Fioricet Drugs Flashcards

Fioricet Overview

• Fioricet is the brand name for butalbital, acetaminophen, and caffeine.
• Classified as an analgesic, primarily used for headache relief.

Indications

• Labeled for relief of tension or muscle contraction headaches.

Dosage Form

• Available in tablet form for administration.

Mechanism of Action (MOA)

• Acetaminophen: Analgesic effect achieved by inhibiting prostaglandin synthesis in the central nervous system (CNS) and blocking pain impulse generation peripherally.
• Butalbital: Depresses sensory cortex by inhibiting conduction in the reticular formation at the thalamus level.
• Caffeine: Acts as a CNS stimulant by inhibiting phosphodiesterase, increasing cAMP accumulation.

Adverse Effects

• Common side effects include dizziness, drowsiness, and lightheadedness.

Pregnancy Category

• Classified as Category C, indicating risk cannot be ruled out during pregnancy.

Counseling Points

• Caution advised due to potential drowsiness; avoid operating heavy machinery or activities requiring mental alertness.
• Alcohol intake should be avoided while on this medication.
• Can be taken with food or milk to minimize gastrointestinal upset.
• Patients should not exceed the prescribed dosage.
• Warning regarding potential habit-forming nature of the medication.
• Seek medical advice if severe or persistent side effects occur.
• If a dose is missed, skip it and resume normal dosing schedule.

Storage Instructions

• Store in a cool, dry environment, away from sunlight and out of reach of children.