General Information Quiz
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What is believed to have contributed to the zoonotic jump of smallpox?

  • Low population density
  • Isolation of communities
  • High-altitude habitation
  • Large populations and trade routes (correct)

Smallpox was effectively eradicated as a disease by the end of the 19th century.

False (B)

Which significant event in the 11th century contributed to the increased presence of smallpox in Europe?

The Crusades

Smallpox spread rapidly across the plains due in part to the __________ trade.

<p>slave</p> Signup and view all the answers

Match the following aspects to their respective characteristics of smallpox spread:

<p>Intentional spread = Biological warfare using infected items Zoonotic origin = Origin likely from gerbils or camels Endemic status = Seasonal and regional outbreaks in the old world Increased presence = Returning Crusaders in the 11th century</p> Signup and view all the answers

What was one of the primary benefits of transitioning from hunting and gathering to intensive farming during the Holocene?

<p>Increased food production (B)</p> Signup and view all the answers

Sedentary populations have lower risks of interpersonal violence compared to foraging societies.

<p>False (B)</p> Signup and view all the answers

What is a major nutritional deficiency associated with a diet primarily based on maize?

<p>Low iron absorption</p> Signup and view all the answers

The shift from diverse foraging diets to agriculture is often marked by a reliance on _____ as a primary food source.

<p>carbohydrates</p> Signup and view all the answers

Match each crop with its associated nutritional deficiency:

<p>Maize = Low iron absorption Millet = Iron deficiency Rice = Protein deficiency Wheat = Low bioavailability of vitamin A</p> Signup and view all the answers

Which of the following is a symptom of anemia?

<p>Porotic hyperostosis (A)</p> Signup and view all the answers

Dietary isotopes can provide insight into the types of food an individual is consuming.

<p>True (A)</p> Signup and view all the answers

What environmental factors contributed to the shift toward agriculture during the Holocene?

<p>Climate change and local resource availability</p> Signup and view all the answers

Which type of DNA correlates more with dentine as opposed to calculus?

<p>Soil environmental DNA (C)</p> Signup and view all the answers

Opportunistic pathogens can only cause infections in hosts.

<p>False (B)</p> Signup and view all the answers

What type of milk proteins have been found in Viking calculus?

<p>beta lactic globulin</p> Signup and view all the answers

Which of the following is NOT a resource or service provided by domesticated animals?

<p>Nutrition (C)</p> Signup and view all the answers

Domesticated animals generally have shorter lifespans compared to their wild counterparts.

<p>False (B)</p> Signup and view all the answers

The presence of __________ in calculus can provide insight into ancient diseases.

<p>opportunistic pathogens</p> Signup and view all the answers

Match the following findings with their significance:

<p>Eukaryotic DNA = Presence in calculus Bacterial proteins = Immune response Milk proteins = Dairying spread Virulence factors = Ancient bacteria comparison</p> Signup and view all the answers

What type of infectious disease is transmitted from non-human animals to humans?

<p>Zoonotic disease</p> Signup and view all the answers

What major components are primarily found in calculus?

<p>Bacterial and human proteins (C)</p> Signup and view all the answers

Animals used for _____ often show signs of care and veterinary assistance.

<p>domestication</p> Signup and view all the answers

Protein secretions observed in calculus are linked to the immune response against specific bacterial proteins.

<p>True (A)</p> Signup and view all the answers

Match the following domesticated animals with their respective domestication times:

<p>Dogs and wolves = 33,000 – 18,000 years ago Sheep and goats = 11,000 – 10,500 years ago Pigs, cows, and ox = 8,000 years ago Horses and donkeys = 5,500 years ago</p> Signup and view all the answers

Which of the following describes the genetic changes in domesticated animals?

<p>Changes in temperament and physical characteristics (D)</p> Signup and view all the answers

What kind of dietary components have been observed in calculus?

<p>Connective tissue and starch granules</p> Signup and view all the answers

Enzootic diseases are exclusively found in humans.

<p>False (B)</p> Signup and view all the answers

What is the primary purpose of animal domestication in human society?

<p>To provide resources and services such as protection, labor, and food.</p> Signup and view all the answers

What is a significant risk factor for tuberculosis (TB) exposure?

<p>Agglomeration (D)</p> Signup and view all the answers

Latent or dormant TB is symptomatic and contagious.

<p>False (B)</p> Signup and view all the answers

Name two symptoms of tuberculosis.

<p>Fever and weight loss</p> Signup and view all the answers

TB transmitted through ingestion can lead to __________ TB.

<p>gastro-intestinal</p> Signup and view all the answers

What was a major factor that led to an increase in TB cases after the agricultural revolution?

