syphilis occurs as a result of blood transfusion contamination?
What type of syphilis occurs as a result of blood transfusion contamination?
What is the appearance of the chancre in its early stages?
What is the appearance of the chancre in its early stages?
How does a chancre develop over time?
How does a chancre develop over time?
What is described as Chancre Immunity?
What is described as Chancre Immunity?
Where is the chancre most commonly located in males?
Where is the chancre most commonly located in males?
What occurs approximately 8-10 days after the appearance of a chancre?
What occurs approximately 8-10 days after the appearance of a chancre?
What symptoms may occur during the second cycle of syphilis?
What symptoms may occur during the second cycle of syphilis?
What type of lymphadenopathy is associated with second cycle syphilis?
What type of lymphadenopathy is associated with second cycle syphilis?
How long does a chancre typically take to heal without secondary infection?
How long does a chancre typically take to heal without secondary infection?
What is a common oral complication associated with HIV infection?
What is a common oral complication associated with HIV infection?
Which symptom is NOT commonly associated with HIV/AIDS?
Which symptom is NOT commonly associated with HIV/AIDS?
What dental condition is commonly seen as a side effect of the anticonvulsant medication phenytoin?
What dental condition is commonly seen as a side effect of the anticonvulsant medication phenytoin?
Which condition is a primary concern for a dental practitioner treating a patient with myasthenia gravis?
Which condition is a primary concern for a dental practitioner treating a patient with myasthenia gravis?
What is a primary neurological symptom of Parkinson's disease that can impact dental care?
What is a primary neurological symptom of Parkinson's disease that can impact dental care?
What is an inappropriate medication for a patient with myasthenia gravis?
What is an inappropriate medication for a patient with myasthenia gravis?
What type of infections are particularly common in individuals with HIV late-stage manifestations?
What type of infections are particularly common in individuals with HIV late-stage manifestations?
Which neurological disorder is characterized by demyelinated plaques in the central nervous system?
Which neurological disorder is characterized by demyelinated plaques in the central nervous system?
Study Notes
Osteogenesis Imperfecta
- Avoid pressure during dental surgery
- Dentinogenesis Imperfecta: soft dentin, brown/purple teeth
Cleidocranial Dysostosis
- Multiple supernumerary teeth
- Multiple impacted teeth
- Persistent/depressed primary teeth
- Crown/root malformations
- Dentigerous cysts
Osteopetrosis
- Increased density of skull bones
- Widened face
- Superiorly located nose tip
- Trigeminal/facial neuropathy
- Osteomyelitis due to tooth extractions/bony fractures
Marfan Syndrome
- Cardiovascular system: aortic dilation/aneurysm, aortic dissection, mitral valve prolapse
- Skeletal system: long arms and legs, tall and thin body type, scoliosis/kyphosis, pectus excavatum/pectus carinatum, long thin fingers, flexible joints, flat feet, crowded teeth
- Ocular system: severe nearsightedness, dislocated lens of the eye, detached retina, early glaucoma, early cataracts
- Other: stretch marks, spontaneous pneumothorax, dural ectasia
Rheumatoid Arthritis
- Classical deformities: boutonniere and swan neck
- Subcutaneous nodules on extensor surfaces (e.g., elbows)
- Anemia due to gastrointestinal bleeding from NSAID use
- Splenomegaly (Felty's syndrome)
- Lymphatic infiltration: salivary and lacrimal glands (Sjögren's syndrome)
- Lung involvement (related to disease or therapy)
- Fibrositis, amyloidosis
- Cardiovascular: pericarditis, valvulitis, fibrosis
- Ocular: keratoconjunctivitis sicca (dry eyes), episcleritis, scleromalacia
- Neurological: mononuritis multiplex, atlantoaxial subluxation
Osteoarthritis
- Use aspirin/corticosteroids with caution
- Hemorrhagic diatheses
- Artificial joints: AB prophylaxis
Gout
- Oral ulcerations
Ankylosing Spondylitis
- 10% TMJ involvement
Systemic Lupus Erythematosus (SLE)
- Autoimmune disease causing inflammation and tissue damage in various organs
- Affects joints, skin, brain, lungs, kidneys, and blood vessels
Dermatomyositis (DM)
- Long-term inflammatory disorder affecting skin and muscles
- Skin rash and muscle weakness, sudden onset or gradual development
Syphilis
- Acquired and Congenital: first, second, and third stages
- First Stage (Primary Syphilis): chancre, regional lymphadenopathy
- Second Stage (Secondary Syphilis): flu-like symptoms, generalized lymphadenopathy, skin lesions, mucous patches
- Third Stage (Tertiary Syphilis): neurosyphilis, cardiovascular syphilis, gummatous syphilis
HIV/AIDS
- Immunodeficiency: vulnerability to bacterial, viral, parasitic infections (e.g., Pneumocystis jirovecii pneumonia, Aspergillus, Candida, Coxsackie virus, cytomegalovirus, Mycobacterium, Toxoplasma)
- Kaposi sarcoma, lymphomas, leukemias, carcinomas
- Symptoms: fever, weight loss, weakness, fatigue, muscle/joint/head/throat pain, diarrhea, lymphadenopathy
Oral Manifestations of HIV
- KNUG (Necrotizing Ulcerative Gingivitis)
- Rapidly progressing periodontitis
- Delayed wound healing
- Rare oral infections (Kaposi sarcoma, SCC, Non-Hodgkin lymphoma, oral histoplasmosis, oral candidiasis, HSV, Herpes zoster, cytomegalovirus infection, hairy leukoplakia)
Epilepsy
- Tonic-clonic contractions, postictal confusion
- Bumpers to prevent tongue biting during a seizure
- Protect the airway from saliva
- Corneal reflex, Babinski reflex positive
Antiepileptics
- Carbamazepine (Tegretol): agranulocytosis
- Diphenylhydantoin (Epanutin): gingival hyperplasia
- Valproate: dental problems associated with convulsion, drug reactions, gingival hyperplasia, bleeding tendencies, psychiatric reactions
Multiple Sclerosis (MS)
- Demyelinated plaques (amyloid) in the central nervous system
- Affects various sites, neural conduction is depressed
- Medication: acute (ACTH), chronic (methylprednisolone)
- Dental signs: paresthesia, anesthesia, trigeminal neuralgia, trismus
Parkinson's Disease
- Decreased dopamine release
- Tremors, rigidity, bradykinesia
- Confusion, dementia
- Ataxic walking
- Hypersalivation
Myasthenia Gravis
- Acetylcholine inhibition causes neuromuscular blockage
- Thymoma
- Young females, males over 50
- Weakness, chewing and eye muscle weakness
- Dry mouth, increased caries
- Prohibited drugs: ester local anesthetics (procaine), tetracycline, clindamycin, lincomycin, aspirin
Cerebrovascular Disease (CVD)
- Sudden loss of neurological function
- Atherosclerosis in carotid and cerebral arteries
- Paralysis (hemiplegia, paraplegia, quadriplegia)
- Aspirin use
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Description
This quiz explores various genetic conditions such as Osteogenesis Imperfecta, Cleidocranial Dysostosis, Osteopetrosis, Marfan Syndrome, and Rheumatoid Arthritis. It highlights the implications these conditions have on dental health and treatment considerations. Test your knowledge on the interactions between genetics and oral health.
