Gas Exchange and Fluid Regulation Chapter 42

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Questions and Answers

What is the primary function of the sodium-potassium pump in the proximal tubule?

  • To create a sodium gradient (correct)
  • To increase potassium levels in the urine
  • To decrease sodium levels in the blood
  • To balance water levels in the filtrate

How does the ascending loop of Henle primarily transport salts from the filtrate?

  • By passive transport only
  • Using diffusion alone
  • Through osmosis only
  • Through both active and passive transport (correct)

Which parameter is NOT a factor in Frick’s Law of Diffusion?

  • Concentration gradient
  • Membrane permeability
  • Molecular weight of the gas (correct)
  • Thickness of the barrier

What role does the antidiuretic hormone (ADH) play in the kidneys?

<p>It saves water by increasing permeability in collecting ducts (A)</p> Signup and view all the answers

What unique feature do fish gills utilize for efficient gas exchange?

<p>Countercurrent exchange system (A)</p> Signup and view all the answers

What is the typical resting membrane potential of a neuron?

<p>-65 mV (A)</p> Signup and view all the answers

What primarily causes the negative resting membrane potential in neurons?

<p>Higher concentration of negatively charged ions inside the cell (A)</p> Signup and view all the answers

During which stage of action potential do sodium channels quickly open?

<p>Depolarization (B)</p> Signup and view all the answers

What is the primary role of the sodium-potassium pump in resting neurons?

<p>To actively transport Na+ out and K+ in (D)</p> Signup and view all the answers

What is the effect of potassium ions leaking out of a neuron during resting potential?

<p>It contributes to maintaining a negative membrane potential. (A)</p> Signup and view all the answers

What is the correct pathway for lipid soluble signaling molecules after they diffuse into the cytosol?

<p>They form a hormone-receptor complex and are transported to the nucleus. (D)</p> Signup and view all the answers

Which type of signaling molecules requires the presence of hydrophilic carriers in the bloodstream?

<p>Lipid soluble hormones. (D)</p> Signup and view all the answers

How is the signal transduction process characterized?

<p>Conversion of an extracellular signal into an intracellular signal. (A)</p> Signup and view all the answers

What is NOT a consequence of receptor blocking by drugs?

<p>Increased activity of the target proteins. (B)</p> Signup and view all the answers

What is the first step in processing lipid soluble signaling molecules?

<p>Diffusion of the hormone across the plasma membrane. (B)</p> Signup and view all the answers

Which of the following best describes ligand-gated ion channels?

<p>They require a ligand to change their conformation and allow ion passage. (C)</p> Signup and view all the answers

What ultimately results from the interaction of the intracellular signaling molecule with DNA?

<p>Altered gene expression. (A)</p> Signup and view all the answers

What role do relay molecules play in the signal transduction pathway?

<p>They amplify the signal as it moves down the pathway. (D)</p> Signup and view all the answers

What is the main event occurring during the G2 phase of the cell cycle?

<p>Increased synthesis of proteins and organelles (C)</p> Signup and view all the answers

Which structure is formed from hollow tubes made of alpha and beta subunits during the cell cycle?

<p>Microtubules (C)</p> Signup and view all the answers

During which phase does the nuclear membrane completely break down?

<p>Prometaphase (D)</p> Signup and view all the answers

What structure forms in animal cells to initiate cytokinesis?

<p>Cleavage furrow (A)</p> Signup and view all the answers

Which phase of the cell cycle is characterized as the 'resting state'?

<p>G0 Phase (A)</p> Signup and view all the answers

What significant change occurs during anaphase?

<p>Sister chromatids become true chromosomes (B)</p> Signup and view all the answers

What is required at the G1/S checkpoint for a cell to proceed in the cycle?

<p>Adequate ATP levels (B)</p> Signup and view all the answers

Which component is responsible for attaching to kinetochores during prometaphase?

