General Study Notes Quiz
48 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What type of mutation results from a base being inserted or deleted in a DNA sequence, which subsequently alters the entire amino acid sequence?

  • Transversion Mutation
  • Point Mutation
  • Missense Mutation
  • Frameshift Mutation (correct)
  • Which repair mechanism do DNA glycosylases specifically participate in?

  • Homologous recombination
  • Single-strand break repair
  • Nucleotide excision repair
  • Base excision repair (correct)
  • What is the term for a mutation that does not change the resulting amino acid due to a codon alteration?

  • Silent mutation (correct)
  • Non-sense mutation
  • Frameshift mutation
  • Gene duplication
  • What is the post-replicative DNA repair pathway commonly known as?

    <p>Mis-match repair pathway</p> Signup and view all the answers

    Why does a mutation in the P53 gene increase cancer risk?

    <p>It prevents apoptosis from occurring.</p> Signup and view all the answers

    Which of the following statements about the P53 protein is true?

    <p>It activates P21 protein.</p> Signup and view all the answers

    What type of damage does UV radiation typically cause in DNA?

    <p>Dimers between adjacent pyrimidines</p> Signup and view all the answers

    What is the likely cause of Xeroderma pigmentosum based on its relation to DNA repair?

    <p>Impaired nucleotide excision repair</p> Signup and view all the answers

    What is the role of DNA gyrase during DNA replication?

    <p>To form breaks in DNA to relieve super-coiling</p> Signup and view all the answers

    Which enzyme is specifically responsible for initiating RNA synthesis at the replication site?

    <p>Primase</p> Signup and view all the answers

    How does DNA synthesis occur in terms of the direction of strand growth?

    <p>DNA is synthesized only in the 5' to 3' direction</p> Signup and view all the answers

    What structures, indicated by the letter E in a DNA replication diagram, are involved in the process?

    <p>Okazaki fragments</p> Signup and view all the answers

    What facilitates the movement of DNA molecules through agarose gel in electrophoresis?

    <p>The presence of negatively charged phosphates</p> Signup and view all the answers

    Which of the following accurately describes how eukaryotic chromosomes are replicated?

    <p>Bidirectionally from multiple origins of replication</p> Signup and view all the answers

    Which enzyme is mainly responsible for unwinding the DNA double helix during replication?

    <p>Helicase</p> Signup and view all the answers

    What is a key reason for the specific directionality (5' to 3') of DNA synthesis?

    <p>Because DNA polymerases can only add nucleotides to the 3' end of the strand</p> Signup and view all the answers

    What activates transcription in the lac operon when lactose is present?

    <p>Isomer of lactose binds to the repressor.</p> Signup and view all the answers

    Which statement about eukaryotic gene expression is correct?

    <p>Control of the rate in which genes are transcribed is essential.</p> Signup and view all the answers

    What is the correct sequence of structures in a typical mRNA molecule synthesized in a prokaryotic cell?

    <p>3' trailing sequences - Coding sequences - Termination signals - Leader sequences</p> Signup and view all the answers

    What role does the regulatory region play in a bacterial operon?

    <p>It generally occurs at the 5' end and upstream of the structural genes.</p> Signup and view all the answers

    What is a primary reason only one strand of DNA is used for transcription?

    <p>The template strand must be read in the 3' to 5' direction.</p> Signup and view all the answers

    Which statement is true regarding introns in human genes?

    <p>They can be alternatively spliced to form different proteins.</p> Signup and view all the answers

    What modification is made to the 3' end of eukaryotic pre-mRNA molecules?

    <p>Cutting and adding 100-250 adenine nucleotides.</p> Signup and view all the answers

    Which of the following is false regarding DNA transcription?

    <p>Only exons are transcribed into mRNA.</p> Signup and view all the answers

    Which of the following statements about the role of histone acetylases is accurate?

    <p>They promote DNA unwinding.</p> Signup and view all the answers

    If thymine constitutes 25% of the bases in a DNA sample, what is the percentage of guanine in that sample?

