system biology

What is the main focus of Systems Biology?

What is the main difference between Genetics and Genomics?

What is the analogy used to describe the replacement of molecules in a cell over time?

According to the text, what is the definition of a system?

What is the study of systems biology mainly focused on?

What is emergence in the context of systems biology?

Why is systems biology important in understanding diseases?

Which of the following is a typical timescale for the transcription and translation of a gene in E. coli?

What is the purpose of mathematical modeling in biology?

Which of the following is true about biological networks?

What is the purpose of community standard data models in omics data and modeling?

What is a model in the context of mathematical modeling?

Which of the following characteristics are important for model organisms?

What is one advantage of computational modeling in biology?

What is the purpose of modeling in systems biology?

Which type of model describes the components and their relations using a graph representation?

Which of the following is a common approach used in mathematical modeling of biochemical systems?

What is a system state in a computational model?

What is the purpose of creating a mathematical model of a biological system?

What is the purpose of constructing models in such a way that disregarded properties do not compromise the basic results?

What is the most frequently used approach to model the static and dynamic behaviors of biochemical networks?

What is the difference between a variable and a parameter in a model?

What is the purpose of the iterative modeling cycle mentioned in the text?

Which state function relates enthalpy (H), entropy (S), and temperature (T)?

Systems Biology is the study of _______ in biological systems.

Systems Biology focuses on _______ study on many genes/proteins.

Mathematical modeling is a process of creating and refining a ______.

Simulation is the manipulation of a ______ in such a way that it operates on time or space to predict how the system works.

A ______ represents specific aspects of reality and is sufficient to answer particular questions.

Modeling highlights ______ in knowledge or understanding.

Models are never 'right,' but can be _______ and helpful.

A model contains various kinds of statements and equations describing facts about the model _______.

The quantities in a model can be classified as variables, ________, and constants.

A biological process can be described with different (mathematical) models. The choice of a mathematical model or an algorithm to describe a biological object depends on the problem, the purpose, and the ________ of the investigator.

Systems biology views biology as dynamic networks of interactions. A system is any collection of interacting parts with ______ behavior.

The interconnections of biological components of cells are taking center stage in ______.

Systems biology is the study of the interactions between the components of biological systems, and how these interactions give rise to the function and behavior of that ______.

Biological processes are the result of complex and dynamic interactions within and between cells, organs, and entire ______.

Biological networks are best represented by ______ that consist of nodes and edges.

Common schemes for data storage, data representation, and data transfer in omics data include ______.

Model organisms are organisms that are well-studied, fit for laboratory study, have a short life cycle, are small and easy to maintain, and have rapid and reliable growth in a laboratory. They also have the existence of excellent ______.

Modeling is an abstraction of reality and is not the reality itself. Model organisms can be used to study a simple organism rather than a complex one, as long as the basic biology is ______.

Mathematical modeling is necessary in biology because it is difficult to intuitively figure out how the concentrations of different species behave over time. We need support by mathematical modeling and software tools to ______ that.

One major function of models is to make assumptions about the underlying process explicit and, hence, ______.

Three major types of computational/mathematical models used in biological systems are network-based models, rule-based models, and ______.

The most frequently used approach to model the static and dynamic behaviors of biochemical networks is through systems of ordinary differential equations (ODE). This formulation allows us to assign kinetic laws to all reactions and determine the values of the ______.

Chemical reactions in a cell are accompanied by changes in ________.

Gibbs free energy (G) is a state function that relates ________, entropy (S), and temperature (T).

Activation energy is the energy required to bring all molecules in a chemical reaction into the ________ state.