Firefly Tail and Opioids Quiz
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Questions and Answers

What endogenous ligand would make the firefly’s tail glow yellow?

  • GABA
  • Serotonin
  • Endorphins (correct)
  • Anandamide

What is the threshold dose of morphine for this firefly?

  • 15 mg
  • 50 mg
  • 5 mg
  • 25 mg (correct)

If fentanyl is 100 times more potent than morphine, what dose of fentanyl is needed to make the firefly’s tail glow yellow at 50% brightness?

  • 0.15 mg (correct)
  • 5 mg
  • 1500 mg
  • 15 mg

After building tolerance to opioids by taking morphine twice a day for a month, what brightness will the firefly's tail glow at with a 15 mg dose of morphine?

<p>Under 50% (A)</p> Signup and view all the answers

When the firefly takes a 15 mg dose of naloxone, at what brightness does its tail glow?

<p>0% (D)</p> Signup and view all the answers

After taking acetaminophen for a month, what percentage brightness will the firefly's tail glow at when given 25 mg of morphine?

<p>Less than 50% (B)</p> Signup and view all the answers

What will happen if a mu-opioid receptor partial agonist is given to the special firefly species?

<p>It will glow yellow (C)</p> Signup and view all the answers

What is the mechanism of action of an opioid overdose reversal agent?

<p>Blocking opioid receptors (B)</p> Signup and view all the answers

What aspect of morphine's characteristics is indicated by its therapeutic index?

<p>Its safety margin (D)</p> Signup and view all the answers

Which type of drug would directly activate the mu-opioid receptor?

<p>Mu-opioid receptor partial agonist (A)</p> Signup and view all the answers

How would a special firefly species react if given morphine, based on the text?

<p>It will not glow at all (D)</p> Signup and view all the answers

Why are mu-opioid receptor antagonists considered important in opioid overdose situations?

<p>To block the effects of opioids and reverse an overdose (A)</p> Signup and view all the answers

What is the therapeutic index (Lethal Dose/ Effective Dose) for morphine?

<p>100 (A)</p> Signup and view all the answers

Which of the following is an example of a mu-opioid receptor partial agonist?

<p>Buprenorphine (A)</p> Signup and view all the answers

What happens to the special firefly's glow when given a dose of morphine under 5mg?

<p>It does not glow at all (D)</p> Signup and view all the answers

What physical and psychological symptoms occur when use of an addictive substance is discontinued?

<p>Withdrawal (A)</p> Signup and view all the answers

Which agent can be used to reverse an opioid overdose?

<p>Naloxone (C)</p> Signup and view all the answers

Which type of receptor is the mu-opioid receptor?

<p>G-coupled protein receptor (B)</p> Signup and view all the answers

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