Podcast
Questions and Answers
Match each term to its definition
Match each term to its definition
sedative (anxiolytic) = reduces anxiety and exerts calming effect, CNS depression should be minimum hypnotics = induce sleep, CNS effects are more pronounced and follow a dose response Sedation/anxiolytic: = reduce nervous excitment, to calm anesthesia = without sensation
Which of the following is a prodrug benzodiazepine that is converted in the stomach by acid hydrolysis to an active drug?
Which of the following is a prodrug benzodiazepine that is converted in the stomach by acid hydrolysis to an active drug?
- Clorazepate (correct)
- Diazepam
- Alprazolam
- Lorazepam
What is clorazepate converted to once activated?
What is clorazepate converted to once activated?
- oxazepam
- diazepam
- desmethyldiazepam (correct)
- lorazepam
All sedative hypnotics cross the placental barrier and can sedate the baby.
All sedative hypnotics cross the placental barrier and can sedate the baby.
Match each drug to its class:
Match each drug to its class:
Match each class of drugs to its description:
Match each class of drugs to its description:
Match each drug to its description
Match each drug to its description
What is the half-life of phenobarbital?
What is the half-life of phenobarbital?
Dose adjustment for reduced kidney function is usually required for sedatives.
Dose adjustment for reduced kidney function is usually required for sedatives.
How is phenobarbital excretion increased?
How is phenobarbital excretion increased?
What percentage of phenobarbital is excreted unchanged in urine?
What percentage of phenobarbital is excreted unchanged in urine?
What can phenobarbital cause?
What can phenobarbital cause?
Benzodiazepines and the newer hypnotics do not change hepatic enzymes.
Benzodiazepines and the newer hypnotics do not change hepatic enzymes.
Which of the following binds to a GABA A receptor site different from the rest?
Which of the following binds to a GABA A receptor site different from the rest?
What kind of receptor is the GABA A receptor?
What kind of receptor is the GABA A receptor?
Match each drug group to its binding site:
Match each drug group to its binding site:
What is the mechanism of action (MOA) of benzodiazepines?
What is the mechanism of action (MOA) of benzodiazepines?
What is the mechanism of action (MOA) of barbiturates?
What is the mechanism of action (MOA) of barbiturates?
What can Benzodiazepines induce? (Select all that apply)
What can Benzodiazepines induce? (Select all that apply)
Barbiturates are more dangerous than benzodiazepines.
Barbiturates are more dangerous than benzodiazepines.
What are zolpidem, zaleplon, and eszopiclone used as?
What are zolpidem, zaleplon, and eszopiclone used as?
Match each benzodiazepine binding site ligand to its role:
Match each benzodiazepine binding site ligand to its role:
What is flumazenil used for?
What is flumazenil used for?
Why does flumazenil not reverse or block barbiturates, ethanol, or meprobamate?
Why does flumazenil not reverse or block barbiturates, ethanol, or meprobamate?
Match each drug to its use:
Match each drug to its use:
Match each to its description
Match each to its description
What is the usual cause of death due to overdose?
What is the usual cause of death due to overdose?
Benzodiazepines do not cause physiological dependence.
Benzodiazepines do not cause physiological dependence.
What is the benzodiazepine of choice for treating anxiety?
What is the benzodiazepine of choice for treating anxiety?
Which of the following are adverse drug reactions (ADRs) of sedative hypnotics? (Select all that apply)
Which of the following are adverse drug reactions (ADRs) of sedative hypnotics? (Select all that apply)
Where are orexin A and B found?
Where are orexin A and B found?
Which of the following is an orexin antagonist?
Which of the following is an orexin antagonist?
Which of the following was the world's first benzodiazepine drug?
Which of the following was the world's first benzodiazepine drug?
All barbiturates bind to GABA A receptors.
All barbiturates bind to GABA A receptors.
Match each drug to its use
Match each drug to its use
Which of the following benzodiazepines are considered safer for geriatric patients because their active metabolites are not retained? (Select all that apply)
Which of the following benzodiazepines are considered safer for geriatric patients because their active metabolites are not retained? (Select all that apply)
Flashcards
Capital of France (example flashcard)
Capital of France (example flashcard)
Paris
