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Questions and Answers
What is the approximate volume of interstitial fluid in a 70-kg man?
What is the approximate volume of interstitial fluid in a 70-kg man?
Which of the following is NOT a major constituent of the extracellular fluid?
Which of the following is NOT a major constituent of the extracellular fluid?
What is the primary reason for the difference in composition between plasma and interstitial fluid?
What is the primary reason for the difference in composition between plasma and interstitial fluid?
What is the approximate percentage of body weight that is made up of extracellular fluid?
What is the approximate percentage of body weight that is made up of extracellular fluid?
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What is the main difference between blood and other extracellular fluid compartments?
What is the main difference between blood and other extracellular fluid compartments?
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What is the approximate volume of plasma in a 70-kg man?
What is the approximate volume of plasma in a 70-kg man?
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Which of the following is the largest extracellular fluid compartment?
Which of the following is the largest extracellular fluid compartment?
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What is the primary mechanism by which the body regulates water intake and output, as well as electrolyte balance?
What is the primary mechanism by which the body regulates water intake and output, as well as electrolyte balance?
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What is the term used to describe the water loss that occurs through the skin and lungs, which is not easily perceived?
What is the term used to describe the water loss that occurs through the skin and lungs, which is not easily perceived?
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What is the primary mechanism for exchange of substances between plasma and interstitial fluid?
What is the primary mechanism for exchange of substances between plasma and interstitial fluid?
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How much water is typically lost through the kidneys each day under normal conditions?
How much water is typically lost through the kidneys each day under normal conditions?
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What is the primary source of water intake for the body?
What is the primary source of water intake for the body?
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How does heavy exercise affect the amount of water lost through perspiration?
How does heavy exercise affect the amount of water lost through perspiration?
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What is the approximate daily intake of water under normal conditions?
What is the approximate daily intake of water under normal conditions?
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According to table 25-1 what are the approximate daily water intake and output for a person engaging in heavy exercise?
According to table 25-1 what are the approximate daily water intake and output for a person engaging in heavy exercise?
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Which of the following is NOT a mechanism by which the body controls the rate of urine excretion?
Which of the following is NOT a mechanism by which the body controls the rate of urine excretion?
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What is the approximate average blood volume of an adult in liters?
What is the approximate average blood volume of an adult in liters?
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What percentage of blood is composed of plasma?
What percentage of blood is composed of plasma?
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What is the hematocrit?
What is the hematocrit?
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Why is the true hematocrit only about 96% of the measured hematocrit?
Why is the true hematocrit only about 96% of the measured hematocrit?
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What is the normal measured hematocrit for men?
What is the normal measured hematocrit for men?
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What is the condition called when the hematocrit is abnormally low, and what does it mean?
What is the condition called when the hematocrit is abnormally low, and what does it mean?
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What is the approximate percentage of red blood cells in blood?
What is the approximate percentage of red blood cells in blood?
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What is the primary reason for the slight difference in osmolarity between plasma and interstitial fluid?
What is the primary reason for the slight difference in osmolarity between plasma and interstitial fluid?
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What is the primary mechanism by which water moves across cell membranes?
What is the primary mechanism by which water moves across cell membranes?
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When a cell is placed in a solution that causes it to neither shrink nor swell, the solution is considered:
When a cell is placed in a solution that causes it to neither shrink nor swell, the solution is considered:
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The text mentions that interionic attraction can cause a slight decrease in the osmotic activity of dissolved substances. Which of the following best describes this phenomenon?
The text mentions that interionic attraction can cause a slight decrease in the osmotic activity of dissolved substances. Which of the following best describes this phenomenon?
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Why are 0.9% sodium chloride and 5% glucose solutions important in clinical medicine?
Why are 0.9% sodium chloride and 5% glucose solutions important in clinical medicine?
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Why is the pressure in capillaries slightly higher than in the surrounding interstitial spaces?
Why is the pressure in capillaries slightly higher than in the surrounding interstitial spaces?
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What is the primary function of the cell membrane in terms of water movement?
What is the primary function of the cell membrane in terms of water movement?
