Gallstone Disease Diagnosis
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Questions and Answers

What is the treatment of choice for symptomatic gallstone disease?

  • Opioid analgesics
  • Total parenteral nutrition
  • Sphincter of Oddi dilation
  • Laparoscopic cholecystectomy (correct)
  • What is the pathogenesis of biliary colic?

  • Sphincter of Oddi dysfunction
  • Gallbladder stasis
  • Gallstone ileus
  • Gallbladder contraction against a gallstone that temporarily blocks the cystic duct (correct)
  • What is the diagnosis of gallstone disease confirmed with?

  • Liver function studies
  • Abdominal ultrasound (correct)
  • Endoscopic retrograde cholangiopancreatography
  • Abdominal CT scan
  • What is a complication of total parenteral nutrition?

    <p>Gallbladder stasis and gallstone formation</p> Signup and view all the answers

    What is the characteristic of gallstone ileus?

    <p>Small bowel obstruction due to a gallstone that has passed through a biliary-enteric fistula</p> Signup and view all the answers

    What is the effect of opioid analgesics on the sphincter of Oddi?

    <p>Contraction</p> Signup and view all the answers

    What is the characteristic of symptoms in biliary colic?

    <p>Episodic postprandial right upper quadrant or epigastric pain</p> Signup and view all the answers

    What is the management of gallstone ileus?

    <p>Surgical removal of the stone and cholecystectomy</p> Signup and view all the answers

    Study Notes

    Gallstone Disease

    • Asymptomatic gallstones do not require treatment.
    • Laparoscopic cholecystectomy is the preferred treatment for symptomatic gallstone disease.

    Biliary Colic

    • Biliary colic occurs when the gallbladder contracts against a gallstone that temporarily blocks the cystic duct.
    • Classic symptoms of biliary colic include:
      • Episodic postprandial right upper quadrant or epigastric pain
      • Nausea
      • Vomiting
    • Notably, vital signs, white blood cell count, and liver function studies remain normal.
    • Diagnosis is confirmed with an abdominal ultrasound demonstrating the presence of gallstones.

    Sphincter of Oddi Dysfunction

    • Sphincter of Oddi dysfunction is a functional biliary disorder due to dyskinesia or stenosis of the sphincter of Oddi.
    • Symptoms include:
      • Recurrent, episodic pain in the right upper quadrant or epigastric region
      • Corresponding elevations in aminotransferases and alkaline phosphatase
    • Opioid analgesics (e.g., morphine) may cause sphincter contraction and precipitate symptoms.

    Gallstone Ileus

    • Gallstone ileus results from small bowel obstruction due to a gallstone that has passed through a biliary-enteric fistula.
    • The stone may cause "tumbling" obstruction before ultimately causing complete obstruction.
    • Treatment involves surgical removal of the stone and cholecystectomy.

    Total Parenteral Nutrition and Gallstone Formation

    • Total parenteral nutrition causes gallbladder stasis, predisposing to:
      • Gallstone formation
      • Bile sludging
    • These conditions may lead to cholecystitis.

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    Description

    Learn about the diagnosis and treatment of gallstone disease, including asymptomatic and symptomatic cases.

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