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Questions and Answers
What are the potential consequences of modified gene expression in the context of the provided content?
What are the potential consequences of modified gene expression in the context of the provided content?
- Enhanced DNA replication fidelity, reducing the risk of mutations.
- Reduced chromatin accessibility, leading to a decrease in gene expression.
- Disrupted gene regulation, potentially leading to aberrant cell growth and function. (correct)
- Increased histone production, leading to a more stable and robust nuclear structure.
Which of the following is NOT a consequence of modified gene expression described in the content?
Which of the following is NOT a consequence of modified gene expression described in the content?
- Breakdown of nuclear lamina
- Loss of histones
- Increased DNA methylation (correct)
- Chromatin remodelling
The content suggests that modified gene expression can lead to alterations in heterochromatin. What is heterochromatin, and what is its role in the cell?
The content suggests that modified gene expression can lead to alterations in heterochromatin. What is heterochromatin, and what is its role in the cell?
- Heterochromatin is a region of tightly packed DNA, often associated with gene silencing. (correct)
- Heterochromatin refers to a specific type of histone modification that attracts DNA methyltransferases.
- Heterochromatin is a specialized region of the nucleus that regulates the movement of proteins between the cytoplasm and the nucleus.
- Heterochromatin is a region of highly condensed DNA, responsible for transcription of ribosomal RNA.
Which cellular structure is directly affected by the breakdown of the nuclear lamina, as described in the content?
Which cellular structure is directly affected by the breakdown of the nuclear lamina, as described in the content?
What is the main implication of altered gene expression and its connected consequences as described in the content?
What is the main implication of altered gene expression and its connected consequences as described in the content?
Flashcards
Modified Gene Expression
Modified Gene Expression
Changes in how genes are activated or silenced.
Loss of Histones
Loss of Histones
Reduction of proteins that package and order DNA into structural units.
Heterochromatin Expansion
Heterochromatin Expansion
Increase in tightly packed chromatin, often leading to gene silencing.
Transcriptional Changes
Transcriptional Changes
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Nuclear Lamina Breakdown
Nuclear Lamina Breakdown
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Study Notes
Gene Expression Modifications
- Modified gene expression leads to a loss of histones.
- This results in an imbalance of repressive and activating histone modifications.
- There is an evasion and expansion of heterochromatin.
- Transcriptional changes occur as a consequence.
- The nuclear lamina breaks down, alongside chromatin remodeling.
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