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What is the primary reason why water diffuses across the cell membrane towards a region of higher solute concentration?
What is the primary reason why water diffuses across the cell membrane towards a region of higher solute concentration?
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Which of the following ions has the highest concentration in the intracellular fluid?
Which of the following ions has the highest concentration in the intracellular fluid?
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Which of the following substances has a higher concentration in the extracellular fluid compared to the intracellular fluid?
Which of the following substances has a higher concentration in the extracellular fluid compared to the intracellular fluid?
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Which of the following statements about the ionic composition of plasma and interstitial fluid is TRUE?
Which of the following statements about the ionic composition of plasma and interstitial fluid is TRUE?
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What is the approximate concentration of potassium (K+) in interstitial fluid, according to the table?
What is the approximate concentration of potassium (K+) in interstitial fluid, according to the table?
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Which of the following ions is NOT found in intracellular fluid, based on the table?
Which of the following ions is NOT found in intracellular fluid, based on the table?
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What is the approximate concentration of bicarbonate (HCO3-) ions in plasma?
What is the approximate concentration of bicarbonate (HCO3-) ions in plasma?
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What is the indicator-dilution method primarily used for?
What is the indicator-dilution method primarily used for?
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According to the information provided, what is a key difference between extracellular fluid and intracellular fluid in terms of their ionic composition?
According to the information provided, what is a key difference between extracellular fluid and intracellular fluid in terms of their ionic composition?
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Which of the following statements accurately reflects the relationship between cell membranes and ion permeability?
Which of the following statements accurately reflects the relationship between cell membranes and ion permeability?
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What is the primary reason for the rapid movement of water across cell membranes?
What is the primary reason for the rapid movement of water across cell membranes?
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Why is the calculation of osmolarity using van't Hoff's law considered an approximation?
Why is the calculation of osmolarity using van't Hoff's law considered an approximation?
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What is the osmotic coefficient used for in the context of osmolarity calculations?
What is the osmotic coefficient used for in the context of osmolarity calculations?
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Which of the following factors primarily contributes to the osmolarity of interstitial fluid and plasma?
Which of the following factors primarily contributes to the osmolarity of interstitial fluid and plasma?
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What is the approximate osmolarity of a 0.9% sodium chloride solution, taking into account the osmotic coefficient?
What is the approximate osmolarity of a 0.9% sodium chloride solution, taking into account the osmotic coefficient?
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What is the main reason why the intracellular fluid remains isotonic with the extracellular fluid?
What is the main reason why the intracellular fluid remains isotonic with the extracellular fluid?
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Which statement best describes the role of osmotic pressure in volume regulation?
Which statement best describes the role of osmotic pressure in volume regulation?
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Flashcards
Extracellular Fluid (ECF)
Extracellular Fluid (ECF)
Fluid outside cells, includes interstitial fluid and plasma.
Interstitial Fluid
Interstitial Fluid
Fluid that fills spaces between cells, making up most of ECF.
Plasma
Plasma
Liquid component of blood that carries cells and nutrients, about 3 liters in a 70-kg man.
