Gel Properties and Characteristics
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Questions and Answers

What is the typical percentage of finely dispersed solids in pastes?

  • Up to 20%
  • Up to 50% (correct)
  • Up to 90%
  • Up to 70%
  • What is the primary function of pastes in dermatological applications?

  • To provide occlusion
  • To serve as a protective coating (correct)
  • To treat skin neoplasms
  • To absorb secretions
  • What type of paste is Triamcinolone acetonide dental paste?

  • Aqueous paste (correct)
  • Fatty paste
  • Aqueous gel
  • Hydrocarbon base
  • What is the purpose of adding antioxidants to pastes?

    <p>To improve stability</p> Signup and view all the answers

    What is the role of preservatives in pastes?

    <p>To prevent microbial growth</p> Signup and view all the answers

    Which of the following is a commonly used excipient in pastes?

    <p>Polydimethylsiloxane</p> Signup and view all the answers

    What is the purpose of using a hydrocarbon base in pastes?

    <p>To provide a soft, glossy base</p> Signup and view all the answers

    What is the fusion method used for in paste preparation?

    <p>To melt the base</p> Signup and view all the answers

    What is the function of Carbopol 980 in a pharmaceutical formulation?

    <p>Gelling agent</p> Signup and view all the answers

    What is the purpose of EDTA in a pharmaceutical formulation?

    <p>Stabilizer</p> Signup and view all the answers

    What is the primary function of Poloxamer 124 in a pharmaceutical formulation?

    <p>Surfactant</p> Signup and view all the answers

    What is the main characteristic of hydrogels?

    <p>Water-swollen structures composed of mainly hydrophilic polymers</p> Signup and view all the answers

    What is the process by which a gel takes up water (or solvent) and increases in volume?

    <p>Swelling or Imbibition</p> Signup and view all the answers

    What is the opposite of swelling or imbibition in gels?

    <p>Syneresis</p> Signup and view all the answers

    What is an example of a low-molecular-weight gelator (LMWG)?

    <p>Lecithin</p> Signup and view all the answers

    What is thixotropy in the context of gels?

    <p>The property of some gels that turn into a sol on shaking and reset to the gel on standing</p> Signup and view all the answers

    What is the primary function of Carbopol 980 in Adapalene gel?

    <p>Gelling agent</p> Signup and view all the answers

    What is the role of EDTA sodium in Adapalene gel?

    <p>Chelating agent/Stabilizer</p> Signup and view all the answers

    Which excipient is responsible for controlling the pH of Adapalene gel?

    <p>Sodium hydroxide</p> Signup and view all the answers

    What is the primary function of Propylene glycol in Adapalene gel?

    <p>Cosolvent</p> Signup and view all the answers

    Which excipient is responsible for preventing microbial growth in Adapalene gel?

    <p>Methylparaben</p> Signup and view all the answers

    What is the role of Poloxamer 124 in Adapalene gel?

    <p>Surfactant</p> Signup and view all the answers

    Which excipient is responsible for helping to create a consistent gel texture in Adapalene gel?

    <p>Carbopol 980</p> Signup and view all the answers

    What is the primary function of Purified water in Adapalene gel?

    <p>Solvent</p> Signup and view all the answers

    What is a characteristic of bentonite or kaolin-based gels?

    <p>Formation of a lamellar structure</p> Signup and view all the answers

    What is a common application of xerogels?

    <p>Film formation</p> Signup and view all the answers

    What is a factor to consider when choosing a topical preparation?

    <p>The type of lesion</p> Signup and view all the answers

    What is a potential effect of an occlusive vehicle on the active ingredient?

    <p>Enhanced penetration</p> Signup and view all the answers

    What is a type of stimulus that can cause a drastic change in the properties of smart hydrogels?

    <p>All of the above</p> Signup and view all the answers

    What is a common characteristic of xerogels?

    <p>High porosity and high surface area</p> Signup and view all the answers

    Why is it important to clean the affected area before applying a topical agent?

    <p>To remove dirt and debris</p> Signup and view all the answers

    What is a patient counseling point for topical agents?

    <p>Wash hands before and after use</p> Signup and view all the answers

    What is the primary function of Carbopol 980 in Adapalene gel?

    <p>Gelling agent</p> Signup and view all the answers

    Which type of gel is Adapalene gel classified as?

    <p>Hydrogel</p> Signup and view all the answers

    What is the function of EDTA in Adapalene gel?

    <p>Stabilization</p> Signup and view all the answers

    What is the primary function of Methylparaben in Adapalene gel?

    <p>Preservation</p> Signup and view all the answers

    What is the purpose of Poloxamer 124 in Adapalene gel?

    <p>Solubilization</p> Signup and view all the answers

    What type of flow behavior is exhibited by inorganic gels?

    <p>Pseudoplastic flow</p> Signup and view all the answers

    What is the function of Propylene glycol in Adapalene gel?

    <p>Solvent</p> Signup and view all the answers

    What is the purpose of Sodium hydroxide and Hydrochloric acid in Adapalene gel?

    <p>pH adjustment</p> Signup and view all the answers

    What is the primary function of Carbopol 980 in Adapalene gel?

    <p>Gelling agent</p> Signup and view all the answers

    Which excipient is responsible for preventing microbial growth in Adapalene gel?

    <p>Methylparaben</p> Signup and view all the answers

    What is the primary function of EDTA sodium in Adapalene gel?

