18 Questions
What is the molecular weight of IgD?
200,000
Which immunoglobulin is responsible for releasing histamine from basophils and mast cells?
IgE
Which immunoglobulin can serve as a B-cell receptor?
IgD
Which immunoglobulin is involved in opsonization?
IgG
Which immunoglobulin has 10 antigen-binding sites?
IgM
What is the percentage of total antibody in serum for IgE?
0.002%
What is the primary signal that a molecule is foreign?
Epitope
Which chemical category includes materials like enzymes, cell surface structures, hormones, and exotoxins?
Proteins and polypeptides
What are haptens made up of?
Determinant group only
In general, what characteristic makes large antigens considered better than small antigens?
Size
What role do glycoproteins play in the immune response?
They mark blood cell antigens
What must be done to a hapten for it to develop immunogenicity?
Link it to a carrier group
What is the main function of the Fab fragment of an immunoglobulin?
It binds antigens
Which of the following is NOT a function of the Fc fragment of an immunoglobulin?
Neutralizing antigens
What is the process where antibodies mark pathogens for destruction by phagocytic cells?
Opsonization
In blood transfusion or organ grafting, which molecules are responsible for incompatibilities between individuals?
Alloantigens
Which of the following is a characteristic of superantigens?
They can lead to a cytokine storm
Which cell type is responsible for formally presenting antigens to antigen-presenting cells (APCs)?
Macrophages
This quiz covers the functions of the Fc fragment of immunoglobulins, including opsonization, attachment to foreign cells, complement binding, cytokine release, and histamine release. It also discusses the varying amounts of carbohydrates attached to immunoglobulins.
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