Podcast
Questions and Answers
Which of the following is a characteristic of the sickle cell anemia mutation?
Which of the following is a characteristic of the sickle cell anemia mutation?
- Replacement of glutamic acid with valine (correct)
- Replacement of valine with glutamic acid
- Replacement of alanine with glycine
- Replacement of glycine with alanine
What is the function of hydroxyurea treatment in sickle cell patients?
What is the function of hydroxyurea treatment in sickle cell patients?
- Increases fetal globin gene expression (correct)
- Increases adult globin gene expression
- Decreases fetal globin gene expression
- Decreases adult globin gene expression
What is the rationale behind placing the African American patient on hydroxyurea?
What is the rationale behind placing the African American patient on hydroxyurea?
- To increase blood oxygen levels
- To reduce vasoocclusive episodes (correct)
- To increase vasoocclusive episodes
- To reduce blood oxygen levels
Which DNA-binding motif is found in the Myogenic transcription factor MyoD?
Which DNA-binding motif is found in the Myogenic transcription factor MyoD?
Which gene regulatory protein controls the lysogenic state of Lambda phage?
Which gene regulatory protein controls the lysogenic state of Lambda phage?
Which region of DNA acts as a barrier to spread heterochromatin to the neighboring region?
Which region of DNA acts as a barrier to spread heterochromatin to the neighboring region?
Which of the following is NOT a way by which gene regulatory proteins can be activated?
Which of the following is NOT a way by which gene regulatory proteins can be activated?
Which part of the DNA helix do most gene regulatory proteins bind to?
Which part of the DNA helix do most gene regulatory proteins bind to?
Which DNA binding motif is characterized by amino acid side chains in gene regulatory proteins making hydrogen bonds with bases from outside?
Which DNA binding motif is characterized by amino acid side chains in gene regulatory proteins making hydrogen bonds with bases from outside?
Which DNA binding motif forms heterodimers, expanding the repertoire of DNA-binding specificities?
Which DNA binding motif forms heterodimers, expanding the repertoire of DNA-binding specificities?
Which DNA binding motif is characterized by two monomers held together in a four-helix bundle?
Which DNA binding motif is characterized by two monomers held together in a four-helix bundle?
Which class of gene regulatory proteins plays a critical part in orchestrating fly development?
Which class of gene regulatory proteins plays a critical part in orchestrating fly development?
Which type of protein binds to a specific region of DNA to prevent transcription of an adjacent gene?
Which type of protein binds to a specific region of DNA to prevent transcription of an adjacent gene?
What is the function of an activator protein?
What is the function of an activator protein?
What is an enhancer element?
What is an enhancer element?
What is the function of a TATA box?
What is the function of a TATA box?
What are general transcription factors?
What are general transcription factors?
What allows gene regulatory proteins to work from a distance?
What allows gene regulatory proteins to work from a distance?
Which of the following is a function of hydroxyurea in preventing vaso-occlusive episodes?
Which of the following is a function of hydroxyurea in preventing vaso-occlusive episodes?
What is the role of XIST RNA in X-chromosome inactivation?
What is the role of XIST RNA in X-chromosome inactivation?
Which of the following is a characteristic of CpG islands?
Which of the following is a characteristic of CpG islands?
What is the effect of DNA hypermethylation on gene expression in cancer cells?
What is the effect of DNA hypermethylation on gene expression in cancer cells?
How is DNA methylation pattern inherited during cell division?
How is DNA methylation pattern inherited during cell division?
What happens to CpG islands during the course of evolution?
What happens to CpG islands during the course of evolution?
Which of the following best describes why cells in different tissues of a multicellular organism produce different types of proteins?
Which of the following best describes why cells in different tissues of a multicellular organism produce different types of proteins?
What is the function of a promoter in gene expression?
What is the function of a promoter in gene expression?
What is positive control in gene expression?
What is positive control in gene expression?
What is negative control in gene expression?
What is negative control in gene expression?
Which of the following statements is true about the genetic information in a differentiated cell?
Which of the following statements is true about the genetic information in a differentiated cell?
What is the evidence that a skin cell nucleus contains all the genetic information needed to make different cell types?
What is the evidence that a skin cell nucleus contains all the genetic information needed to make different cell types?