<p>Working with animals and products (C)</p> Signup and view all the answers

Match the type of TB to its description:

<p>Pulmonary TB = Respiratory transmission Gastrointestinal TB = Ingesting contaminated food Latent TB = Non-contagious but can reactivate Skeletal TB = Targets specific bones</p> Signup and view all the answers

The majority of individuals with TB show clear evidence of death directly caused by the disease.

<p>False (B)</p> Signup and view all the answers

What is Potts disease associated with?

<p>Tuberculosis of the spine</p> Signup and view all the answers

What disease was primarily associated with Edward Jenner's vaccination efforts in 1796?

<p>Smallpox (C)</p> Signup and view all the answers

Vaccination using cowpox was considered more risky than variolation with smallpox.

<p>False (B)</p> Signup and view all the answers

What is the primary pathogen that causes tuberculosis?

<p>Mycobacterium tuberculosis</p> Signup and view all the answers

The concept of sanitariums arose as a treatment for chronic infectious diseases, particularly _____ disease.

<p>tuberculosis</p> Signup and view all the answers

Which of the following diseases has been found in permafrost excavations?

<p>Smallpox (D)</p> Signup and view all the answers

Match the disease with its corresponding bacteria:

<p>Tuberculosis = Mycobacterium tuberculosis Leprosy = Mycobacterium leprae Anthrax = Bacillus anthracis Influenza = Influenza virus</p> Signup and view all the answers

Only upper classes were reported to have tuberculosis in society during historical times.

<p>False (B)</p> Signup and view all the answers

What is a common method of transmission for tuberculosis?

<p>Inhaling droplets from an infected individual</p> Signup and view all the answers

Flashcards

Agricultural Revolution

A shift from hunting, gathering, and foraging to intensive farming, leading to increased food production, storage, and population density. This transformation is marked by changes in social structure, property ownership, and task specialization.

Dietary Shift in Agriculture

The move to a more limited diet focused on specific crops like grains led to nutritional deficiencies, including poor dental health and a decline in dietary diversity.

Sedentary Lifestyle and Disease

Living in close proximity with domesticated animals and poor sanitation practices in early agricultural societies contributed to increased chances of disease transmission.

Dietary Isotopes and Ancient Diet

Stable isotopes in human remains provide insights into past diets, allowing researchers to analyze the chemical composition of food intake and understand changes in dietary patterns over time.

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Malnutrition in Agriculture

The reliance on specific grains in early agriculture led to nutritional deficiencies, particularly in protein, iron, and essential vitamins.

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Anemia and Porotic Hyperostosis

Porotic hyperostosis is a skeletal condition characterized by porous and expanded bones, often a symptom of anemia, which is a deficiency in red blood cells.

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Why Agriculture?

The exact reasons for the shift to agriculture remain partly unresolved but likely involve a combination of factors, including climate change, adaptations of plants and animals, and local resources and knowledge.

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Interpersonal Violence in Agriculture

The increased population density and competition for resources, arising from a sedentary lifestyle, likely contributed to higher rates of interpersonal violence in early agricultural societies.

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Domestication

The process of humans controlling and modifying an animal species for specific purposes, typically for resources or services. This includes managing their behavior, nutrition, reproduction, and movement.

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Benefits of Domestication

Domestication provides advantages for both humans and animals. Humans gain access to resources like food, labor, and protection, while animals benefit from healthcare, safety from predators, controlled population growth, and better nutrition.

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Domestication Process

Domestication occurs through a gradual, multi-step process starting with taming young animals and then managing groups, selectively breeding desirable traits, and integrating animals into society.

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Evidence of Domestication

Evidence of domestication is found in animal demographics, physical changes, genetic variations, disease patterns, and signs of human care, indicating distinct differences from wild populations.

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Osteoarthritis in Domestication

Domesticated animals often develop osteoarthritis at a younger age than their wild counterparts due to the increased physical stress imposed by humans.

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Simultaneous Domestication

Multiple animal species were domesticated during similar periods, suggesting a shared human need or opportunity.

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Zoonotic Disease

A disease that can be transmitted from animals to humans, potentially spreading back to animals or evolving into human-only strains.

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Vectors and Reservoirs

Animals can act as vectors (carriers) and reservoirs (sources) for various pathogens and parasites, playing a crucial role in disease transmission.

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Calculus Microbiome

The unique bacterial community found in dental calculus, distinct from dentine and carious dentine. Calculus harbors more bacteria from human oral studies while dentine shows correlation with soil and burial environmental DNA.

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Calculus Composition

Calculus contains a diverse mix of components beyond bacteria, including human and plant DNA, archaea, bacteriophage, and eukaryotic DNA. This reflects the complex interaction of the host, diet, and oral environment.

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Opportunistic Pathogens

Bacteria found in calculus that can cause infections under certain conditions, but often remain dormant and asymptomatic in the host.

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Dental Health Clues

Calculus can reveal major periodontal pathogens, indicating past dental health issues such as inflammation, alveolar resorption, and periodontal osteoporosis.