    <p>25%</p> Signup and view all the answers

    Which statement accurately describes the complement of the DNA strand 5'AGATCCG-3'?

    <p>3'-TCTAGGC-5'</p> Signup and view all the answers

    Which of the following sugars is specifically found in RNA?

    <p>D-Ribose</p> Signup and view all the answers

    Which of the following components is mismatched with its function in a gene?

    <p>Exons are non-coding sequences.</p> Signup and view all the answers

    What is the function of RNA polymerase during transcription?

    <p>It reads the template strand from 3' to 5' and synthesizes RNA in 5' to 3'.</p> Signup and view all the answers

    What abnormality is most likely linked to the shorter P53 protein in a 28-year-old man?

    <p>Point mutation that introduces a stop codon.</p> Signup and view all the answers

    Which statement regarding mitochondrial DNA is incorrect?

    <p>It exists only in eukaryotic organisms.</p> Signup and view all the answers

    What prevents the reformation of the double helix during DNA replication once the strands are separated?

    <p>Single-strand binding proteins</p> Signup and view all the answers

    At which end does each Okazaki fragment begin?

    <p>5' end with a separate RNA primer</p> Signup and view all the answers

    Which amino acid is virtually always found at the N-terminal of a newly-formed protein?

    <p>Methionine</p> Signup and view all the answers

    What does the anticodon 3'-GAU-5' correspond to?

    <p>5'-CUA-3'</p> Signup and view all the answers

    How does the first nucleotide at the 5' end of a new mRNA chain differ from other nucleotides in the chain?

    <p>It retains its triphosphate group</p> Signup and view all the answers

    What is the role of elongation factor EF-Tu in translation?

    <p>To deliver aminoacyl-tRNA to the 'A' site</p> Signup and view all the answers

    What does histone deacetylase do in relation to gene expression?

    <p>Suppresses gene expression by altering histone binding</p> Signup and view all the answers

    Which of the following statements about the lac operon is false?

    <p>It promotes gene expression when glucose levels are high</p> Signup and view all the answers

    Which dye is commonly used to visualize DNA on agarose gel under UV light?

    <p>Ethidium bromide</p> Signup and view all the answers

    What are the genetic strands called that result from the separation of sister chromatids?

    <p>Daughter chromosomes</p> Signup and view all the answers

    What group confers a negative charge to DNA molecules, aiding in agarose gel electrophoresis?

    <p>Phosphate groups</p> Signup and view all the answers

    During which phase of meiosis do bivalent chromosomes align?

    <p>Metaphase</p> Signup and view all the answers

    What key event in meiosis can lead to the formation of trisomies and monosomies?

    <p>Nondisjunction</p> Signup and view all the answers

    Which statement about nondisjunction is NOT accurate?

    <p>It separates sister chromatids.</p> Signup and view all the answers

    Which human disease is least likely to be linked with aneuploidy?

    <p>Fragile X syndrome</p> Signup and view all the answers

    What is the final concentration of a 1M MgCl2 stock solution needed to achieve 8mM in a 25ul PCR reaction?

    <p>0.20 ul</p> Signup and view all the answers

    Study Notes

    No specific text provided. Please provide the text you would like me to create study notes for.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    Test your knowledge with this quiz focused on creating effective study notes. Answer questions related to study techniques, organizing materials, and optimal note-taking strategies. Perfect for students looking to enhance their learning skills.

    More Like This

    Study Note Generation Quiz
    0 questions

    Study Note Generation Quiz

    FantasticAwareness9455 avatar
    FantasticAwareness9455
    Effective Study Notes Techniques
    5 questions
    General Study Notes
    64 questions

    General Study Notes

    SmilingObsidian1272 avatar
    SmilingObsidian1272
    General Notes on Note-Taking
    8 questions

    General Notes on Note-Taking

    ComprehensiveRainbowObsidian avatar
    ComprehensiveRainbowObsidian
    Use Quizgecko on...
    Browser
    Browser