28 Questions
Which type of antidepressants are most commonly used to treat somatic symptom illnesses?
Selective serotonin reuptake inhibitors
What is the usual dose range for fluoxetine (Prozac) when used to treat somatic symptom illnesses?
20–60 mg/day
What is a potential nursing consideration for sertraline (Zoloft) when used to treat somatic symptom illnesses?
Monitor for diarrhea and sexual dysfunction
What is recommended for clients with pain disorder to help improve functional abilities?
Referral to a chronic pain clinic
What is the primary focus of cognitive-behavioral group therapy for clients with somatic symptom disorder and illness anxiety disorder?
Improvement in physical and emotional health
Which disorder tends to remit in a few weeks but recur in 25% of cases?
Conversion disorder
What is the primary reason for caution in older adults when using SSRIs like fluoxetine?
Slower elimination
What is a notable adverse effect of fluoxetine in patients with hepatic impairment?
Higher plasma levels
Which condition is fluoxetine effective in treating, according to the text?
Premenstrual dysphoric disorder
What is the primary concern regarding the use of fluoxetine in children, adolescents, and young adults?
Increased risk of suicidal ideation
What is the potential consequence of abrupt termination of SSRIs like fluoxetine?
Antidepressant discontinuation syndrome
What is a notable effect of fluoxetine's long half-life?
Slow accumulation
What is a potential risk of concurrent use of fluoxetine and MAO inhibitors?
Serotonin syndrome
What is a reason for the preference of SSRIs, including fluoxetine, in older adults?
Fewer adverse effects
What is a notable adverse effect of fluoxetine, as mentioned in the text?
Sexual dysfunction
What type of therapy was effective for somatic illness or symptoms, according to the text?
Education and information through internet-based material and books
What is a contraindication for fluoxetine use?
Known sensitivity to the drug
How often do patients typically take fluoxetine?
Once daily in the morning with food
What is a potential adverse effect of fluoxetine?
Nausea
What is the therapeutic serum level range for fluoxetine?
100 to 800 ng/mL
What enzyme system may fluoxetine affect, leading to drug interactions?
CYP2D6
What is the recommended timeframe for the full therapeutic effects of fluoxetine to be seen?
8 to 12 weeks
Which class of drugs does fluoxetine belong to?
Selective serotonin reuptake inhibitors (SSRIs)
What is a potential consequence of taking fluoxetine concurrently with codeine?
Lack of pain relief
What should patients be cautious of when taking fluoxetine and other medications?
Potential drug interactions
Who should not receive fluoxetine?
People who have attempted suicide
Which of the following drugs is NOT in the same class as fluoxetine?
Thioridazine
What should patient teaching guidelines emphasize for antidepressants like fluoxetine?
The importance of taking the medication as directed
Study Notes
Fluoxetine and its characteristics
- Fluoxetine has a long half-life and is not associated with withdrawal symptoms.
- Contraindications include known sensitivity to the drug, use of MAO inhibitors, and thioridazine.
- People who have attempted suicide should not receive fluoxetine.
- Fluoxetine competes with endogenous compounds and other medications for binding sites, leading to potential drug interactions.
- The drug may cause accumulation of other drugs using the CYP2D6 enzyme system.
- Fluoxetine can prevent the conversion of codeine to its active form, resulting in lack of pain relief when used concurrently.
- Patients typically take fluoxetine once daily in the morning with food to avoid GI upset.
- Therapeutic effects of fluoxetine may take 8 to 12 weeks to be fully seen.
- Therapeutic serum levels of fluoxetine range from 100 to 800 ng/mL.
- Adverse effects of fluoxetine include dizziness, headache, insomnia, nausea, and sexual dysfunction.
- Patient teaching guidelines for antidepressants emphasize the importance of taking the medication as directed and not altering doses without consulting a health care provider.
- Other drugs in the same class as fluoxetine include citalopram, escitalopram, paroxetine, sertraline, and vilazodone, each with its own characteristics and precautions.
Test your knowledge of fluoxetine with this quiz. Explore its characteristics, contraindications, drug interactions, therapeutic effects, and patient teaching guidelines. Learn about its potential adverse effects and related drugs in the same class.
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