Galenical Dosage Forms Quiz
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Questions and Answers

What is the primary focus of galenical preparations?

  • Isolating active ingredients from natural products
  • Formulating pharmaceuticals from natural sources (correct)
  • Developing new routes of administration
  • Preparing drugs from synthetic sources

What is the term 'galenicals' named after?

  • A Roman physician
  • Claudius Galen (correct)
  • A Greek philosopher
  • A medieval alchemist

What is the purpose of maceration in galenical preparation?

  • To isolate active ingredients from natural products
  • To filter out impurities from extracts
  • To dry plant material for storage
  • To mix plant material with a menstruum (correct)

Why are galenical preparations still relevant today?

<p>Because isolation of active ingredients can be expensive and labour intensive (D)</p> Signup and view all the answers

What is the purpose of percolation in galenical preparation?

<p>To extract active ingredients from plant material (C)</p> Signup and view all the answers

How long does the maceration process typically take?

<p>7 days (B)</p> Signup and view all the answers

What is the process called when the solvent is kept hot during maceration?

<p>Digestion (B)</p> Signup and view all the answers

What is the main limitation of maceration when water is used as the solvent?

<p>It may allow fungal growth during the long period of maceration (A)</p> Signup and view all the answers

What is the purpose of pre-treating the material before packing it into a percolator?

<p>To ensure the cells are hydrated and swollen (D)</p> Signup and view all the answers

What is repeat maceration?

<p>A process where the marc is macerated a second time and the strained liquids are combined (B)</p> Signup and view all the answers

What is the limitation of digestion?

<p>It may not be used when components are volatile or susceptible to thermal degradation (D)</p> Signup and view all the answers

What is the distinction between maceration and percolation?

<p>Maceration is a time-consuming process while percolation is a short process (B)</p> Signup and view all the answers

What is the advantage of using expression in processing thermolabile compounds?

<p>It generates very little heat (A)</p> Signup and view all the answers

What is the main difference between a fresh infusion and a concentrated infusion?

<p>The concentration of the active principle (D)</p> Signup and view all the answers

What is the purpose of the perforated inner container in a simple single screw press?

<p>To allow drainage of the liquid (B)</p> Signup and view all the answers

What is the limitation of using expression in extraction?

<p>It is only used for soft compressible materials (A)</p> Signup and view all the answers

What is the main characteristic of extracts?

<p>They contain a higher proportion of the active principle (C)</p> Signup and view all the answers

What is the purpose of maceration in the preparation of infusions?

<p>To extract the active principle (D)</p> Signup and view all the answers

What is the primary purpose of standardizing galenicals?

<p>To ensure adequate uniform potency (B)</p> Signup and view all the answers

What type of method measures biological effects such as heart rate and blood pressure?

<p>Biological method (B)</p> Signup and view all the answers

Which of the following is an example of a galenical prepared by percolation?

<p>Compound Cardamom 28 Tincture (A)</p> Signup and view all the answers

What is the purpose of arbitrary methods in standardizing galenicals?

<p>To determine the organoleptic characters of galenicals (B)</p> Signup and view all the answers

Which of the following is a chemical method used in standardizing galenicals?

<p>Titration (A)</p> Signup and view all the answers

What is the purpose of adding alcohol to tinctures?

<p>To confer preservation on tinctures (D)</p> Signup and view all the answers

What is the term for extracts prepared with ether?

<p>Ethereal extract (C)</p> Signup and view all the answers

What is the purpose of evaporation after filtration?

<p>To obtain a thick mass or solid extract (B)</p> Signup and view all the answers

What is the range of alcohol concentrations commonly used in tinctures?

<p>45-90% v/v (D)</p> Signup and view all the answers

What is the term for extracts that are not standardized?

<p>Non-standardized extract (D)</p> Signup and view all the answers

What is the method of preparation for tinctures prepared by admixture?

<p>Simple admixture (D)</p> Signup and view all the answers

Flashcards

Galenical preparations

Pharmaceutical preparations made from natural sources, named after Claudius Galen.

Maceration

Mixing plant material with a solvent (menstruum) for a period to extract active ingredients.

Digestion (maceration)

Maceration with a heated solvent.

Percolation

Extracting active ingredients from plant material by allowing a solvent to pass slowly through it.

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Repeat maceration

Macerating the remaining plant matter (marc) a second time to obtain more active ingredients, combining with previous extracts.

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Expression

Method of extracting compounds from soft, compressible materials by physical pressure.

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Infusion

A liquid preparation made by steeping plant material in hot or cold water.

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Concentrated Infusion

Infusion with a higher concentration of active principle compared to a fresh infusion.

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Extract

Concentrated preparation containing a higher proportion of the active principle compared to the original material.

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Standardization of Galenicals

Ensuring uniform potency and quality in galenicals.

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Biological method

Method to measure biological effects like heart rate and blood pressure.

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Chemical method

Method using chemical analysis or reactions to determine constituents, such as titration.

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Tincture

Liquid preparations made by extracting active constituents of a substance using alcohol.

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Ethereal extract

Extract made with ether.

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Non-standardized extract

Extract without specified standards to ensure potency/quality.

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Simple admixture

Method to produce tinctures by mixing ingredients together.

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Limitation of maceration (water)

Using water as a solvent can promote fungal growth during long maceration times.

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Limitation of Digestion

Not suitable for volatile or thermally sensitive compounds.

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Limitation of Expression

Only suitable for soft, compressible materials.

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Maceration vs. Percolation

Maceration is a prolonged soaking, percolation is a continuous method of solvent passage through the material

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Advantage of Expression

Generates very little heat.

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Purpose of arbitrary methods

Determine the organoleptic qualities (senses) of galenicals.

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Purpose of pre-treating material before percolation

Ensures the plant cells are properly hydrated and large enough for effective extraction.

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Purpose of adding alcohol to tinctures

Preserves the tincture and prevents decay.

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