Gallstones and Their Incidence

LikableKineticArt avatar
LikableKineticArt
·
·
Download

Start Quiz

Study Flashcards

Questions and Answers

What is the role of pronucleating factors in gallstone formation?

Stabilize cholesterol-laden phospholipid vesicles

What is the composition of pigment stones?

Black to dark brown, 2-5 mm in diameter, and amorphous

Why do gallstones form almost exclusively in the gallbladder?

The gallbladder concentrates the bile

What is the effect of specific bile proteins on cholesterol crystal formation?

<p>Stabilize cholesterol-laden phospholipid vesicles</p> Signup and view all the answers

What is the role of antinucleating factors in gallstone formation?

<p>Glycoprotein, apolipoprotein, cytokeratin</p> Signup and view all the answers

What percentage of common duct stones are cholesterol stones?

<p>60%</p> Signup and view all the answers

Which type of common duct stones is associated with more severe clinical manifestations?

<p>Pigment stones</p> Signup and view all the answers

How many patients with choledocholithiasis may remain asymptomatic?

<p>50%</p> Signup and view all the answers

What percentage of patients with gallbladder stones will have common duct stones?

<p>15%</p> Signup and view all the answers

What might develop in patients with biliary tumors?

<p>Truly huge ducts</p> Signup and view all the answers

What is the prognosis for death rate from gallstone ileus?

<p>20%</p> Signup and view all the answers

What is the percentage of patients requiring interval cholecystectomy?

<p>30%</p> Signup and view all the answers

What is the origin of most common duct stones?

<p>Gallbladder</p> Signup and view all the answers

What is the percentage of patients with stones in the gallbladder harboring calculi within the bile ducts?

<p>15%</p> Signup and view all the answers

What is the percentage of cases where the gallbladder is empty but there are duct stones?

<p>5%</p> Signup and view all the answers

What is the primary composition of pigment gallstones?

<p>Dense mixtures of bacteria and bacterial glycocalyx</p> Signup and view all the answers

Which factor is NOT listed as a predisposing factor for pigment gallstones?

<p>Obesity</p> Signup and view all the answers

What is the radiopacity percentage of pigment gallstones?

<p>50%</p> Signup and view all the answers

What role do bacteria likely play in the formation of pigment gallstones?

<p>Converting soluble bilirubin to insoluble unconjugated bilirubin</p> Signup and view all the answers

Which ethnic group is mentioned as having a lower incidence of pigment stones?

<p>American Indians</p> Signup and view all the answers

What is the primary composition of pigment stones?

<p>Bacteria and bacterial glycocalyx</p> Signup and view all the answers

What role do bacteria play in the formation of pigment gallstones?

<p>They deconjugate the soluble bilirubin­diglucuronide into insoluble unconjugated bilirubin</p> Signup and view all the answers

What is a common predisposing factor for pigment gallstones?

<p>Chronic hemolysis</p> Signup and view all the answers

What is the radiopacity percentage of pigment stones in the United States?

<p>50%</p> Signup and view all the answers

What is the probable cause of sepsis being more common in patients with pigment gallstone disease than in those with cholesterol gallstone disease?

<p>Increased bacterial β­glucuronidase activity</p> Signup and view all the answers

What is the composition of the majority of gallstones in patients?

<p>Cholesterol stones</p> Signup and view all the answers

How do cholesterol gallstones form in the body?

<p>By precipitation of cholesterol from bile supersaturated with cholesterol</p> Signup and view all the answers

Where do the stones in cholesterol gallstone disease typically form?

<p>Exclusively within the gallbladder</p> Signup and view all the answers

Which population group has the highest incidence of cholesterol gallstone disease?

<p>American Indians</p> Signup and view all the answers

How does hormonal effect relate to the incidence of gallstones?

<p>Increased estrogen levels are associated with greater cholesterol saturation of bile and increased incidence of gallstones</p> Signup and view all the answers

Which of the following is a common symptom of acute cholecystitis?

<p>Right upper quadrant pain</p> Signup and view all the answers

What is a characteristic finding in sonographic imaging of acute cholecystitis?

<p>Gallbladder distension</p> Signup and view all the answers

What is the primary cause of acute cholecystitis in 80% of cases?

<p>Gallstone obstruction in the cystic duct</p> Signup and view all the answers

What is a common indicator of acute cholecystitis in laboratory tests?

<p>Leukocytosis</p> Signup and view all the answers

What is a possible finding in a nonopacified gallbladder on radionuclide excretion scan?

<p>Gallbladder shrinkage</p> Signup and view all the answers

What is a potential physical examination finding in acute cholecystitis?

<p>Palpable gallbladder</p> Signup and view all the answers

In acute cholecystitis, what contributes to the creation of abdominal pain and tenderness?

<p>Gallbladder inflammation and distention</p> Signup and view all the answers

What is a characteristic feature of the Sonographic Murphy sign in acute cholecystitis?

<p>Gallbladder distension</p> Signup and view all the answers

What is a common finding in gallbladder wall imaging in acute cholecystitis?

<p>&quot;Thickening&quot; of the gallbladder wall</p> Signup and view all the answers

What is a potential finding in the presence of pericholecystic fluid in acute cholecystitis?

<p>&quot;Rim sign&quot; around the gallbladder</p> Signup and view all the answers

More Quizzes Like This

Liver Disease and Gallstones Quiz
5 questions
Epidemiology of Gallstones
10 questions
Use Quizgecko on...
Browser
Browser