Podcast
Questions and Answers
What is the main goal of gene therapy?
What is the main goal of gene therapy?
- To treat loss-of-function genetic disorders by delivering therapeutic DNA sequences into the nucleus of a cell (correct)
- To introduce genes into somatic cells for ethical considerations
- To alter the genetic makeup of germ cells
- To amplify and isolate normal genes
What is the difference between germ-line gene therapy and somatic gene therapy?
What is the difference between germ-line gene therapy and somatic gene therapy?
- Germ-line gene therapy introduces genes into somatic cells, while somatic gene therapy introduces therapeutic genes into germ-cells
- Germ-line gene therapy is used for ethical considerations, while somatic gene therapy is used to alter genetic makeup
- Germ-line gene therapy corrects severe disorders, while somatic gene therapy aims to treat loss-of-function genetic disorders
- Germ-line gene therapy introduces therapeutic genes into germ-cells or specific embryonal cells, while somatic gene therapy introduces genes into somatic cells (correct)
What happens after germ-line gene therapy is performed?
What happens after germ-line gene therapy is performed?
- The therapeutic gene will only be carried by the offspring
- The therapeutic gene will not be passed on to the offspring
- The therapeutic gene will only be carried by the individual
- All cells of the individual derived from these cells will carry the therapeutic gene, including his or her germ cells (correct)
What are the principles of gene therapy?
What are the principles of gene therapy?
What is the main problem with gene therapy in terms of the longevity of treatment?
What is the main problem with gene therapy in terms of the longevity of treatment?
What was the first disease targeted for gene therapy?
What was the first disease targeted for gene therapy?
What is Gendicine designed to treat?
What is Gendicine designed to treat?
What is the main limitation of direct injection as a gene therapy delivery method?
What is the main limitation of direct injection as a gene therapy delivery method?
Which gene therapy approach involves the use of the Herpes simplex virus Thymidine kinase (HSV-tk) gene?
Which gene therapy approach involves the use of the Herpes simplex virus Thymidine kinase (HSV-tk) gene?
What is the main gene therapy approach for treating Cystic Fibrosis?
What is the main gene therapy approach for treating Cystic Fibrosis?
What is the gene therapy approach for treating Duchenne Muscular Dystrophy (DMD)?
What is the gene therapy approach for treating Duchenne Muscular Dystrophy (DMD)?
What is the main challenge in gene therapy for multigene disorders?
What is the main challenge in gene therapy for multigene disorders?
Which gene therapy delivery method involves the use of repeated injections and a large number of DNA?
Which gene therapy delivery method involves the use of repeated injections and a large number of DNA?
What is the main challenge associated with in vivo gene therapy for Cystic Fibrosis?
What is the main challenge associated with in vivo gene therapy for Cystic Fibrosis?
What is the main challenge associated with naked plasmid DNA gene therapy for Duchenne Muscular Dystrophy (DMD)?
What is the main challenge associated with naked plasmid DNA gene therapy for Duchenne Muscular Dystrophy (DMD)?
What is the main challenge associated with suicide gene therapy?
What is the main challenge associated with suicide gene therapy?
