Future University in Egypt Login

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Questions and Answers

What is the purpose of the 'Log in to Future University in Egypt' section?

To access university resources (correct)

To download the mobile app

To request IT support

To submit a form on Microsoft

What happens when a user's session times out?

The user's data is lost

The user is prompted to log in again (correct)

The user is redirected to the homepage

The user is blocked from accessing the site

What is the contact information provided for IT-related inquiries?

An email address (correct)

A contact form

A phone number

A physical address

What can be done in case of a lost password?

Reset password using the 'Lost password' link Signup and view all the answers

What is the purpose of the 'Cookies notice' section?

To inform users about cookie usage Signup and view all the answers

What is the alternative way to access university resources mentioned on the page?

The mobile app Signup and view all the answers

What is the most common type of depression?

Unipolar depression Signup and view all the answers

What is the percentage of men who are affected by depression?

8% Signup and view all the answers

What is the role of proinflammatory cytokines such as IL-6, IL-1 and TNF-α in depression?

They contribute to the pathophysiology of depression Signup and view all the answers

What is the 'Biogenic Amine Theory' of depression?

Depression is caused by a functional defect of monamine transmitters Signup and view all the answers

What is the difference between Unipolar depression and Bipolar depression?

Unipolar depression has no alternate episodes of depression and mania, while Bipolar depression does Signup and view all the answers

How many genes related to depression have been identified so far?

4 Signup and view all the answers

What is the main function of MAO-A enzymes in the brain?

Breakdown of NE, 5-HT, and dopamine Signup and view all the answers

What is the effect of MAOIs on the degradation of neurotransmitters?

Decrease the degradation of NE and 5-HT Signup and view all the answers

What is the primary use of MAOIs in antidepressant treatment?

Alternative treatment for patients unresponsive to TCAs or SSRIs Signup and view all the answers

What is the delay in the antidepressant effect of MAOIs?

More than 2 weeks Signup and view all the answers

What is the duration of the antidepressant effect of MAOIs after stopping the drug?

2-3 weeks Signup and view all the answers

What is the main difference between MAO-A and MAO-B enzymes?

MAO-A is responsible for breaking down NE, 5-HT, and dopamine, while MAO-B is responsible for breaking down dopamine only Signup and view all the answers

What is the mechanism of action of MAOIs in relation to neurotransmitters?

Inhibit the breakdown of neurotransmitters by MAO enzymes Signup and view all the answers

What is the limitation of MAOIs in antidepressant treatment?

Risk of drug-drug interaction and drug-food interactions Signup and view all the answers

Study Notes

Future University in Egypt Website

Website has a login feature for users to access their accounts
Session timeout is implemented for security purposes
Users are prompted to log in again after a session timeout
Login credentials include a username or email and a password
A "Lost password?" feature is available for users who forgot their passwords
Contact information for the Information Technology Department is provided, including an email address and a form (Microsoft Form)

Cookies Notice

The website uses cookies, and a notice is displayed to users about this
No further information is provided about the cookies policy

Depression

Depression is a CNS disorder affecting mood, with women being more prone to it (16%) than men (8%).
There are 2 types of depression: Unipolar depression (major depressive disorder) and Bipolar depression (manic-depressive disorder).

Pathophysiology of Depression

Genetics: 4 genes related to depression have been identified.
Biogenic amine and receptor theory: Decrease in brain-derived neurotrophic factor (BDNF) and hypothalmo-pituitary axis dysregulation.
Neurotrophic and cytokines theory: Proinflammatory cytokines such as IL-6, IL-1, and TNF-α play a role.

Biogenic Amine Theory

Depression is caused by a functional defect of monamine transmitters (NE and/or 5-HT) in the brain, while mania results from a functional excess.

Symptoms of Depression

Emotional symptoms: Loss of interest, apathy, loss of self-esteem, and loss of motivation.
Biological symptoms: Sleep disturbance, loss of libido, and chronic pain.

Anti-Depressant Drugs

Classified into:
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants (TCAs)
- Selective serotonin reuptake inhibitors (SSRIs)
- Serotonin-norepinephrine reuptake inhibitors (SNRIs)
- Atypical heterocyclic antidepressant drugs

Monoamine Oxidase Inhibitors (MAOIs)

The oldest class of antidepressant drugs.
MAO-A and MAO-B are two types of monoamine oxidase enzymes.
MAO-A is responsible for breakdown of NE, 5-HT, and dopamine, while MAO-B is mainly responsible for breakdown of dopamine.
MAOIs inactivate MAO enzyme, leading to accumulation of NE and 5-HT, which activates their receptors and exerts an antidepressant effect.

Mechanism of Action of MAOIs

Irreversible inhibitors of MAO enzyme.
Antidepressant action is delayed for several weeks (clinical improvement appears slowly > 2 weeks).
Effect persists for 2-3 weeks after stopping the drug, which is the time taken for regeneration of a new enzyme.