GABER, PHD 4 & 5: Semi-Solid Preparations Quiz

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17 Questions

What are the disadvantages associated with packaging semisolids in tubes?

Bacterial contamination, product oxidation, increase in water loss

Which of the following materials are commonly used for making tubes for semisolids?

Aluminum and plastic

What coatings are applied to aluminum tubes to prevent interaction with components?

Epoxy resin or vinyl

Which tube sizes are commonly used for semisolid preparations?

5, 15, 30 g tubes

What is the approximate weight of ophthalmic semisolid preparation tubes?

~3.5 g

Which feature makes tubes a preferable choice over jars for packaging semisolids?

Greater protection against external contamination and environmental conditions

What makes aluminum tubes suitable for packaging semisolid preparations?

Lightweight and chemically inert

Thixotropy in gels refers to the ability of the gel to become ______ when sheared and regain its viscosity when the shearing force is removed.

fluid

______ is the expulsion of liquid from a gel upon standing or aging.

Syneresis

The process of ______ occurs when a polymer matrix swells and absorbs water or another solvent.

imbibition

To prepare a carbopol gel, the polymer is first dispersed in ______ before neutralizing with a base.

water

The pH of the dispersion medium can affect the ______ of the polymer chains in a hydrophilic gel.

ionization

Preparation conditions, such as ______, can influence the final properties of a gel.

temperature

The concentration of the gelling agent plays a crucial role in determining the ______ of the resulting gel.

viscosity

Carbopol gels are typically prepared by first dispersing the polymer in water and then ______ with a base.

neutralizing

The rate of ______ can affect the swelling and gel formation process.

stirring

Gels can exhibit ______ behavior, where they can flow under shear stress and regain their structure when the stress is removed.

thixotropic

Test your knowledge on the preparation of pastes and creams in semi-solid preparations according to lectures by Dr. Dina M. Gaber. Learn about the methods used to prepare pastes and the characteristics of creams as semisolid emulsions.

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