Gas Chromatography Instrumentation

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18 Questions

What is the typical internal diameter range of a capillary column in gas chromatography?

0.1 - 0.53 mm

Which chemical compound is commonly analyzed using a DB-5MS stationary phase in gas chromatography?

Cannabinoids

When might a narrow-bore column be used in gas chromatography?

When a fast capillary column is required

What is the primary disadvantage of gas chromatography compared to other analytical techniques?

Long analysis times

Which application area commonly uses DB-1 as the stationary phase in gas chromatography?

Forensic applications

What is the advantage of using a 0.25 mm i.d. capillary column in gas chromatography?

Reduced column overload

What is the purpose of the polymer coating on a capillary GC column?

To provide rigidity and flexibility to the column

Which parameter is critical for a scientist to consider when selecting a column for capillary GC?

Length of the capillary column

What role does the internal diameter of the column play in gas chromatography?

It affects compound separation efficiency

What is a disadvantage associated with using a capillary GC column?

Limited sample capacity

Which feature distinguishes capillary GC columns from packed GC columns?

Length and internal diameter

What advantage does capillary GC offer over packed GC columns?

Faster analysis time

What are the main instrumental components of a gas chromatograph?

Gas supply, Sample introduction system, Column oven, Column, Detector, Read-out device

What is a key aspect that determines the performance of a gas chromatography system?

Choice of carrier gas

Why is nitrogen commonly used as the carrier gas in gas chromatography with a flame ionization detector?

Availability and efficiency

What is the main advantage of using helium as the carrier gas with a mass spectrometer detector?

Increased sensitivity

Which plot can be used to assess the efficiency of a gas chromatograph?

van Deemter plot

Besides integration and display of peak area and peak height, what are some other variables typically available in gas chromatography instrumentation?

Retention time determination parameters

This quiz covers the main instrumental components of a gas chromatograph, including the gas supply, sample introduction system, column oven, column detector, and read-out device. The read-out device typically consists of a computer with software for integration and display of peak area and peak height.

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