Fundamentals of Virology Quiz

Fundamentals of Virology

• Viruses are the smallest infectious agents and contain only one type of nucleic acid (DNA or RNA).

• A virion is a mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without an envelope.

• Each virus contains only one kind of nucleic acid (DNA or RNA), classified as single stranded, double linear, circular segmented, or non-segmented.

• Each nucleocapsid contains a nucleic acid core surrounded by a protein coat, the capsid, with capsid symmetry either helical, icosahedral, or complex.

• Some viruses have envelopes which can be from the host cell membrane, host nuclear membrane, or are "naked".

• Naked viruses are environmentally stable, while enveloped viruses are environmentally labile and modify cell membrane during replication; they are released by budding and occasionally, cell lysis.

• Viruses range in size from 20-300 nm, with pox viruses being the largest DNA viruses, paramyxoviruses being the largest RNA viruses, and parvoviruses being the smallest animal virus.

• Viruses are obligate intracellular parasites and require other cells to reproduce since they do not have their own metabolic machineries.

• The replication cycle of viruses includes absorption, penetration, uncoating, synthesis, assembly of virion, and release.

• Laboratory diagnosis of viral infections includes clinical symptoms, direct examination, serology, and cell culture selection for virus isolation and presumptive diagnosis.

• DNA viruses include adenoviridae, hepadnaviridae, herpesviridae, papovaviridae, parvoviridae, and poxvindae.

• RNA viruses include arenavirus, bunyavindae, caliciviridae, coronavindae, filoviridae, orthomyxoviridae, paramyxoviridae, picornaviridae, and reoviridae.Summary of Viruses and Associated Diseases

• Gastroenteritis affects infants and children aged 6 months to 2 years.

• Colorado Tick Fever is caused by Orbivirus.

• Retroviridae is a family of viruses that are slightly pleomorphic to spherical and have a size range of 80-100 nm.

• HTLV-1 is associated with Adult T-cell leukemia, Sezary 7 cell leukemia, and lymphoma.

• HTLV-2 is associated with Hairy Cell leukemia.

• HIV-1 has three stages: asymptomatic, AIDS-Related Complex, and Full Blown AIDS.

• HIV-2 causes immunodeficiency and is less pathogenic than HIV-1.

• Rhabdoviridae is a family of bullet-shaped viruses with a size range of 50-95 nm x 130-389 nm.

• Rabies virus causes Rabies.

• Togaviridae is a family of spherical viruses with a size range of 60-70 nm.

• Alphavirus (Group A Arbovirus) includes Eastern equine encephalitis, Western equine encephalitis, Venezuelan equine encephalitis.

• Rubivirus causes German Measles or Rubella.

Fundamentals of Virology

• Viruses are the smallest infectious agents and contain only one type of nucleic acid (DNA or RNA).

• A virion is a mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without an envelope.

• Each virus contains only one kind of nucleic acid (DNA or RNA), classified as single stranded, double linear, circular segmented, or non-segmented.

• Each nucleocapsid contains a nucleic acid core surrounded by a protein coat, the capsid, with capsid symmetry either helical, icosahedral, or complex.

• Some viruses have envelopes which can be from the host cell membrane, host nuclear membrane, or are "naked".

• Naked viruses are environmentally stable, while enveloped viruses are environmentally labile and modify cell membrane during replication; they are released by budding and occasionally, cell lysis.

• Viruses range in size from 20-300 nm, with pox viruses being the largest DNA viruses, paramyxoviruses being the largest RNA viruses, and parvoviruses being the smallest animal virus.

• Viruses are obligate intracellular parasites and require other cells to reproduce since they do not have their own metabolic machineries.

• The replication cycle of viruses includes absorption, penetration, uncoating, synthesis, assembly of virion, and release.

• Laboratory diagnosis of viral infections includes clinical symptoms, direct examination, serology, and cell culture selection for virus isolation and presumptive diagnosis.

• DNA viruses include adenoviridae, hepadnaviridae, herpesviridae, papovaviridae, parvoviridae, and poxvindae.

• RNA viruses include arenavirus, bunyavindae, caliciviridae, coronavindae, filoviridae, orthomyxoviridae, paramyxoviridae, picornaviridae, and reoviridae.Summary of Viruses and Associated Diseases

• Gastroenteritis affects infants and children aged 6 months to 2 years.

• Colorado Tick Fever is caused by Orbivirus.

• Retroviridae is a family of viruses that are slightly pleomorphic to spherical and have a size range of 80-100 nm.

• HTLV-1 is associated with Adult T-cell leukemia, Sezary 7 cell leukemia, and lymphoma.

• HTLV-2 is associated with Hairy Cell leukemia.

• HIV-1 has three stages: asymptomatic, AIDS-Related Complex, and Full Blown AIDS.

• HIV-2 causes immunodeficiency and is less pathogenic than HIV-1.

• Rhabdoviridae is a family of bullet-shaped viruses with a size range of 50-95 nm x 130-389 nm.

• Rabies virus causes Rabies.

• Togaviridae is a family of spherical viruses with a size range of 60-70 nm.

• Alphavirus (Group A Arbovirus) includes Eastern equine encephalitis, Western equine encephalitis, Venezuelan equine encephalitis.

• Rubivirus causes German Measles or Rubella.

