Fuel Sources for the Normal Heart and Ketone Bodies as Energy Source

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10 Questions

Which of the following is NOT a function of Carnitine Acyl Transferase I (CAT-I) in cardiac muscle?

Regenerating acyl-CoA from acyl-carnitine in the mitochondrial matrix

Which of the following is TRUE regarding the fate of long-chain fatty acyl-CoA in cardiac muscle?

It can be converted to acyl-carnitine by CAT-I and transported into mitochondria

Which of the following statements is correct regarding the energy yield from the complete oxidation of a C16 fatty acid (palmitate) in cardiac muscle?

It generates 8 acetyl-CoA molecules, which produce 129 ATP through the TCA cycle and electron transport chain

Which of the following statements is TRUE regarding the regulation of fatty acid oxidation in cardiac muscle?

Increased plasma free fatty acid levels promote fatty acid oxidation

Which of the following is a product of fatty acid beta-oxidation in cardiac muscle mitochondria?

NADH and FADH2

What is the primary role of carnitine in cardiac muscle fatty acid metabolism?

To facilitate the transport of long-chain acyl-CoA into the mitochondrial matrix

Which of the following statements is TRUE regarding the regulation of fatty acid oxidation in cardiac muscle during fasting or exercise?

Fatty acid oxidation is increased to meet the energy demands

Which of the following statements is correct regarding the entry of free fatty acids (FFAs) into cardiac muscle cells?

FFAs can enter cardiomyocytes through both passive diffusion and protein-mediated transport

Which of the following is NOT a product of fatty acid beta-oxidation in cardiac muscle mitochondria?

Oxaloacetate

Which of the following statements is correct regarding the intracellular pool of triglycerides in cardiac muscle?

It constitutes 10-30% of the fatty acids taken up by cardiomyocytes

Explore the fuels that the normal heart utilizes including ATP, acetyl CoA, and free fatty acids. Learn about the utilization of ketone bodies as an energy source for cardiac muscles in conditions like starvation and uncontrolled diabetes. Test your knowledge on cardiac muscle energy sources!

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