<p>Kinetochore microtubules (D)</p> Signup and view all the answers

What is the primary role of cyclins in the cell cycle?

<p>To initiate the synthesis of cyclin-dependent kinases (CDKs) (B)</p> Signup and view all the answers

Which statement regarding CDK is correct?

<p>CDK acts as a regulatory enzyme by phosphorylating other proteins (B)</p> Signup and view all the answers

What is a characteristic of malignant tumors?

<p>They can invade other tissue types and may cause metastasis (A)</p> Signup and view all the answers

Which factor is NOT essential for cell division to occur?

<p>Mature cells having the ability to divide (B)</p> Signup and view all the answers

What checkpoint assesses if all chromosomes are properly attached to the mitotic spindle?

<p>Late metaphase (spindle) checkpoint (D)</p> Signup and view all the answers

What is the role of E2F in the cell cycle?

<p>To activate the G1 checkpoint for cell cycle progression (D)</p> Signup and view all the answers

Which condition is associated with cancerous cells?

<p>They remain immortal and can divide indefinitely (C)</p> Signup and view all the answers

How does PDGF function during tissue injury?

<p>It promotes cell division to facilitate wound healing (A)</p> Signup and view all the answers

What is the function of the proton-sucrose symporter in the companion cell?

<p>To bring in hydrogen ions and sucrose together (B)</p> Signup and view all the answers

How do developing leaf cells acquire sucrose?

<p>Through passive transport following the sucrose concentration gradient (D)</p> Signup and view all the answers

Which type of soil ions are immediately available for plant use?

<p>Anions that dissolve in soil water (B)</p> Signup and view all the answers

What role do mycorrhizal fungi play in nutrient uptake for plants?

<p>They enhance nutrient availability by increasing root surface area (A)</p> Signup and view all the answers

What is the correct order of the processes through which animals obtain nutrients?

<p>Ingestion, Digestion, Absorption, Elimination (A)</p> Signup and view all the answers

Which jaw adaptation is characteristic of a filter feeder?

<p>Using a sieve-like structure to filter food from water (D)</p> Signup and view all the answers

What happens when hydrogen ions leave the vacuole of the sink cell?

<p>They exit through a proton-sucrose antiporter to bring in sucrose (A)</p> Signup and view all the answers

How do hydrogen pumps in root cells assist in nutrient uptake?

<p>They create electrochemical gradients to facilitate ion transport (D)</p> Signup and view all the answers

What is the primary role of microvilli in the small intestines?

<p>To enhance the absorption efficiency of nutrients (A)</p> Signup and view all the answers

Which process is involved in the breakdown of lipids in the digestive system?

<p>Lingual lipase breakdown (B)</p> Signup and view all the answers

How do osmoregulators maintain constant molarity within their bodies?

<p>Through active transport that utilizes ATP (D)</p> Signup and view all the answers

What is the primary function of the large intestines?

<p>To compact waste and absorb water to form feces (A)</p> Signup and view all the answers

Which nitrogenous waste is most toxic and requires the least amount of energy to produce?

<p>Ammonia (D)</p> Signup and view all the answers

What advantage do osmoconformers have in stable ocean habitats?

<p>They require less energy to maintain constant osmolarity. (B)</p> Signup and view all the answers

Which of the following is NOT a step in the chemical digestion of food?

<p>Absorption of nutrients in the stomach (C)</p> Signup and view all the answers

What defines the metabolic rate in animals?

<p>The energy used per unit of time (C)</p> Signup and view all the answers

Flashcards

Proximal Tubule Sodium Reabsorption

Sodium is actively pumped out of the filtrate into the blood, creating a concentration gradient.

Descending Loop of Henle Function

Water passively moves out of the filtrate, making it more concentrated

Ascending Loop of Henle Function

Salts move out of the filtrate, either passively or actively, following a concentration gradient.

Gas Exchange Principle

Gas exchange across a surface depends upon diffusion driven by differences in partial pressure and other factors.

