Functional Genomics and Epigenetics Overview Quiz
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Questions and Answers

What is the primary purpose of DNA methylation at promoters and gene bodies?

  • Increase histone acetylation
  • Activate gene expression
  • Enhance alternative splicing
  • Repress gene expression (correct)

Which of the following is NOT a form of histone modification mentioned in the text?

  • Histone acetylation
  • Histone methylation
  • Histone phosphorylation (correct)
  • Histone ubiquitination

What are some factors that can cause DNA methylation changes according to the text?

  • Hormonal imbalances
  • Weather conditions
  • Social environment (correct)
  • Bacterial infections

How are epigenetic marks transmitted during cell division?

<p>During mitosis to daughter cells (A)</p> Signup and view all the answers

What does a CpG island refer to in the context of DNA methylation?

<p>Regions with high CpG density (D)</p> Signup and view all the answers

Which genes are mentioned to be linked to diseases affected by epigenetic changes?

<p>'Pulmonary function' genes (D)</p> Signup and view all the answers

What is one of the long-term effects of early environmental exposures according to the text?

<p>Induction of stable epigenetic changes (A)</p> Signup and view all the answers

What is the primary focus of Epigenome-wide association studies (EWAS)?

<p>Analyzing DNA methylation at thousands of sites in the genome (C)</p> Signup and view all the answers

What is the main consequence of low expression of the glucocorticoid receptor in rats?

<p>Higher anxiety and aggression (C)</p> Signup and view all the answers

What role does DNA methylation play in the regulation of gene expression?

<p>Silences gene activity (C)</p> Signup and view all the answers

How do changes in DNA methylation patterns affect behavior in rats according to the text?

<p>Lead to higher anxiety and aggression (C)</p> Signup and view all the answers

What distinguishes Epigenome-wide association studies (EWAS) from Genome-wide association studies (GWAS)?

<p>Measure epigenetic marks related to traits or diseases (A)</p> Signup and view all the answers

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