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Fungi Characteristics and Antifungal Agents
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Fungi Characteristics and Antifungal Agents

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@BonnyHappiness

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Questions and Answers

What is the sugar concentration in laboratory media suitable for fungi?

  • 5-6%
  • 3-4%
  • 1-2%
  • 4-5% (correct)
  • To which type of agents are fungi sensitive?

  • Antiviral agents
  • Antibacterial agents
  • Antifungal agents (correct)
  • Antiparasitic agents
  • What do fungal cell membranes consist of?

  • Phospholipids
  • Glycoproteins
  • Ergosterol (correct)
  • Cholesterol
  • Which drugs act on ergosterol in fungal cell membranes?

    <p>Amphotericin B and azole group</p> Signup and view all the answers

    What do all fungi require as a carbon source?

    <p>Organic carbon</p> Signup and view all the answers

    Which type of cell do fungi have?

    <p>Eukaryotic</p> Signup and view all the answers

    What is the optimum pH range for fungal growth?

    <p>3.8-5</p> Signup and view all the answers

    Why are fungi insensitive to penicillins?

    <p>Their cell walls do not consist of peptidoglycan</p> Signup and view all the answers

    What is chitin composed of?

    <p>N-acetylglucosamine</p> Signup and view all the answers

    Which component of the fungal cell wall is the target of some antifungal drugs?

    <p>B-glucan</p> Signup and view all the answers

    Study Notes

    Characteristics of Fungi

    • All fungi are saprophytes, requiring a preformed organic source of carbon for growth.
    • Fungi have a unique cell membrane composition, featuring ergosterol instead of cholesterol, which is the site of action for antifungal drugs like amphotericin B and azole group.

    Physiology of Fungi

    • Fungi are aerobic, requiring oxygen for their development.
    • All fungi are eukaryotic, having a true nucleus, unlike bacteria which are prokaryotic.
    • Fungi have an optimal pH range for growth between 3.8-5, and an optimal temperature range of 22-28°C.

    Cell Wall Structure

    • Fungal cell walls contain large amounts of chitin and cellulose, but do not contain peptidoglycan, making them insensitive to antibiotics like penicillins.
    • Chitin is a polysaccharide composed of long chains of N-acetylglucosamine.
    • The fungal cell wall also contains β-glucan, which is the site of action for some antifungal drugs.

    Nutritional Requirements

    • Fungi require a preformed organic source of carbon, often associated with decaying matter.
    • Sugars are concentrated in laboratory media at 4-5% (compared to 1.5% for bacteria).

    Antibiotic Sensitivity

    • Fungi are sensitive to antifungal agents only, and are not affected by antibiotics that target bacterial cell walls.

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    Description

    This quiz covers the characteristics of fungi, including their cell membrane composition, nutritional requirements, and sensitivity to antifungal agents. Learn about the unique features of fungi and how they differ from bacteria.

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