FMGE Dec 2017: Selective Estrogen Receptor Modulator
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Questions and Answers

Which of the following is a selective estrogen receptor modulator?

  • Fulvestrant
  • Flutamide
  • Clomiphene citrate
  • Tamoxifen (correct)
  • Which type of stone is insensitive to alkaline pH of urine?

  • Xanthine stones (correct)
  • Cysteine stones
  • Struvite stones
  • Calcium stones
  • Which of the following drugs is a selective antagonist of androgen receptor?

  • Clomiphene citrate
  • Flutamide (correct)
  • Tamoxifen
  • Fulvestrant
  • What is the main cause of struvite stones formation?

    <p>Alkaline urine</p> Signup and view all the answers

    Which type of stone is caused by a deficiency of xanthine oxidase?

    <p>Xanthine stones</p> Signup and view all the answers

    Study Notes

    Selective Estrogen Receptor Modulators (SERMs)

    • Specific SERMs were not listed, requiring further information to provide an answer. A list of potential candidates would enable a definitive response.

    Urinary Stones and pH Sensitivity

    • The question lacks specifics on the types of urinary stones presented, rendering a precise answer impossible. Different stone compositions have varying pH sensitivities.

    Selective Androgen Receptor Antagonists

    • Similar to the SERM question, no specific drugs were provided. A list of potential drugs is needed for accurate identification.

    Struvite Stone Formation

    • The primary cause of struvite stones is infection with urease-producing bacteria. Urease hydrolyzes urea, leading to an alkaline urine pH which promotes struvite precipitation.

    Xanthine Oxidase Deficiency and Stones

    • Xanthine oxidase deficiency causes uric acid stones, or more accurately, xanthine stones which are less common. This is because xanthine oxidase is involved in the metabolism of purines to uric acid, a deficiency results in xanthine accumulation leading to xanthine stone formation.

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    Description

    Test your knowledge of medical concepts with this FMGE recall quiz from December 2017. Can you identify the selective estrogen receptor modulator from the given options and explain its mechanism of action?

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