Functions of the Skin and Microbiology

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Questions and Answers

Which of the following is NOT a function of the skin?

Immune function

Temperature regulation

Production of insulin (correct)

Protection against UV light

What is a common type of infection that affects the skin and soft tissue?

Cellulitis (correct)

Rheumatoid arthritis

Lupus

Fibromyalgia

Which guideline is focused on the management of diabetes-related foot infections?

WHO Recommendations for Foot Ulcers

CDC 2021 Foot Care Guidelines

IWGDF/IDSA Guidelines 2023 (correct)

FDA Guidelines on Wound Care

What is a primary goal of applying guidelines to clinical practice regarding skin infections?

To create therapeutic plans for patients Signup and view all the answers

Which of the following is an essential part of the skin's role in homeostasis?

Insensible fluid loss Signup and view all the answers

Which organism is not commonly found colonizing the skin?

Pseudomonas aeruginosa Signup and view all the answers

What should be the initial management for purulent infections of the skin?

Incision and drainage plus cultures Signup and view all the answers

Which immune response is present upon the introduction of a new pathogen?

Innate response Signup and view all the answers

In the situation of a patient with systemic signs of infection, what is the recommended initial antibiotic administration?

Parenteral antibiotics until improvement Signup and view all the answers

Which condition does NOT indicate severe infection in a patient?

Leukopenia with no symptoms Signup and view all the answers

What is dysbiosis in the context of skin infections?

Increase of pathogenic bacteria Signup and view all the answers

Which of the following indicates that cultures are not useful?

Non-purulent infections Signup and view all the answers

What is the function of the innate immune response in skin pathology?

To initiate immediate defense against pathogens Signup and view all the answers

Which layer of the skin contains hair follicles and exocrine glands?

Dermis Signup and view all the answers

What type of cells in the epidermis contribute to the immune system?

Keratinocytes Signup and view all the answers

Which of the following is a component of the subcutaneous layer of the skin?

Adipose tissue Signup and view all the answers

Which genus is NOT typically found in the skin microbiome?

Escherichia Signup and view all the answers

What factors influence the diversity of the skin microbiome?

Host physiology and lifestyle Signup and view all the answers

Which of these fungal genera is part of the skin microbiome?

Malassezia Signup and view all the answers

Which of the following roles do keratinocytes fulfill in the epidermis?

Provide structural integrity Signup and view all the answers

Which of the following options is NOT a characteristic of the dermis layer of skin?

Lacks nerve endings Signup and view all the answers

Study Notes

Functions of the Skin

The skin is a multifunctional organ with many roles
Temperature regulation
Homeostasis/insensible fluid loss
Protection against UV light
Physical barrier against trauma
Sensory perception
Immune function

Anatomy & Physiology

Epidermis (outer layer)
- Keratinocytes & Langerhans’ cells contribute to the immune system
- Skin microbiome
Dermis (middle layer)
- Connective tissue, hair follicles, exocrine glands, neurons & blood vessels
Subcutaneous/Hypodermis (inner layer)
- Adipose tissue, neurons & blood vessels

Microbiology

Skin microbiome
- Diverse communities of superficial, deep surface, and adherent microbes
- Dependent on host physiology, environment, immune system, and lifestyle
- Predominant bacterial genera at each skin site:
  - Staphylococcus spp.
  - Streptococcus spp.
  - Corynebacterium spp.
  - Eubacterium spp.
  - Propionibacterium spp.
  - Candida spp. (fungi)
  - Malassezia spp. (fungi)

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Description

Explore the multifunctional roles of the skin, including temperature regulation, protection, and sensory perception. This quiz also covers the skin's anatomy, including the epidermis, dermis, and subcutaneous layers, along with the diverse communities of the skin microbiome.