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Functions and Characteristics of Bone

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Questions and Answers

What is the function of osteocytes in bone?

Maintenance of bone matrix (correct)

Resorption of bone

Release of calcium and phosphate

Production of bone matrix

Which type of cells give rise to osteoblasts?

Osteogenic cells (correct)

Hematopoietic cells

Osteoclasts

Osteocytes

What is the primary component of the inorganic matrix of bone?

Proteoglycans

Hydroxyapatite (correct)

Ground substance

Type I collagen fibers

Which hormone promotes bone formation?

Estrogen Signup and view all the answers

What is the primary function of osteoclasts?

Resorption of bone Signup and view all the answers

What is the function of Howship’s lacunae in relation to osteoclasts?

It is the site where osteoclasts lie and actively resorb bone Signup and view all the answers

What happens when serum calcium is low?

Parathyroid hormone is released, stimulating osteoclasts to resorb bone Signup and view all the answers

What characterizes mature (secondary, lamellar) bone at a microscopic level?

Arranged in osteons: layers (lamellae) of bone around little canals Signup and view all the answers

What is the main component of bone matrix in terms of dry weight?

Inorganic components, mostly calcium Signup and view all the answers

What is the process that occurs when osteoclasts actively resorb bone?

The osteoclast transfers collagenase and protons into an acidic microenvironment, breaking down collagen fibers and calcium salts Signup and view all the answers