6 Questions
Which hormone was the first gastrointestinal hormone to be discovered?
Secretin
What mainly stimulates the release of gastric inhibitory peptide?
Fatty acids and amino acids
Which hormone is secreted by the 'S' cells in the duodenum?
Secretin
What is the primary function of motilin?
Increasing gastrointestinal motility
Which hormone is released in response to acidic gastric juice emptying into the duodenum?
Secretin
How often are inter digestive myoelectric complexes stimulated by motilin?
Every 90 minutes
Study Notes
Gastrointestinal Hormones
Secretin
- Discovered as the first gastrointestinal hormone
- Produced by "S" cells in the duodenum's mucosa
- Released in response to acidic gastric juice entering the duodenum
- Has a mild effect on the motility of the GI tract
- Stimulates pancreatic secretion of bicarbonate to neutralize acid in the small intestine
Gastric Inhibitory Peptide (GIP)
- Secreted by the upper small intestine's mucosa
- Mainly responds to fatty acids and amino acids
- Also responds to carbohydrates, but to a lesser extent
- Decreases motor activity in the stomach
- Slows the emptying of gastric contents into the duodenum to prevent overloading the small intestine with food
Motilin
- Released by the upper duodenum during fasting
- Only function is to increase GI motility
- Released cyclically, stimulating waves of motility
- Involved in inter digestive myoelectric complexes that move through the stomach and small intestine every 90 minutes
- Inhibited after ingestion, but the mechanisms are unknown
Learn about the functions and characteristics of gastrointestinal hormones, including Secretin and Gastric Inhibitory Peptide (GIP).
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