Fundamentals of Virology

• Viruses are the smallest infectious agents and contain only one type of nucleic acid (DNA or RNA).

• A virion is a mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without an envelope.

• Each virus contains only one kind of nucleic acid (DNA or RNA), classified as single stranded, double linear, circular segmented, or non-segmented.

• Each nucleocapsid contains a nucleic acid core surrounded by a protein coat, the capsid, with capsid symmetry either helical, icosahedral, or complex.

• Some viruses have envelopes which can be from the host cell membrane, host nuclear membrane, or are "naked".

• Naked viruses are environmentally stable, while enveloped viruses are environmentally labile and modify cell membrane during replication; they are released by budding and occasionally, cell lysis.

• Viruses range in size from 20-300 nm, with pox viruses being the largest DNA viruses, paramyxoviruses being the largest RNA viruses, and parvoviruses being the smallest animal virus.

• Viruses are obligate intracellular parasites and require other cells to reproduce since they do not have their own metabolic machineries.

• The replication cycle of viruses includes absorption, penetration, uncoating, synthesis, assembly of virion, and release.

• Laboratory diagnosis of viral infections includes clinical symptoms, direct examination, serology, and cell culture selection for virus isolation and presumptive diagnosis.

• DNA viruses include adenoviridae, hepadnaviridae, herpesviridae, papovaviridae, parvoviridae, and poxvindae.

• RNA viruses include arenavirus, bunyavindae, caliciviridae, coronavindae, filoviridae, orthomyxoviridae, paramyxoviridae, picornaviridae, and reoviridae.Summary of Viruses and Associated Diseases

• Gastroenteritis affects infants and children aged 6 months to 2 years.

• Colorado Tick Fever is caused by Orbivirus.

• Retroviridae is a family of viruses that are slightly pleomorphic to spherical and have a size range of 80-100 nm.

• HTLV-1 is associated with Adult T-cell leukemia, Sezary 7 cell leukemia, and lymphoma.

• HTLV-2 is associated with Hairy Cell leukemia.

• HIV-1 has three stages: asymptomatic, AIDS-Related Complex, and Full Blown AIDS.

• HIV-2 causes immunodeficiency and is less pathogenic than HIV-1.

• Rhabdoviridae is a family of bullet-shaped viruses with a size range of 50-95 nm x 130-389 nm.

• Rabies virus causes Rabies.

• Togaviridae is a family of spherical viruses with a size range of 60-70 nm.

• Alphavirus (Group A Arbovirus) includes Eastern equine encephalitis, Western equine encephalitis, Venezuelan equine encephalitis.

• Rubivirus causes German Measles or Rubella.

Fundamentals of Virology

• Viruses are the smallest infectious agents and contain only one type of nucleic acid (DNA or RNA).

• A virion is a mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without an envelope.

• Each virus contains only one kind of nucleic acid (DNA or RNA), classified as single stranded, double linear, circular segmented, or non-segmented.

• Each nucleocapsid contains a nucleic acid core surrounded by a protein coat, the capsid, with capsid symmetry either helical, icosahedral, or complex.

• Some viruses have envelopes which can be from the host cell membrane, host nuclear membrane, or are "naked".

• Naked viruses are environmentally stable, while enveloped viruses are environmentally labile and modify cell membrane during replication; they are released by budding and occasionally, cell lysis.

• Viruses range in size from 20-300 nm, with pox viruses being the largest DNA viruses, paramyxoviruses being the largest RNA viruses, and parvoviruses being the smallest animal virus.

• Viruses are obligate intracellular parasites and require other cells to reproduce since they do not have their own metabolic machineries.

• The replication cycle of viruses includes absorption, penetration, uncoating, synthesis, assembly of virion, and release.

• Laboratory diagnosis of viral infections includes clinical symptoms, direct examination, serology, and cell culture selection for virus isolation and presumptive diagnosis.

• DNA viruses include adenoviridae, hepadnaviridae, herpesviridae, papovaviridae, parvoviridae, and poxvindae.

• RNA viruses include arenavirus, bunyavindae, caliciviridae, coronavindae, filoviridae, orthomyxoviridae, paramyxoviridae, picornaviridae, and reoviridae.Summary of Viruses and Associated Diseases

• Gastroenteritis affects infants and children aged 6 months to 2 years.

• Colorado Tick Fever is caused by Orbivirus.

• Retroviridae is a family of viruses that are slightly pleomorphic to spherical and have a size range of 80-100 nm.

• HTLV-1 is associated with Adult T-cell leukemia, Sezary 7 cell leukemia, and lymphoma.

• HTLV-2 is associated with Hairy Cell leukemia.

• HIV-1 has three stages: asymptomatic, AIDS-Related Complex, and Full Blown AIDS.

• HIV-2 causes immunodeficiency and is less pathogenic than HIV-1.

• Rhabdoviridae is a family of bullet-shaped viruses with a size range of 50-95 nm x 130-389 nm.

• Rabies virus causes Rabies.

• Togaviridae is a family of spherical viruses with a size range of 60-70 nm.

• Alphavirus (Group A Arbovirus) includes Eastern equine encephalitis, Western equine encephalitis, Venezuelan equine encephalitis.

• Rubivirus causes German Measles or Rubella.