First-Order Elimination Pharmacokinetics
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Questions and Answers

What does first-order elimination pharmacokinetics refer to?

  • A process in which the amount or concentration of drug in the body diminishes linearly over time
  • A process in which the amount or concentration of drug in the body diminishes logarithmically over time (correct)
  • A process in which the amount or concentration of drug in the body remains constant over time
  • A process in which the amount or concentration of drug in the body increases over time

    • What is the half-life (t1/2) of a drug?

  • The time required for the drug to reach its peak concentration
  • The time required for the drug to be absorbed into the body
  • The time required to eliminate one-half of the drug (correct)
  • The time required to eliminate all of the drug

    • How does the rate of elimination (RE) vary with drug concentration?

  • The rate of elimination is proportional to the drug concentration (correct)
  • The rate of elimination is not related to drug concentration
  • The rate of elimination is inversely proportional to the drug concentration
  • The rate of elimination is constant regardless of drug concentration

    • What does the elimination rate constant, K, express?

    <p>The fraction or percentage of the total amount of drug present in the body that is removed at any instant in time</p> Signup and view all the answers

    How does the amount or concentration of drug lost in each 1-hour interval diminish over time?

    <p>Diminishes logarithmically over time</p> Signup and view all the answers

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