    <p>Chelating agent/Stabilizer</p> Signup and view all the answers

    What is the primary function of Poloxamer 124 in Adapalene gel?

    <p>Surfactant</p> Signup and view all the answers

    What is the primary function of Sodium hydroxide and Hydrochloric acid in Adapalene gel?

    <p>pH adjusters</p> Signup and view all the answers

    What is the primary function of Propylene glycol in Adapalene gel?

    <p>Cosolvent</p> Signup and view all the answers

    What is the primary function of Purified water in Adapalene gel?

    <p>Solvent</p> Signup and view all the answers

    What is the role of Carbopol 980, EDTA sodium, and Poloxamer 124 in Adapalene gel?

    <p>Gelling agent, Chelating agent/Stabilizer, and Surfactant</p> Signup and view all the answers

    What is the primary function of gelling agents in a pharmaceutical formulation?

    <p>To create a three-dimensional network and restrict the movement of particles</p> Signup and view all the answers

    Which of the following excipients is a chelating agent?

    <p>EDTA sodium</p> Signup and view all the answers

    What is the primary function of surfactants in a pharmaceutical formulation?

    <p>To reduce the surface tension of the formulation and improve its spreadability</p> Signup and view all the answers

    What is the primary function of preservatives in a pharmaceutical formulation?

    <p>To prevent microbial growth in the formulation</p> Signup and view all the answers

    What is the function of Carbopol 980 in Adapalene gel?

    <p>To create a three-dimensional network and restrict the movement of particles</p> Signup and view all the answers

    Which of the following excipients is a preservative?

    <p>Methylparaben</p> Signup and view all the answers

    What is the primary function of Poloxamer 124 in Adapalene gel?

    <p>To reduce the surface tension of the formulation and improve its spreadability</p> Signup and view all the answers

    What is the function of EDTA in Adapalene gel?

    <p>To chelate metal ions and prevent the degradation of active ingredients</p> Signup and view all the answers

    What is the primary function of a hydrocarbon base in pastes?

    <p>To provide a protective coating and absorb secretions from oozing lesions</p> Signup and view all the answers

    Which of the following is not a type of base used in pastes?

    <p>Liposome base</p> Signup and view all the answers

    What is the role of antioxidants in pastes?

    <p>To prevent oxidation and spoilage of the paste</p> Signup and view all the answers

    What is the purpose of adding preservatives to pastes?

    <p>To prevent microbial growth and spoilage of the paste</p> Signup and view all the answers

    What is the role of emulsifying ointment in pastes?

    <p>To facilitate the mixing of hydrophobic and hydrophilic ingredients</p> Signup and view all the answers

    What is the primary function of polydimethylsiloxane (liquid silicone) in pastes?

    <p>To act as an additional hydrophobic solvent</p> Signup and view all the answers

    Which of the following is a commonly used excipient in pastes?

    <p>All of the above</p> Signup and view all the answers

    What is the function of petrolatum in zinc oxide paste?

    <p>To act as an additional hydrophobic solvent</p> Signup and view all the answers

    What is the primary function of a chelating agent in a pharmaceutical formulation?

    <p>To prevent the degradation of the active ingredient by metal ions</p> Signup and view all the answers

    What is the primary function of a surfactant in a pharmaceutical formulation?

    <p>To reduce the surface tension of the formulation</p> Signup and view all the answers

    What is the primary function of a gelling agent in a pharmaceutical formulation?

    <p>To create a consistent gel texture</p> Signup and view all the answers

    What is the primary function of a preservative in a pharmaceutical formulation?

    <p>To prevent the growth of microorganisms</p> Signup and view all the answers

    What is the primary function of a cosolvent in a pharmaceutical formulation?

    <p>To enhance the solubility of the active ingredient</p> Signup and view all the answers

    What is the primary function of a solvent in a pharmaceutical formulation?

    <p>To dissolve the active ingredient</p> Signup and view all the answers

    What is the primary function of inorganic particles like bentonite or kaolin in gels?

    <p>To create a lamellar structure that can be extensively hydrated</p> Signup and view all the answers

    What is the primary function of a pH adjuster in a pharmaceutical formulation?

    <p>To adjust the pH of the formulation</p> Signup and view all the answers

    What is the effect of an occlusive vehicle on the active ingredient?

    <p>It enhances the penetration of the active ingredient</p> Signup and view all the answers

    What is the primary function of a gelling agent in hydrogels?

    <p>To create a cross-linked polymer network</p> Signup and view all the answers

    What is the characteristic of xerogels that makes them useful?

    <p>High surface area and porosity</p> Signup and view all the answers

    What type of stimulus can cause a drastic change in the properties of smart hydrogels?

    <p>All of the above</p> Signup and view all the answers

    What is the role of a chelating agent in a pharmaceutical formulation?

    <p>To remove metal ions that can affect the stability of the formulation</p> Signup and view all the answers

    What is the primary function of a surfactant in a pharmaceutical formulation?

    <p>To enhance the solubility of the active ingredient</p> Signup and view all the answers

    What is an important factor to consider when choosing a topical preparation?

    <p>The type of vehicle used</p> Signup and view all the answers

    Why is it important to clean and dry the affected area before applying a topical agent?

    <p>To remove dirt and debris that may affect the absorption of the topical agent</p> Signup and view all the answers

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