24 Questions
Which component significantly enhances the effectiveness of Antifoam A in collapsing bubbles?
Hydrophobic silica gel particles
What is the most well-known type of pharmaceutical grade antifoam used for extracorporeal devices?
Antifoam A
What is the mechanism by which Antifoam A collapses bubbles?
Direct 'pin like' mechanical shock
Which type of filter is typically made of a woven polyester mesh and is pleated to allow for a larger surface area in a confined space?
Screen filter
What is the size range of filters used in cardiac surgery?
0.2 μm to 40 μm
Which antifoaming agent is the most widely used in extracorporeal devices?
Polydimethylsiloxane (PDMS)
Which type of filter is designed to remove debris and gross air?
High-efficiency polyester depth filter
What is the pore size range of arterial line filters?
20 μm to 40 μm
Which antifoaming agent is less expensive and widely used in extracorporeal devices?
Antifoam A
Which two components are present in Foam A, a pharmaceutical grade antifoam used for extracorporeal devices?
Polydimethylsiloxane and hydrophobic silica gel
What is the mechanism by which Antifoam A enhances the effectiveness of collapsing bubbles?
Dewetting of hydrophobic silica particles by the bubble film
Which statement about Antifoam A is true?
It is one of the most hydrophobic dewetting surfaces available
Which type of filter is designed to create a tortuous path between fibers and retain particles mechanically?
Depth filter
What is the pore size range of gas line filters?
0.2 μm to 40 μm
What is the most well-known type of pharmaceutical grade antifoam used for extracorporeal devices?
Antifoam A
Which two components are present in Foam A, a pharmaceutical grade antifoam used for extracorporeal devices?
Polydimethylsiloxane and silicone dioxide
What is the mechanism by which Antifoam A collapses bubbles?
Dewetting of hydrophobic silica particles by the bubble film
What is the most well-known type of pharmaceutical grade antifoam used for extracorporeal devices?
Antifoam A
Which type of surface is hydrophobic silica gel particles treated with in Antifoam A?
PDMS coating
What is the mechanism by which Antifoam A collapses bubbles?
Mechanical shock
Which component may be present in Antifoam A and can include heavy metals?
Heavy metals
Which type of filter is typically made of a woven polyester mesh and is pleated to allow for a larger surface area in a confined space?
Screen filter
What is the pore size range of gas line filters?
0.2 microns
Which antifoaming agent is the most widely used in extracorporeal devices?
Polydimethylsiloxane (PDMS)
Study Notes
Antifoam A
- Silicon oil is the component that significantly enhances the effectiveness of Antifoam A in collapsing bubbles.
- Antifoam A is the most well-known type of pharmaceutical grade antifoam used for extracorporeal devices.
Mechanism of Antifoam A
- Antifoam A collapses bubbles through a mechanism where silicon oil spreads on the surface of the bubble, reducing its surface tension, and hydrophobic silica gel particles break the bubble by absorbing the surfactant.
Filters
- Mesh filters are typically made of a woven polyester mesh and are pleated to allow for a larger surface area in a confined space.
- Screen filters are designed to remove debris and gross air.
- Depth filters are designed to create a tortuous path between fibers and retain particles mechanically.
Filter Pore Sizes
- Arterial line filters have a pore size range of 20-40 μm.
- Gas line filters have a pore size range of 10-30 μm.
Antifoaming Agents
- Antifoam A is the most widely used antifoaming agent in extracorporeal devices.
- Antifoam B is less expensive and widely used in extracorporeal devices.
Composition of Foam A
- Foam A, a pharmaceutical grade antifoam, contains silicon oil and hydrophobic silica gel particles.
Surface Treatment of Hydrophobic Silica Gel Particles
- Hydrophobic silica gel particles in Antifoam A are treated with a hydrophobic surface.
Potential Component in Antifoam A
- Heavy metals may be present in Antifoam A.
Test your knowledge about different types of filters used for air and water purification. Learn about depth filters and their ability to mechanically retain particles, as well as the use of defoamers in some models. Explore the concept of screen filters and their common application.
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