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Functional Genomics and Epigenetics Overview Quiz

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Functional Genomics and Epigenetics Overview Quiz

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Questions and Answers

What is the primary purpose of DNA methylation at promoters and gene bodies?

Increase histone acetylation

Activate gene expression

Enhance alternative splicing

Repress gene expression (correct)

Which of the following is NOT a form of histone modification mentioned in the text?

Histone acetylation

Histone methylation

Histone phosphorylation (correct)

Histone ubiquitination

What are some factors that can cause DNA methylation changes according to the text?

Hormonal imbalances

Weather conditions

Social environment (correct)

Bacterial infections

How are epigenetic marks transmitted during cell division?

During mitosis to daughter cells Signup and view all the answers

What does a CpG island refer to in the context of DNA methylation?

Regions with high CpG density Signup and view all the answers

Which genes are mentioned to be linked to diseases affected by epigenetic changes?

'Pulmonary function' genes Signup and view all the answers

What is one of the long-term effects of early environmental exposures according to the text?

Induction of stable epigenetic changes Signup and view all the answers

What is the primary focus of Epigenome-wide association studies (EWAS)?

Analyzing DNA methylation at thousands of sites in the genome Signup and view all the answers

What is the main consequence of low expression of the glucocorticoid receptor in rats?

Higher anxiety and aggression Signup and view all the answers

What role does DNA methylation play in the regulation of gene expression?

Silences gene activity Signup and view all the answers

How do changes in DNA methylation patterns affect behavior in rats according to the text?

Lead to higher anxiety and aggression Signup and view all the answers

What distinguishes Epigenome-wide association studies (EWAS) from Genome-wide association studies (GWAS)?

Measure epigenetic marks related to traits or diseases Signup and view all the answers