Podcast
Questions and Answers
What is the classification of Fludrocortisone?
What is the classification of Fludrocortisone?
What therapeutic actions or indications does Fludrocortisone have?
What therapeutic actions or indications does Fludrocortisone have?
Increases sodium reabsorption in renal tubules and increases potassium and hydrogen excretion, leading to water and sodium retention. Partial replacement therapy in cortical insufficiency conditions and treatment of salt-losing adrenogenital syndrome; off-label use for hypotension.
What drug interactions exist with Fludrocortisone?
What drug interactions exist with Fludrocortisone?
Decreases the effectiveness of salicylates, barbiturates, hydantoins, rifampin, and anticholinesterases.
What are the pharmacokinetics of Fludrocortisone?
What are the pharmacokinetics of Fludrocortisone?
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What are some contraindications or cautions for using Fludrocortisone?
What are some contraindications or cautions for using Fludrocortisone?
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What are the common adverse effects of Fludrocortisone?
What are the common adverse effects of Fludrocortisone?
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What nursing considerations are important when administering Fludrocortisone?
What nursing considerations are important when administering Fludrocortisone?
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Study Notes
Fludrocortisone Overview
- Classification: Fludrocortisone is a mineralocorticoid.
Therapeutic Actions/Indications
- Promotes sodium reabsorption in renal tubules, enhances potassium and hydrogen excretion.
- Results in water and sodium retention.
- Used as partial replacement therapy in conditions of cortical insufficiency.
- Treats salt-losing adrenogenital syndrome.
- Off-label use includes treatment for hypotension.
Drug Interactions
- Fludrocortisone may decrease the effectiveness of:
- Salicylates
- Barbiturates
- Hydantoins
- Rifampin
- Anticholinesterase agents
Pharmacokinetics
- Administered orally (PO).
- Metabolized by the liver and excreted in urine.
- Exhibits a gradual onset of action.
Contraindications/Cautions
- Not suitable for patients with:
- Allergy to the drug
- Severe hypertension
- Heart failure or cardiac disease
- Pregnancy and lactation
- Infection
- High sodium intake can lead to severe hypernatremia.
Adverse Effects
- Potential side effects include:
- Frontal and occipital headaches
- Arthralgia (joint pain)
- General weakness
- Increased blood volume leading to edema
- Hypertension and heart failure
- Skin rash and risk of anaphylaxis
- Hypokalemia (low potassium levels)
Nursing Considerations
- Administer only with appropriate glucocorticoids to control electrolyte balance.
- Increase dosage during stress to prevent adrenal insufficiency.
- Regularly monitor for hypokalemia.
- Discontinue the medication if signs of overdose appear.
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Description
This set of flashcards covers key concepts related to Fludrocortisone, including its classification as a mineralocorticoid and its therapeutic actions. Ideal for students in pharmacology or medical courses, these cards will help reinforce understanding of its role in sodium reabsorption and treating various conditions. Review essential information efficiently and effectively.
