Fructose Metabolism and Liver Health Quiz

Fructose Metabolism

• The major rate-limiting step in glycolysis that fructose bypasses is phosphofructokinase-1.

Liver Steatosis

• The potential cause of liver steatosis due to fructose metabolism is the uncontrolled generation of acetyl-CoA, which can lead to excessive fat synthesis.

Fat Synthesis

• Acetyl-CoA is a precursor to fat synthesis.

Uncontrolled Fructose Metabolism

• The consequence of fructose being metabolized without any control to acetyl-CoA is the unregulated production of fat, leading to liver steatosis and other metabolic disorders.

Fructokinase Deficiency

• Fructokinase deficiency, also known as essential fructosuria, results in the inability to metabolize fructose, leading to its excretion in the urine.

Fructose Metabolism Pathway

• Fructose is directly cleaved without going through the phosphofructokinase-1 step, causing the metabolization of acetyl-CoA without any control.

Liver Condition

• The term for the condition where there is an accumulation of fat in the liver is liver steatosis.

Fructokinase Enzyme

• The term for the enzyme that converts fructose to fructose 1 phosphate is fructokinase.