Free Triiodothyronine (FT3) and Thyroglobulin: Clinical Utility and Interpretation
21 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the reference range for Thyroxine (T4) levels?

  • 0.9–1.7 ng/dL
  • 80–200 ng/dL
  • 2.5–5.0 mIU/L
  • 0.4–4.0 mIU/L (correct)

    • What percentage of Triiodothyronine (T3) is derived from the deiodination of T4?

  • 20%
  • 40%
  • 60%
  • 80% (correct)

    • What is the reference range for Free Thyroxine (FT4) levels?

  • 0.4–4.0 mIU/L
  • 0.9–1.7 ng/dL (correct)
  • 80–200 ng/dL
  • 2.5–5.0 mIU/L

    • Which of the following is the biologically active fraction of T4?

    <p>Free T4 (FT4)</p> Signup and view all the answers

    Which of the following can interfere with the measurement of Free Thyroxine (FT4) levels?

    <p>Both thyroid autoantibodies/biotin and HAMA</p> Signup and view all the answers

    What is the ideal use of Thyroglobulin as a diagnostic test?

    <p>Detecting thyroid cancer recurrence post-surgery</p> Signup and view all the answers

    Which assay is used to detect Thyroglobulin, ensuring its detection even when undetectable?

    <p>Immunochemiluminescent assay (ICMA)</p> Signup and view all the answers

    What is the main cause of hyperthyroidism in Graves’ disease?

    <p>Antibodies directed at the TSH receptor</p> Signup and view all the answers

    Which test is primarily used for diagnosing Hashimoto’s thyroiditis?

    <p>Thyroglobulin Antibody test</p> Signup and view all the answers

    How are antibodies against thyroglobulin (Tg) produced?

    <p>Through autoimmune hypothyroidism</p> Signup and view all the answers

    What diagnostic tool is used to confirm hyperthyroidism in patients with an altered distribution of thyroid binding proteins?

    <p>Free Triiodothyronine (FT3) test</p> Signup and view all the answers

    Which gland is responsible for the production of thyroid hormone and calcitonin?

    <p>Thyroid gland</p> Signup and view all the answers

    What is the anatomical position of the thyroid gland?

    <p>Lower anterior neck</p> Signup and view all the answers

    Which of the following is rich in the amino acid tyrosine and is a major component of colloid in the thyroid follicles?

    <p>Thyroglobulin</p> Signup and view all the answers

    What is the main function of Type 1 iodothyronine 5'-deiodinase?

    <p>Most abundant form, contributes to the circulating T3 pool</p> Signup and view all the answers

    Which enzyme catalyzes the oxidation and binding of iodide with tyrosyl residues on thyroglobulin in the thyroid follicles?

    <p>Thyroid peroxidase (TPO)</p> Signup and view all the answers

    What is the precursor with minimal hormonal effect and stored in the thyroid lumen filled with colloid?

    <p>Thyroglobulin</p> Signup and view all the answers

    Which hormone is released from the anterior pituitary to signal the follicular cell to ingest a droplet of colloid by endocytosis?

    <p>Thyroid-stimulating hormone (TSH)</p> Signup and view all the answers

    What hormone is considered a prohormone precursor with minimal hormonal effect?

    <p>Thyroglobulin</p> Signup and view all the answers

    What is the main function of Type 2 iodothyronine 5'-deiodinase?

    <p>Maintains constant levels of T3 in the central nervous system</p> Signup and view all the answers

    What are the effects of Thyroid Hormone on Tissue growth, Brain maturation, Energy production, and Oxygen consumption primarily due to?

    <p>Increased expression of β-adrenergic receptors</p> Signup and view all the answers

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser