Fungal Infection Mechanisms

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Questions and Answers

Which of the following scenarios is least likely to result in a fungal infection in an immunocompetent individual?

  • Inhalation of fungal spores in a well-ventilated environment. (correct)
  • Traumatic implantation of fungal spores into deep tissue.
  • Direct contact with _Candida albicans_ during childbirth.
  • Exposure to _Malassezia furfur_ on sebum-rich skin areas.

What is the MOST common initial fungal exposure for humans, as described?

  • Ingestion of fungal toxins through contaminated food.
  • Inhalation of _Aspergillus_ spores.
  • Exposure to _Candida albicans_ during birth. (correct)
  • Contact with _Malassezia furfur_ on the skin.

Intact skin and mucous membranes serve as:

  • Conduits for systemic fungal dissemination.
  • Primary sites of fungal colonization.
  • Barriers against opportunistic fungal infections. (correct)
  • Nutrient sources for fungal growth.

What is the significance of sebaceous glands in relation to Malassezia furfur?

<p>Areas rich in sebaceous glands provide a favorable environment for <em>Malassezia furfur</em> colonization. (B)</p> Signup and view all the answers

In which situation are fungi MOST likely to establish an opportunistic infection in a human host?

<p>When the host's immune system is compromised or physical barriers are breached. (C)</p> Signup and view all the answers

Flashcards

Portals of Entry

Ways through which fungi enter the human body, like skin or mucous membranes.

C. albicans

A yeast fungus commonly encountered during birth, often from the vaginal canal.

Malassezia furfur

A fungus found on skin areas rich in sebaceous glands.

Immunocompetent Hosts

Individuals with normal immune systems, usually resistant to fungal diseases.

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Traumatic Implantation

When fungi gain access to tissues through physical injury.

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Study Notes

Fungal Infection Entry Mechanisms

  • Fungi access the body through various portals of entry.
  • A common initial exposure for humans is to the yeast Candida albicans during childbirth, encountered in the vaginal canal.
  • Malassezia furfur is frequently found in areas with abundant sebaceous glands (e.g., skin).
  • Generally, fungi do not cause disease in healthy individuals with strong immune systems, despite constant exposure.
  • Infection occurs when fungi breach barriers like unbroken skin and mucous membranes.
  • Fungi enter tissues through traumatic implantation or inhalation.

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