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Countercurrent Exchange System

Blood and water flow in opposite directions to maximize gas or salt exchange.

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Receptor Blockage

Drugs can prevent hormones from binding to their receptors, disrupting signaling pathways.

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Signal Processing Location

The cell's response to a signal depends on whether the receptor is on the cell membrane or inside the cytosol.

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Lipid-Soluble Hormones

Hormones like estrogen, testosterone, and cortisol can directly pass through the cell membrane.

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Hormone-Receptor Complex

A complex formed when a lipid-soluble hormone binds to its receptor inside the cell. This complex triggers changes in gene expression.

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Lipid-Insoluble Hormones

These hormones cannot directly enter the cell and require signal transduction pathways to relay their message.

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Signal Transduction

The process of converting an extracellular signal into an intracellular signal, often amplified along the way.

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Ligand-Gated Ion Channel

A type of receptor that opens an ion channel when a signaling molecule (ligand) binds to it.

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Phosphorylation Cascades

A series of protein activations by adding phosphate groups, often used in signal transduction pathways.

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G2 Phase

The stage in the cell cycle where the cell grows and synthesizes proteins, mitochondria, and other organelles. This prepares the cell for mitosis.

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G1/S Checkpoint

A checkpoint in the cell cycle that checks for sufficient nutrients, favorable environmental conditions, and proper growth factors. This ensures the cell is ready to replicate its DNA.

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Microtubule-Organizing Centers

Structures within the cytoplasm that form during G2 and are responsible for organizing microtubule formation, which are essential for cell division (mitosis).

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Actin Filaments

Thin fibers responsible for cell movement, contraction, and the separation of animal cells during cytokinesis. They form two coiled strands.

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Intermediate Filaments

Strong, rope-like fibers that provide structural support to cells. They are thicker than actin filaments.

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Microtubules

Hollow tubes made of alpha and beta subunits that are involved in cell shape, organelle transport, and the formation of the mitotic spindle.

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Prophase

The first stage of mitosis where the nuclear envelope starts dissolving, chromosomes condense, and sister chromatids become visible.

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Prometaphase

The stage of mitosis where the nuclear membrane completely dissolves, kinetochores attach to microtubules, and the mitotic spindles move to the cell poles.

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Resting Membrane Potential

The electrical charge difference across a neuron's membrane when it's not actively transmitting a signal. It's usually negative due to more negative ions inside the cell compared to outside.

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Sodium-Potassium Pump

A protein embedded in the neuron's membrane that actively pumps sodium ions out and potassium ions into the cell, creating a concentration gradient.

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Depolarization

The initial phase of an action potential where the membrane potential becomes less negative, moving towards a more positive charge. It's triggered by sodium ions rushing into the cell.

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Threshold Potential

The minimum level of depolarization required to trigger an action potential. If the membrane potential doesn't reach this threshold, no signal is sent.

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Action Potential

A rapid temporary change in the membrane potential of a neuron, caused by the flow of ions across the membrane. It's the way neurons communicate.

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MPF (Maturation Promoting Factor)

A complex of cyclin and cyclin-dependent kinase (CDK) that drives the cell from G2 phase into M phase (mitosis). It activates a cascade of proteins that ultimately leads to cell division.

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CDK (Cyclin-Dependent Kinase)

An enzyme that, when bound to cyclin, phosphorylates other proteins to trigger different stages of the cell cycle. CDK activity is regulated by the presence and concentration of cyclin.

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Cyclin

A protein that activates CDK and whose concentration fluctuates throughout the cell cycle. Different cyclins are responsible for each phase of the cell cycle.

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RB (Retinoblastoma Protein)

A tumor suppressor protein that when unphosphorylated, binds to E2F (a transcription factor) and blocks the cell cycle from entering S phase (DNA replication).

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E2F

A transcription factor that activates the expression of genes involved in DNA replication and cell division.