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Virulence Factor Analysis

Studying ancient DNA in calculus allows researchers to compare ancient bacterial strains with modern ones, revealing virulence factors acquired through evolution.

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Host Immune Response

The presence of human secretory proteins in calculus indicates the host's immune response to bacterial presence. These proteins, especially from neutrophils, are linked to the innate immune system.

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Dietary Analysis

Calculus can be analyzed for food-derived components like connective tissue, plant photolytes, starch granules, and milk proteins, providing insights into ancient diets.

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Dairy Spread

The presence of milk proteins like beta-lactic globulin in calculus helps track the spread of dairying through time and geographic regions.

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Smallpox Origin

Smallpox likely originated in Egypt or the Near East, spreading to Europe and the Americas. The zoonotic jump event, though not confirmed, is potentially linked to gerbilles or camels.

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First Smallpox Pandemic

The Roman Empire experienced the first major smallpox pandemic, known as the Antonine Plague. This led to smallpox becoming endemic in the Old World, causing seasonal and regional outbreaks.

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Smallpox in the Americas

Smallpox reached the Americas with early European settlements and trade routes. It spread rapidly, causing major outbreaks. There is evidence that smallpox was intentionally spread during the European colonization of the Americas.

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Smallpox and the Slave Trade

The European slave trade to the Americas contributed to the spread of smallpox. The enslaved people, with weakened immune systems, were more susceptible to infection and disease transmission.

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Bioarcheological Evidence

Bioarchaeology utilizes skeletal remains to explore the history of smallpox. However, osteological changes in individuals who contracted smallpox are limited.

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What is Latent TB?

Latent TB is a state where the bacteria is encapsulated in the body, preventing infection spread. It is not contagious or symptomatic and does not cause illness but can reactivate in a weakened immune system.

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How does TB spread?

Tuberculosis primarily spreads through the air when a person with active TB coughs, sneezes, speaks, or sings. It can also be ingested through contaminated food or milk.

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What are the symptoms of active TB?

Active TB symptoms include prolonged cough, chest pain, fatigue, weight loss, night sweats, fever, chills, appetite loss, and coughing up blood.

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What are the risk factors for TB?

Risk factors include overcrowding, poor ventilation, lack of sunlight, malnutrition, and vitamin D deficiency. Individuals working with animals or consuming unpasteurized milk are also at higher risk.

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What is Pott's Disease?

Pott's Disease is a type of skeletal TB that affects the spine. It involves the breakdown of vertebrae from lytic lesions that cause kyphosis, a curvature of the spine.

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Why is skeletal TB important for understanding past populations?

Skeletal TB can leave visible changes on bones, providing evidence of infection in archaeological remains. It offers insights into past health and disease patterns, despite limited information on the prevalence of TB in general.

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What skeletal structures does TB primarily target?

TB primarily targets oxygenated areas of the body, including spongy bone, intervertebral discs, and the growth plates of long bones. It leads to lytic lesions (bone destruction).

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What is the role of Vitamin D in TB?

Vitamin D plays a critical role in immune function and bone health. Vitamin D deficiency increases the risk of TB infection and susceptibility to the disease.

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Variolation with Cowpox

A safer alternative to smallpox inoculation using cowpox, a related virus that causes a milder disease. It still exposed the body to the same genus but with reduced risks.

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Zombie Viruses

Viruses recovered from ancient remains, such as permafrost, capable of being reanimated. These resurrected viruses pose a potential threat as they can potentially infect humans and spread diseases.

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How did the concept of TB affect society?

Tuberculosis was viewed differently by social classes. The lower classes saw it as a common disease, while the upper classes romanticized it, linking it to the Virgin Mary. This difference in perception affected treatment and disclosure practices.

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Sanitarium Treatment

A specialized care facility for chronic infectious diseases like tuberculosis. These institutions played a key role in the development of understanding and treating tuberculosis.

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Mycobacterial Infections

A group of bacterial infections caused by Mycobacterium species, including tuberculosis and leprosy. These infections are often chronic and can be difficult to treat.

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Leprosy

A chronic infectious disease caused by Mycobacterium leprae and Mycobacterium lepromatosis. It is characterized by skin lesions and nerve damage and can be contracted from infected humans or their animal reservoirs.

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Tuberculosis (Mycobacterium tuberculosis complex)

A highly contagious bacterial infection caused by Mycobacterium tuberculosis. It primarily affects the lungs but can spread to other organs. Transmission occurs through inhaling droplets expelled by infected individuals.

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Animal Reservoir for Tuberculosis

Animals like cattle, camelids, seals, deer, and other primates can harbor Mycobacterium tuberculosis strains specific to their species. These strains can be transmitted to humans, making those animals potential reservoirs.

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