Flutamide (Eulexin) Flashcards

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Questions and Answers

What is the therapeutic class of Flutamide (Eulexin)?

  • Antineoplastic (correct)
  • Analgesic
  • Antibiotic
  • Antidepressant

What is the pharmacologic class of Flutamide (Eulexin)?

  • Cytotoxic Agent
  • Hormonal Therapy
  • Steroidal Antiandrogen
  • Nonsteroidal Antiandrogen (correct)

What action does Flutamide (Eulexin) perform?

Inhibits androgen uptake or prevents binding of androgens in nucleus of cells in target tissues

Flutamide (Eulexin) is indicated for __________.

<p>Prostate Cancer</p>
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Which of the following are side effects of Flutamide (Eulexin)? (Select all that apply)

<p>Liver Failure (B), Erectile dysfunction (C), Nausea (D)</p>
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What may prolong PT/INR when taking Flutamide (Eulexin)?

<p>Warfarin</p>
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What are some nursing implications for Flutamide (Eulexin)?

<p>Monitor liver function tests and CBC, must be taken continuously with drugs like leuprolide.</p>
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Patients should take Flutamide (Eulexin) with a full glass of __________.

<p>water</p>
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What is the route of administration for Flutamide (Eulexin)?

<p>PO (C)</p>
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Study Notes

Flutamide (Eulexin) Overview

  • Classifies as an antineoplastic medication aimed at cancer treatment.
  • Belongs to the nonsteroidal antiandrogen pharmacologic class, targeting androgen actions in the body.

Mechanism of Action

  • Functions by inhibiting the uptake of androgens and blocking their binding in target tissue cell nuclei, reducing androgenic effects.

Side Effects

  • Common adverse effects include leukopenia, hot flashes, nausea, vomiting, thrombocytopenia, and erectile dysfunction.
  • Potential severe side effects consist of liver failure, urine discoloration, diminished libido, and cystitis.

Indications

  • Primarily indicated for the treatment of prostate cancer, serving as part of a comprehensive therapy plan.

Drug Interactions

  • Notably interacts with warfarin, which may lead to prolonged PT/INR, requiring careful monitoring.

Nursing Considerations

  • Liver function tests are crucial before initiating treatment due to the drug's potential for causing liver failure.
  • Continuous monitoring of CBC is advised.
  • Should be taken alongside medications like leuprolide for optimal therapeutic efficacy.

Patient Education

  • Instruct patients to take Flutamide with a full glass of water and possibly with food to mitigate stomach irritation.
  • Educate on reporting adverse reactions, particularly concerning discolored urine, persistent vomiting, or any yellowing of the skin or eyes.

Administration

  • Administered orally (PO) for ease of use and patient compliance.

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