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Late Metaphase (Spindle) Checkpoint

A checkpoint in the cell cycle that ensures that all chromosomes are properly attached to microtubules of the spindle apparatus before the cell divides.

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Phloem Loading

The process of moving sugars from source cells (like leaves) to companion cells in the phloem.

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Proton-Sucrose Symporter

A protein in the companion cell membrane that actively transports both hydrogen ions and sucrose into the cell, using energy from the proton gradient.

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Turgor Pressure

The pressure exerted by the fluid inside the phloem cells, pushing the sap towards sink cells.

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Phloem Unloading

The process of moving sugars from the companion cells to the sink cells, where they are used or stored.

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Tonoplast

The membrane that surrounds the large vacuole in root cells, playing a role in controlling the movement of sucrose.

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Proton-Sucrose Antiporter

A protein in the tonoplast that uses the electrochemical gradient to bring sucrose into the vacuole while exporting hydrogen ions.

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Mycorrhizal Fungi

Fungi that form a symbiotic (mutually beneficial) relationship with plant roots, helping them absorb nutrients.

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Nutrient Uptake by Roots

The process of roots absorbing essential nutrients from the soil, using active and passive transport mechanisms.

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Pharyngeal Jaw

A second set of jaws found in some fish, located in the throat, used for crushing and grinding food.

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Cichlid's Pharyngeal Jaw

Cichlids have a pharyngeal jaw that bites more effectively due to the arrangement and specialization of its teeth.

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What is the role of salivary amylase?

Salivary amylase is an enzyme in saliva that begins the breakdown of carbohydrates in the mouth.

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Lingual Lipase

Lingual lipase is an enzyme found in the mouth that starts breaking down lipids (fats).

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Pepsin

Pepsin is an enzyme in the stomach responsible for breaking down proteins into smaller peptides.

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Osmoconformer

An animal that maintains the same internal osmolarity as its surrounding environment, requiring less energy to regulate.

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Osmoregulator

An animal that actively regulates its internal osmolarity, maintaining a constant concentration even when the external environment changes.

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Nitrogenous Waste: Urea (Mammals)

Urea is a moderately soluble, moderately toxic form of nitrogenous waste produced by mammals.

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Study Notes

Proximal Tubule Lumen

  • Sodium-potassium pump moves sodium out to blood vessels and potassium in.
  • Goal: Establish a sodium gradient.

Loop of Henle

  • Descending loop: Filtrate moves down, water passively moves out (filtrate concentrates).
  • Ascending loop: Salts move out through concentration gradients (passive and active transport).
  • Henle loop descends again (ADH comes into play).

Antidiuretic Hormone (ADH)

  • ADH conserves water in the collecting ducts by making them more permeable.
  • Water leaves the loop of Henle more than usual.

Gas Exchange (Chapter 42)

  • Homeostasis depends on respiratory and circulatory systems.
  • Gas Exchange Steps:
    • Ventilation
    • Diffusion
    • Circulation
    • Diffusion
    • Cellular respiration
  • Organisms obtain oxygen and release carbon dioxide through diffusion.

Gas Exchange in Water

  • Gases dissolve in water from the atmosphere, influenced by several factors.
  • Fick's Law of Diffusion:
    • Rate of diffusion depends on:
      • Gas solubility
      • Temperature
      • Surface area for diffusion
      • Partial pressure differences across the exchange surface
      • Thickness of the diffusion barrier
  • Increased surface area, decreased membrane thickness, increased concentration gradient, or increased membrane permeability increase diffusion through membranes.

Aquatic Organisms

  • Not all aquatic organisms have gills; some use simple diffusion through skin.

Gills in Aquatic organisms

  • Parapodia in some: Function as gills.
  • Coeloms in others: Gills embedded in coelom (e.g., starfish).
  • Fish gills: Countercurrent exchange system (blood flows opposite to water flow).
  • Warm blood transfers heat to adjacent veins.

Billfish

  • Heater cells warm up neurons in eye cells.

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