Body Weight Contribution
Body Weight Contribution
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Cation Concentrations
Cation Concentrations
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Anion Concentrations
Anion Concentrations
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Fluid Exchange
Fluid Exchange
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Blood as a Fluid Compartment
Blood as a Fluid Compartment
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Insensible water loss
Insensible water loss
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Daily water output
Daily water output
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Kidneys' role
Kidneys' role
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Urine excretion
Urine excretion
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Water intake balance
Water intake balance
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Normal water intake
Normal water intake
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Electrolyte balance
Electrolyte balance
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Insensible loss: skin vs lungs
Insensible loss: skin vs lungs
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Blood Volume
Blood Volume
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Plasma Composition
Plasma Composition
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Hematocrit
Hematocrit
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Normal Hematocrit Levels
Normal Hematocrit Levels
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Anemia Hematocrit
Anemia Hematocrit
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Polycythemia
Polycythemia
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Centrifuge Role
Centrifuge Role
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Plasma Non-Electrolytes
Plasma Non-Electrolytes
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Osmolarity of Plasma
Osmolarity of Plasma
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Na+ Concentration in Plasma
Na+ Concentration in Plasma
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K+ Concentration in Intracellular Fluid
K+ Concentration in Intracellular Fluid
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Anion Comparison
Anion Comparison
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HCO3− Concentration
HCO3− Concentration
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Calcium Ion in Plasma
Calcium Ion in Plasma
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Phosphates in Intracellular Fluid
Phosphates in Intracellular Fluid
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Indicator Mass Equation
Indicator Mass Equation
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Selective Permeability
Selective Permeability
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Osmolarity of Body Fluids
Osmolarity of Body Fluids
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Osmotic Pressure
Osmotic Pressure
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Isotonic Solution
Isotonic Solution
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Sodium Chloride Solution
Sodium Chloride Solution
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Plasma Proteins' Role
Plasma Proteins' Role
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Interstitial vs Intracellular Fluid
Interstitial vs Intracellular Fluid
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Corrected Osmolar Activity
Corrected Osmolar Activity
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Osmotic Coefficient
Osmotic Coefficient
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Sodium Chloride Osmolarity
Sodium Chloride Osmolarity
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Osmolarity Factors
Osmolarity Factors
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Intracellular Fluid Osmolarity
Intracellular Fluid Osmolarity
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Interstitial Fluid Osmolarity
Interstitial Fluid Osmolarity
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Permeability of Cell Membranes
Permeability of Cell Membranes
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Interionic Attraction
Interionic Attraction
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Study Notes
Regulation of Body Fluid Compartments
- Maintaining a stable body fluid volume and composition is crucial for homeostasis.
- Fluid balance is essential for cellular function.
- Daily fluid intake and output must be balanced for homeostasis.
Daily Water Intake
- Water intake comes from liquids and food (approx. 2100 ml/day).
- Water is also produced metabolically (approx. 200 ml/day).
- Total daily water intake is approximately 2300 ml.
- Water intake varies based on factors including climate, habits, and activity level.
Daily Water Loss
- Insensible Water Loss: Water lost through skin (300-400 ml/day) and respiration (300-400 ml/day).
- This loss is not consciously perceived.
- Burn victims experience significantly higher insensible water loss.
- Sweat: Water loss through sweat varies widely, influenced by heat and exercise. High levels of sweat can cause significant loss (1-2 L/hour).
- Feces: Small amounts of water are lost in feces (100 ml/day). Diarrhea massively increases water loss.
- Kidneys: The kidneys excrete water (urine) to adjust fluid balance.
Body Fluid Compartments
- Body fluid is divided mainly into extracellular fluid (ECF) and intracellular fluid (ICF).
- ECF comprises interstitial fluid and blood plasma.
- Transcellular fluid is a small compartment in ECF, containing materials in synovial, peritoneal, pericardial, intraocular spaces, and cerebrospinal fluid.
- Normal total body water for a 70 kg adult is roughly 42 liters.
- The fluid percentage in a person is varied by age, sex, and obesity.
Blood Volume
- Blood volume is about 7% of body weight (approximately 5 liters in adults).
- Plasma is the noncellular component (60% of blood), and red blood cells (RBC) comprise the remainder (40%).
- Factors like sex and weight influence hematocrit.
Intracellular Fluid Compartment
- About 28 liters (40% of body weight).
- ICF composition is similar in different cells (different organisms).
Extracellular Fluid Compartment
- Approximately 14 liters (20% body weight).
- Interstitial fluid and plasma are the two major parts of ECF.
- Plasma and interstitial fluids have similar composition (excluding proteins, which are higher in plasma).
Measurement of Body Fluid Volumes
- Indicator-dilution principle is used to measure volumes.
- Mass of indicator is considered to calculate volumes accurately.
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Description
Test your knowledge on the regulation of body fluid compartments and daily water intake. This quiz covers important concepts related to fluid balance, insensible water loss, and factors affecting hydration. Perfect for students studying physiology or health sciences.