GABER, PHD 4 & 5: Semi-Solid Preparations Quiz

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Questions and Answers

What are the disadvantages associated with packaging semisolids in tubes?

  • Aluminum corrosion, plastic degradation, loss of formulation components
  • Bacterial contamination, product oxidation, increase in water loss (correct)
  • Product leakage, tube breakage, incompatibility with formulation components
  • Water absorption, reduced product shelf life, environmental hazards

Which of the following materials are commonly used for making tubes for semisolids?

  • Aluminum and plastic (correct)
  • Titanium and silicone
  • Ceramic and cardboard
  • Glass and steel

What coatings are applied to aluminum tubes to prevent interaction with components?

  • Polyethylene or polypropylene
  • Rubber or latex
  • Epoxy resin or vinyl (correct)
  • Polystyrene or acrylic

Which tube sizes are commonly used for semisolid preparations?

<p>5, 15, 30 g tubes (A)</p> Signup and view all the answers

What is the approximate weight of ophthalmic semisolid preparation tubes?

<p>~3.5 g (C)</p> Signup and view all the answers

Which feature makes tubes a preferable choice over jars for packaging semisolids?

<p>Greater protection against external contamination and environmental conditions (A)</p> Signup and view all the answers

What makes aluminum tubes suitable for packaging semisolid preparations?

<p>Lightweight and chemically inert (A)</p> Signup and view all the answers

Thixotropy in gels refers to the ability of the gel to become ______ when sheared and regain its viscosity when the shearing force is removed.

<p>fluid</p> Signup and view all the answers

______ is the expulsion of liquid from a gel upon standing or aging.

<p>Syneresis</p> Signup and view all the answers

The process of ______ occurs when a polymer matrix swells and absorbs water or another solvent.

<p>imbibition</p> Signup and view all the answers

To prepare a carbopol gel, the polymer is first dispersed in ______ before neutralizing with a base.

<p>water</p> Signup and view all the answers

The pH of the dispersion medium can affect the ______ of the polymer chains in a hydrophilic gel.

<p>ionization</p> Signup and view all the answers

Preparation conditions, such as ______, can influence the final properties of a gel.

<p>temperature</p> Signup and view all the answers

The concentration of the gelling agent plays a crucial role in determining the ______ of the resulting gel.

<p>viscosity</p> Signup and view all the answers

Carbopol gels are typically prepared by first dispersing the polymer in water and then ______ with a base.

<p>neutralizing</p> Signup and view all the answers

The rate of ______ can affect the swelling and gel formation process.

<p>stirring</p> Signup and view all the answers

Gels can exhibit ______ behavior, where they can flow under shear stress and regain their structure when the stress is removed.

<p>thixotropic</p> Signup and view all the answers

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