Functions of Immunoglobulin Fc Fragment

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18 Questions

What is the molecular weight of IgD?

200,000

Which immunoglobulin is responsible for releasing histamine from basophils and mast cells?

IgE

Which immunoglobulin can serve as a B-cell receptor?

IgD

Which immunoglobulin is involved in opsonization?

IgG

Which immunoglobulin has 10 antigen-binding sites?

IgM

What is the percentage of total antibody in serum for IgE?

0.002%

What is the primary signal that a molecule is foreign?

Epitope

Which chemical category includes materials like enzymes, cell surface structures, hormones, and exotoxins?

Proteins and polypeptides

What are haptens made up of?

Determinant group only

In general, what characteristic makes large antigens considered better than small antigens?

Size

What role do glycoproteins play in the immune response?

They mark blood cell antigens

What must be done to a hapten for it to develop immunogenicity?

Link it to a carrier group

What is the main function of the Fab fragment of an immunoglobulin?

It binds antigens

Which of the following is NOT a function of the Fc fragment of an immunoglobulin?

Neutralizing antigens

What is the process where antibodies mark pathogens for destruction by phagocytic cells?

Opsonization

In blood transfusion or organ grafting, which molecules are responsible for incompatibilities between individuals?

Alloantigens

Which of the following is a characteristic of superantigens?

They can lead to a cytokine storm

Which cell type is responsible for formally presenting antigens to antigen-presenting cells (APCs)?

Macrophages

This quiz covers the functions of the Fc fragment of immunoglobulins, including opsonization, attachment to foreign cells, complement binding, cytokine release, and histamine release. It also discusses the varying amounts of carbohydrates attached to immunoglobulins.

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