COPY: Gastrointestinal Tests Overview

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Questions and Answers

What is considered a normal level of the non-invasive marker in stool for pancreatic function?

  • 100 - 200 µg/g stool
  • Under 100 µg/g stool
  • Below 75 mM concentration
  • 200 µg/g stool or higher (correct)

The secretin/CCK test requires the patient to consume food before the procedure.

False (B)

What is the minimum bicarbonate concentration that healthy subjects typically exhibit during the secretin/CCK test?

75 mM

A level of the non-invasive marker below _____ in feces indicates exocrine pancreatic insufficiency.

<p>200 µg/g</p> Signup and view all the answers

Match the following tests or methods with their characteristics:

<p>ELISA = Non-invasive marker for pancreatic function Secretin/CCK test = Invasive test requiring collection of pancreatic secretions Endoscopic ultrasonography = Imaging method with fine needle aspiration capability Trypsin and amylase tests = Comparison of enzyme activities to local standards</p> Signup and view all the answers

What is a common reason for measuring fasting plasma gastrin levels?

<p>Gastrinoma (B)</p> Signup and view all the answers

Serum amylase levels are significantly elevated in cases of chronic pancreatitis.

<p>False (B)</p> Signup and view all the answers

What bacterium is commonly associated with peptic ulcer disease?

<p>Helicobacter pylori</p> Signup and view all the answers

The Urease (CLO) test has a sensitivity of ________ for detecting Helicobacter pylori.

<p>90-95%</p> Signup and view all the answers

Match the following terms with their correct descriptions:

<p>Fasting plasma gastrin = Measured for gastrinoma assessment Serum amylase = Indicates acute pancreatitis when elevated Pancreatic elastase 1 = Non-invasive test for pancreatic function ELISA = Detects stool antigens for H. pylori</p> Signup and view all the answers

Which procedure has a sensitivity of 98% for diagnosing conditions related to peptic ulcer disease?

<p>Histology following biopsy (B)</p> Signup and view all the answers

A false positive can occur with serology testing for H. pylori.

<p>True (A)</p> Signup and view all the answers

What are two common causes of acute pancreatitis?

<p>Excessive alcohol and gallstones</p> Signup and view all the answers

Which of the following symptoms is commonly associated with Coeliac disease?

<p>Diarrhoea (D)</p> Signup and view all the answers

IgA deficiency occurs in 1 in 200 patients with Coeliac disease.

<p>False (B)</p> Signup and view all the answers

What type of antibodies should be measured to confirm Coeliac disease if a patient is IgA deficient?

<p>IgG antibodies to tissue transglutaminase</p> Signup and view all the answers

Patients with lactase deficiency often experience abdominal cramps and ______.

<p>diarrhoea</p> Signup and view all the answers

Match the following malabsorption tests with their related conditions:

<p>14C-triolein test = Fat malabsorption Blood glucose response after lactose = Lactase deficiency Antibody tests = Coeliac disease Serum ferritin measurements = Iron deficiency</p> Signup and view all the answers

In the 14C-triolein test, what is administered to the patient to evaluate fat malabsorption?

<p>14C-triolein in a fat meal (D)</p> Signup and view all the answers

Cholestatic liver disease may cause a positive fat malabsorption test due to the absence of bile salts.

<p>True (A)</p> Signup and view all the answers

What should be measured to assess mean cell characteristics in malabsorption syndromes?

<p>Mean red cell volume and mean corpuscular hemoglobin</p> Signup and view all the answers

What is the primary cause of bile salt malabsorption?

<p>Ileum damage (B)</p> Signup and view all the answers

The Faecal osmotic gap is calculated using the formula: 290 – 2 x ([faecal sodium] + [faecal potassium]).

<p>True (A)</p> Signup and view all the answers

Name one test used to detect bacterial overgrowth.

<p>Breath H2 test</p> Signup and view all the answers

Bile salts are normally absorbed in the __________.

<p>ileum</p> Signup and view all the answers

Match the following malabsorptive disorders with their corresponding symptoms:

<p>Coeliac disease = Gluten intolerance Lactase deficiency = Lactose intolerance Fat malabsorption = Steatorrhea Bile salt malabsorption = Diarrhea</p> Signup and view all the answers

Which of the following is a common symptom of fat malabsorption?

<p>Steatorrhea (D)</p> Signup and view all the answers

A serum 7 a-hydroxycholestenone test is invasive and requires a biopsy.

<p>False (B)</p> Signup and view all the answers

The condition characterized by inadequate absorption of nutrients is known as __________.

<p>malabsorption</p> Signup and view all the answers

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