Foreign Body Granulomas Quiz
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Questions and Answers

Which enzyme contributes to the destruction of engulfed antigens by generating hypochlorite and hydroxyl radical inside the phagosome?

  • Lactoferrin
  • Lysozyme
  • Myeloperoxidase (correct)
  • Collagenase
  • Which of the following is NOT a toxic oxygen species involved in the destruction of engulfed antigens?

  • Lactoferrin (correct)
  • Nitric Oxide
  • Hydroxyl Radical
  • Reactive Oxygen Intermediates
  • What contributes to oxygen-independent destruction of antigens by creating low intravacuolar pH?

  • Collagenase
  • Carbonic Acid (correct)
  • Lactoferrin
  • Lysozyme
  • Which enzyme, released in degranulation, causes tissue injury by proteolysis?

    <p>Elastase</p> Signup and view all the answers

    What is the term used to describe the inflammation of lymphatic vessels?

    <p>Lymphangitis</p> Signup and view all the answers

    What can cause lymph nodes to enlarge in the context of inflammation?

    <p>Hyperplasia of lymphoid follicles</p> Signup and view all the answers

    Which resistance factor contributes to chronic inflammation by preventing phagocytosis?

    <p>Resistance of infective agent to phagocytosis</p> Signup and view all the answers

    Which autoimmune disease is an example of non-organ-specific autoimmune disease according to the text?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    What type of immune response incites foreign body granulomas?

    <p>B cell-mediated immune response</p> Signup and view all the answers

    Which cells are typically found apposed to the surface of a foreign body in a granuloma?

    <p>Epithelioid cells and giant cells</p> Signup and view all the answers

    What causes central necrosis in granulomatous inflammation?

    <p>Combination of hypoxia and free radical–mediated injury</p> Signup and view all the answers

    Which type of immune response is associated with granulomatous inflammation due to parasitic infections like schistosomiasis?

    <p>Th1 responses with IFNγ production</p> Signup and view all the answers

    What is the role of arachidonic acid metabolites in inflammation?

    <p>Mediate leukocyte chemotaxis and vascular reactions</p> Signup and view all the answers

    Which proteins mainly mediate leukocyte recruitment and migration in acute inflammation?

    <p>Cytokines</p> Signup and view all the answers

    What effect do vasoactive amines, mainly histamine, have on blood vessels during inflammation?

    <p>Cause vasodilation and increased vascular permeability</p> Signup and view all the answers

    Which cell-produced proteins act at short range and mediate multiple effects in acute inflammation?

    <p>Chemokines</p> Signup and view all the answers

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